996 resultados para AK4-227


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2003 年1 月, 在广西壮族自治区天峨县红水河水系地下河采集到一批盲鱼标本。经鉴定, 为高原鳅 属Triplophysa 一未经发表的新种。新种天峨高原鳅Triplophysa tianeensis sp1nov1 与个旧盲高原鳅T. gejiuensis 、 石林盲高原鳅T. shilinensis 、阿庐高原鳅T. aluensis 和南丹高原鳅T. nandanensis 相似; 本新种腹鳍末端不达 肛门, 尾鳍分枝鳍条16 , 可进一步与个旧盲高原鳅和石林盲高原鳅(腹鳍末端达到肛门, 尾鳍分枝鳍条14~ 15) 相区别; 本新种背鳍起点位于体之中点、腹鳍起点之后, 肛门紧靠臀鳍起点, 可进一步与阿庐高原鳅(背 鳍起点靠近吻端、位于腹鳍起点之前, 肛门距臀鳍起点仍有一段距离) 相区别。本新种与同分布于红水河水系 的南丹高原鳅Triplophysa nandanensis Lan et al1 较为相似; 但二者区别明显: 新种背鳍分枝鳍条7 、胸鳍分枝鳍 条9 、腹鳍分枝鳍条6 、背鳍外缘平截、背鳍起点位于腹鳍起点之后, 后者背鳍分枝鳍条8 、胸鳍分枝鳍条10~ 11 、腹鳍分枝鳍条7 、背鳍外缘凹入、背鳍起点位于腹鳍起点之前; 此外, 新种的穴居特征更为显著: 眼极度 退化、头长为眼径1618~3218 (2510) 倍、部分个体无色素斑且各鳍无斑点, 而南丹高原鳅眼小、头长为眼径 417~910 (715) 倍、体和头背侧密布云状斑且各鳍均具点状斑。

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A new species, Triplophysa longipectoralis, is described from Liujiang River, Guangxi, China. The new species is distinguished from other species of Triplophysa by the following combination of characters: pectoral fin highly developed, reaching beyond pel

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研究以昆明山海棠根部水抽提物(Tripterygium hypoglaucum (Level) Hutch,THH)处理中国仓鼠V_(79)细胞,通过检测V_(79)细胞C-M细胞频率以及二酰基甘油(1,2-diacylgcerol,DAG)的含量测定,分析了THH诱发非整倍体与细胞醇磷酯信号通路的关系。结果指出:THH能在1mg/ml、2mg/ml两个剂量上使V_(79)细胞的DAG含量显著升高(P<0.001),并明显的提高C-M细胞频率(P<0.05),提示肌醇酯信号通路是介导THH诱发非整倍体的途径之一。

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In this review we describe current scientific and technological issues in the quest to reduce aeroengine noise, in the face of predicted rapid increases in the volume of air traffic, on the one hand, and increasingly strict environmental regulation, on the other. Alongside conventional ducted turbofan designs, new open-rotor contra-rotating power plants are currently under development, which present their own noise challenges. The key sources of tonal and broadband noise, and the way in which noise propagates away from the source, are surveyed in both cases. We also consider in detail two key aspects underpinning the flow physics that continue to receive considerable attention, namely the acoustics of swirling flow and unsteady flow-blade interactions. Finally, we describe possible innovations in open-rotor engine design for low noise.

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Sodium rutin sulfate (SRS) is a sulfated rutin modified from the natural flavonol glycoside rutin. Here, we investigated its in vitro anti-HIV and -HSV activities and its cytotoxic profile. Fifty percent inhibitory concentration (IC50) values of SRS against HIV-1 X4 virus IIIB, HIV-1 R5 isolates Ada-M and Ba-L were 2.3 +/- 0.2, 4.5 +/- 2.0 and 8.5 +/- 3.8 mu M with a selectivity index (SI) of 563, 575 and 329, respectively. Its IC50 against primary R5 HIV-1 isolate from Yunnan province in China was 13.1 +/- 5.5 mu M, with a Sl of 197. In contrast, unsulfated rutin had no activity against any of the HIV-1 isolates tested. Further study indicated that SRS blocked viral entry and virus-cell fusion likely through interacting with the HIV- I envelope glycoprotein. SRS also demonstrated some activity against human herpes simplex virus (HSV) with an IC50 of 88.3 +/- 0.1 mu M and a Sl of 30. The 50% cytotoxicity concentration (CC50) of SRS was >3.0 mM, as determined in human genital ME 180, HeLa and primary human foreskin fibroblast cells. Minimum inhibitory concentration of SRS for vaginal lactobacilli was >3.0 mM. These results collectively indicate that SRS represents a novel candidate for anti-HIV-1/HSV microbicide development. (C) 2007 Elsevier B.V. All rights reserved.