979 resultados para 312-U1256D


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O objetivo do trabalho foi quantificar o teor de nitrato e nitrito de sódio em amostras de lingüiças frescal de frango e pernil, em quatro lotes distintos de sete produtores. O delineamento experimental foi inteiramente ao acaso, com tratamentos dispostos no esquema fatorial 7x4. Aos dados obtidos aplicou-se análise de variância, para obter o quadrado médio do resíduo. Para verificar a homogeneidade dos experimentos utilizou-se o teste de Hartley. Prosseguiu-se à análise conjunta para comparar os dois tipos de lingüiça. Aplicou-se o esquema fatorial 7x4x2 e obteve se o F significativo. Aplicou-se o teste de Tukey ao nível de 1% de significância. Os resultados indicam que as amostras de lingüiça frescal de frango apresentaram valores entre 7,6 e 312,5 ppm para a fração de nitrato de sódio e valores entre 1,2 e 221 ppm para a fração de nitrito; para as amostras de lingüiça frescal de pernil, os teores obtidos estiveram entre 8,6 e 363,6 ppm para a fração de nitrato e entre 0,6 a 162,2 ppm para a de nitrito. Entre os lotes de lingüiça de frango, a variação esteve entre 7,6 e 312,5 ppm para a fração de nitrato e entre 1,2 e 221ppm para a de nitrito; as amostras de lingüiça frescal de pernil apresentaram valores de 100 a 104,3 ppm para nitrato e de 0,6 a 162,2 ppm para nitrito. 7,1% das amostras estavam em desacordo com a legislação.

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Reetta Muhosen väitöskirja Opinteitä ikääntyvien yliopistoon : sotien sukupolvi ja yliopiston ylistys (Jyväskylän yliopisto 2014).

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The objective of this study was to monitor carrot seed hydration in water and osmotic solutions to define appropriate conditions for priming treatment. Two Brasília cultivar carrot seed lots were used. Seeds were imbibed in -1.0 and -1.2 MPa PEG 6000 osmotic solutions and in distilled water, in an incubator BOD at 20ºC, using two different hydration methods: imbibition in moistened paper towel sheets and in aerated solutions. The imbibition curves for each seed lot were drawn after determining seed moisture content at 2, 4, 6, 8, 10, 12, 24, 48, 72, 96 hours hydration in water and after 2, 4, 6, 8, 10, 12, 24, 48, 72, 96, 120, 144, 168, 192, 216, 264, 312 hours hydration in PEG 6000 solutions. Seed hydration in distilled water was faster than in PEG 6000 solutions; the primary root protrusion occurred at 48 hours imbibition as seeds reached 54% moisture content. Osmotic conditioning of carrot seeds should be performed by imbibition in PEG 6000 -1.0 or -1.2 MPa solutions to attain 40% and 45% moisture content (moistened paper) or 40% and 45% (aerated solutions).

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Yleissuunnittelun tavoitteena on ollut kohdentaa ympäristönsuojelutoimenpiteet tarkoituksenmukaisille alueille ja kannustaa viljelijöitä ympäristötekoihin. Alkuvuosina Uudellamaalla keskityttiin suojavyöhykkeisiin, mutta sen jälkeen yleissuunnitelmissa on etsitty sopivia kohteita myös luonnon monimuotoisuuden edistämiseen ja kosteikkojen perustamiseen. Suojavyöhykkeiden yleissuunnitelmat kattavat lähes koko Uudenmaan. Suunnitelmien teon yhteydessä ja eri hankkeissa suojavyöhyk-keitä on markkinoitu viljelijöille. Suojavyöhykkeiden suosio oli ensimmäisellä ympäristötukikaudella 1995–1999 vähäistä, mutta on kas-vanut vuosien kuluessa osittain viljelijöille suunnatun täsmämarkkinoinnin ansiosta. Vuonna 2015 alkaneella ympäristökorvauskaudella suojavyöhykkeiden hakumenettelyä kevennettiin ja tukitasoa nostettiin. Suojavyöhykkeiden määrä yli kolminkertaistui noin 4 300 heh-taariin. Kosteikkojen perustamisessa ongelmana on ollut ympäristötuen vaatimusten täyttäminen ja ympäristökorvauksen piirissä olevia kos-teikoita on Uudellamaalla vain muutama. Luonnon monimuotoisuuden edistämisen tuen hakijoiden määrä on vähentynyt, mutta haetut kohteet ovat varsin suuria, jolloin sopimusala on kasvanut viime vuosina. Nykyisenkaltaisia yleissuunnitelmia ei ainakaan lähivuosina enää toteuteta. Jatkossa tulisi hyödyntää tehtyjä yleissuunnitelmia ja koh-dentaa suojavyöhykkeitä peltolohkoille, joissa niistä on kaikkein suurin hyöty.

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Prostate cancer (PCa) has emerged as the most commonly diagnosed lethal cancer in European men. PCa is a heterogeneous cancer that in the majority of the cases is slow growing: consequently, these patients would not need any medical treatment. Currently, the measurement of prostate-specific antigen (PSA) from blood by immunoassay followed by digital rectal examination and a pathological examination of prostate tissue biopsies are the most widely used methods in the diagnosis of PCa. These methods suffer from a lack of sensitivity and specificity that may cause either missed cancers or overtreatment as a consequence of over-diagnosis. Therefore, more reliable biomarkers are needed for a better discrimination between indolent and potentially aggressive cancers. The aim of this thesis was the identification and validation of novel biomarkers for PCa. The mRNA expression level of 14 genes including AMACR, AR, PCA3, SPINK1, TMPRSS2-ERG, KLK3, ACSM1, CACNA1D, DLX1, LMNB1, PLA2G7, RHOU, SPON2, and TDRD1 was measured by a truly quantitative reverse transcription PCR in different prostate tissue samples from men with and without PCa. For the last eight genes the function of the genes in PCa progression was studied by a specific siRNA knockdown in PC-3 and VCaP cells. The results from radical prostatectomy and cystoprostatectomy samples showed statistically significant overexpression for all the target genes, except for KLK3 in men with PCa compared with men without PCa. Statistically significant difference was also observed in low versus high Gleason grade tumors (for PLA2G7), PSA relapse versus no relapse (for SPON2), and low versus high TNM stages (for CACNA1D and DLX1). Functional studies and siRNA silencing results revealed a cytotoxicity effect for the knock-down of DLX1, PLA2G7, and RHOU, and altered tumor cell invasion for PLA2G7, RHOU, ACSM1, and CACNA1D knock-down in 3D conditions. In addition, effects on tumor cell motility were observed after silencing PLA2G7 and RHOU in 2D monolayer cultures. Altogether, these findings indicate the possibility of utilizing these new markers as diagnostic and prognostic markers, and they may also represent therapeutic targets for PCa.

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Kirjallisuusarvostelu

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Satu-Mari Janssonin väitöskirja Teatteri ja draama työn oppimismuotoina (Helsingin yliopisto 2015).

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1890/05/30 (Numéro 312).

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1896/11/08 (Numéro 312).

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1885/01/17 (Numéro 312).