Geochemistry of phosphate and glauconites of ODP Leg 128 samples

Glauconites and phosphates have been detected in almost all investigated samples at Sites 798 (uppermost Miocene or lower Pliocene to Pleistocene) and 799 (early middle Miocene to Pleistocene). Autochthonous occurrences appear in very minor quantities (generally below 0.2%) throughout the drilled sequences, whereas allochthonous accumulations are limited to the lower Pliocene or uppermost Miocene sequence at Site 798 (glauconites) and to the upper and middle Miocene sequence at Site 799 (upper and middle Miocene: glauconites; middle Miocene: phosphates). X-ray fluorescence, microprobe, and bulk chemical analyses indicate high variabilities in cations and anions and generally low oxide totals. This is probably related to the substitution of phosphate and fluoride aniors by hydroxide and carbonate anions in phosphates and to the depletion of iron, aluminum, and potassium cations and the enrichment in hydroxide and crystal water in glauconites. Gradients in pore-water contents of dissolved phosphate and fluoride at Sites 798 and 799 suggest a depth of phosphate precipitation between 30 and 50 mbsf, with fluoride as the limiting element for phosphate precipitation at Site 798. Phosphate and fluoride appear to be balanced at Site 799. Crude extrapolations indicate that the Japan-Sea sediments may have taken up approximately 7.2*10**10 g P total/yr during the Neogene and Pleistocene. This amount corresponds to approximately 0.3% of the estimated present-day global transfer of phosphorus into the sediments and suggests that the Japan Sea constitutes an average sink for this element. The two main carriers of phosphorus into the present Japan Sea are the Tshushima and the Liman currents, importing approximately 6.6*10**10 g P and 5.7*10**10 g P per year, respectively. Bulk chemical analyses suggest that at least 36% of P total in the sediments is organically bound phosphorus. This rather high value, which corresponds to the measured Japan-Sea deep-water P organic/P total ratios, probably reflects rapid transport of organic phosphorus into the depth of the Japan Sea.

Carbohydrate-deficient glycoprotein syndrome type V: Deficiency of dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase

Deficiency of dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase is the cause of an additional type of carbohydrate-deficient glycoprotein syndrome (CDGS type V). Clinically this type resembles the classical type Ia of CDGS caused by the deficiency of phosphomannomutase. As a result of the glucosyltransferase deficiency in CDGS type V nonglucosylated lipid-linked oligosaccharides accumulate. The defect is leaky and glucosylated oligosaccharides are found on nascent glycoproteins. The limited availability of glucosylated lipid-linked oligosaccharides explains the incomplete usage of N-glycosylation sites in glycoproteins. This finding is reflected in the presence of transferrin forms in serum that lack one or both of the two N-linked oligosaccharides and the reduction of mannose incorporation to about one-third of control in glycoproteins of fibroblasts.

In Vitro Studies with Purified Components Reveal Signal Recognition Particle (SRP) and SecA/SecB as Constituents of Two Independent Protein-targeting Pathways of Escherichia coli

The molecular requirements for the translocation of secretory proteins across, and the integration of membrane proteins into, the plasma membrane of Escherichia coli were compared. This was achieved in a novel cell-free system from E. coli which, by extensive subfractionation, was simultaneously rendered deficient in SecA/SecB and the signal recognition particle (SRP) components, Ffh (P48), 4.5S RNA, and FtsY. The integration of two membrane proteins into inside-out plasma membrane vesicles of E. coli required all three SRP components and could not be driven by SecA, SecB, and ΔμH+. In contrast, these were the only components required for the translocation of secretory proteins into membrane vesicles, a process in which the SRP components were completely inactive. Our results, while confirming previous in vivo studies, provide the first in vitro evidence for the dependence of the integration of polytopic inner membrane proteins on SRP in E. coli. Furthermore, they suggest that SRP and SecA/SecB have different substrate specificities resulting in two separate targeting mechanisms for membrane and secretory proteins in E. coli. Both targeting pathways intersect at the translocation pore because they are equally affected by a blocked translocation channel.

Teoria Geral dos Sistemas e Turismo: reflexão e trajetória

Também conhecida por inúmeras outras denominações, como sistemismo e abordagem sistêmica, a Teoria Geral dos Sistemas, proposta pelo austríaco e biólogo, Ludwig Von Bertalanffy, teve sua construção entre os anos 20 e 30, embora tenha apenas sido publicada e veiculada somente anos mais tarde. Importante ressaltar que seu maior propósito foi o de colocar fim no cartesianismo que permeava a ciência da época, na tentativa de demonstrar que algumas realidades careciam de análises mais holísticas e subjetivas. Assim, o presente trabalho possui como seu maior objetivo, o interesse em apresentar o postulado de referida teoria e, da mesma maneira, refletir acerca de suas proposições, demonstrando como fora aceita pelas inúmeras áreas do conhecimento e, por conseqüência, pelos estudos do Turismo. Especificamente, toda a discussão do artigo busca apresentá-la como método pertinente para a análise da atividade turística, dada sua complexidade. Para tanto, para a consecução do estudo, utilizou-se basicamente de análise bibliográfica relacionada à temática, tanto em sua forma geral como específica às discussões do turismo, já que não foi interesse do mesmo se aprofundar no que concerne à sua aplicabilidade. Como resultados gerados a partir das reflexões, tem-se que mesmo não sendo utilizada como método fim de análise, não se pode omitir o fato de que a Teoria Geral dos Sistemas pode servir de base para outras técnicas de análise, da mesma maneira que os estudos, embora avancem, parecem não acompanhar o próprio dinamismo da atividade.

Solennizzandosi la centenaria commemorazione dell' incoronazione di M. V. sul monte presso Varese : iscrizioni e poesie.

Acquisition made accessible thanks to a 2015-2017 grant from the Council on Libraries and Information Resources.

1. Wanderausstellung des Verbandes der Kunstfreunde in den Ländern am Rhein.

At head of title: Unter allerh. Protektorate Sr. Kgl. Hoh. des Grossherzogs Ernst Ludwig von Hessen u. bei Rhein.

Sinfonie in C dur.

Cover title.

Toldi szerelme : zenedráma három felvonásban = Toldi's Liebe : Musikdrama in drei Aufzügen /

German translation by Ludwig von Dóczi.

Myriapodes, Collemboles,

Cover-title.

Sisto V : il creatore della nuova roma /

Mode of access: Internet.

The life of Beethoven, including his correspondence with his friends, numerous characteristic traits, and remarks on his musical works.

"Systematic catalogue of all the original works by Ludwig von Beethoven, as published by T. Haslinger, from Vienna": v. 2, p. 377-384.