Relação entre materiais dentários e o complexo dentino-pulpar

Despite the strong valorization of the esthetics and its relationship with restorative materials, the biological principles of any clinical procedure are extremely important to maintain the vitality of the dentin-pulp complex. Dentin and pulp tissue are susceptible to different kinds of irritants such as toxins from microorganisms, traumatic procedures of cavity preparation, as well as toxic components released by restorative materials applied in non recommended clinical situations. Initially, the pulp responds to irritation by starting an inflammatory reaction which involves outward movement of dentinal fluid and intratubular deposition of immunoglobulins, upregulation of odontoblast activities, presence of immune cells and their cytokines as well as local expression of neuropeptides and chemokines. After these initial events, the inflammation process can be resolved associated or not to sclerotic dentin formation and reactionary dentin deposition. If high intensity offensive stimuli are applied to the dentin-pulp complex, death of odontoblasts takes place and consequently pulp ageing or even partial necrosis of this tissue may occurs. Thereby, clinicians need to be aware about the physiological and pathological features of the dentin-pulp complex as well as the possible biological consequences of different clinical procedures. In this way, the dentists should be able to carry out minimally aggressive operative techniques and to select the more appropriate restorative materials for each specific clinical situation in order to obtain excellent clinical results associated to the maintenance of pulp vitality.

Erosive potencial of energy drinks on the dentine surface

Coordenação de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

A narrativa visual de Lourenço Mutarelli: o uso fragmentado da linguagem dos quadrinhos em seus primeiros romances gráficos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Trueperella pyogenes multispecies infections in domestic animals: a retrospective study of 144 cases (2002 to 2012)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Acoustic radiation force impulse (ARFI) elastography of the spleen in healthy adult cats - a preliminary study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Immunoexpression of ROCK-1 and MMP-9 as prognostic markers in breast cancer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Deficiência auditiva: estudos clínicos sobre o narcisismo materno

The diagnosis of hearing loss (HL) in a child constitutes a crisis, includinga possible crash in parental narcissism, requiring an individual, matrimonial andfamiliar reorganization process. The mother is the main figure to devote herselfattending the baby and generally takes the most responsibilities in the processof habilitation or rehabilitation of the child, while still having to deal with her frustratedexpectations and narcissism. This study aims to investigate the effects of a deaf child’s birth on the mother’s narcissism. Here understood as a normal stage of psychosexual development of the human being, needed for life preservation, nota pathology. Five different clinical pratical studies were developed with mothers of deaf children that were diagnosed less than one year ago. The data were collected using individual semi-structured interviews and Thematic Apperception Test (TAT). Based on these studies it was found that the birth of a deaf child makes it difficult to obtain the expected narcissist satisfaction. The mother, investing all her affection and longing almost only on her child, hopes to rebuild her dream obtaining the "cure" and "normality" of her baby by submitting him/her to a cochlear implant.

Estudo clínico retrospectivo de restaurações cerâmicas do tipo laminado sobre dentes com ou sem preparo dentário: 1 a 5 anos de acompanhamento

Pós-graduação em Odontologia - FOA

Papel dos receptores TLR2 e TLR4 na produção de citocinas em pacientes chagásicos crônicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A aplicação da abordagem do Tecnógeno na identificação e classificação dos terrenos e depósitos tecnogênicos no ambiente urbano de Guarapuava-PR

Pós-graduação em Geografia - FCT

Aromaterapia e Ansiedade: revisão integrativa da literatura

This study aimed at investigating, in the national and international scientific literature, how aromatherapy is used as a therapeutic tool to reduce anxiety. It is a bibliographic study that adopted integrative literature review as a method. Studies published on databases Scielo, Medline and Cinahl from 2008 to 2012 were selected. A sample of 20 scientific articles was analyzed, and of these, 13 had an experimental and a quasi--experimental design whereas 07 were systematic or integrative reviews. The synthesis of knowledge sho-wed that aromatherapy represents a safe therapeutic practice although it is still underestimated in health care practices. The construction of evidence levels was not possible due to discrepancies in the studied populations, in research designs, the various essential oils used and the different methods for aromatherapy application. The knowledge gaps identified in these studies are related to the need to develop new forms to evaluate the effectiveness of this practice, including the therapist-patient relationship and the different communication forms that are intrinsic to aromatherapy.

Genomic gains in prostatic carcinoma and proliferative inflammatory atrophy in dogs

The dog can spontaneously develop prostate cancer and consequently can be used as an experimental model for prostatic diseases associated with aging, including benign prostate hyperplasia (BPH) and prostate carcinoma (PCa). DNA copy number variations (CNVs) have been used to identify genes associated with cancer development and progression. DNA microarray based comparative genomic hybridization (aCGH) is a technique that allows to identify copy number of thousands of genes throughout the genome. aCGH was used to identify genomic regions with significantly different DNA copy number in three benign prostatic hyperplasia (BPH), four proliferative inflammatory atrophy (PIA), and 14 canine prostate carcinoma (PCa). Five histologically normal prostate tissue were used as reference. Genomic DNA was extracted from formalin fixed and paraffin embedded samples and CNVs data was evaluated in Canine Genome CGH Microarray 4x44K (G2519F, Design ID021193, Agilent). Data analysis was performed using Genomic Workbench Standard Edition 5.0.14 (Agilent). PCa showed higher number of altered genes related to canonical diseases process, cellular functions and molecular pathways as well as greater inter-relationship between genes, compared with PIA and BPH. In conclusion, PCa showed a more complex genotype, being losses the most frequent genomic changes. Some discrepancies between genomic alterations in human and canine carcinomas may indicate the different clinical behavior of these tumors in these two species. In addition, it was observed was an ascending pattern of genomic complexity in BPH, PIA and CA consistent with a model of multistep tumor progression.

Índice de resistência múltipla aos antimicrobianos, concentração inibitória e beta-lactamases de espectro estendido em linhagens de Proteus mirabilis e Proteus vulgaris isoladas de diferentes afecções em animais domésticos

Pós-graduação em Medicina Veterinária - FMVZ

Dos sujeitos e lugares da punição: da passagem do/a jovem perigoso/a para o/a jovem em perigo: um estudo das dimensões do dispositivo da gestão dos riscos e de controle social da juventude

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Genes associados à virulência e multirresistência de antimicrobianos em linhagens Trueperella Pyogenes isoladas de mastite e outras afecções em animais domésticos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)