863 resultados para price drop ratio
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
We find that the vast majority of students taking an advanced undergraduate finance course show a preference for luck in a classroom experiment. In Phase I of the experiment part of the students, group A, were asked to guess a coin toss five times in a row. In Phase II the rest of the students, group B, were given 10 EUR to bet on some of the Group A students taking a second go at guessing a sequence of five coin tosses (Phase III). Group B students’ bets were by default allocated to the worse performing student in Phase I. Switching to better performing Group A students was costly. A total of 23 out of 28 students were willing to pay for switching and thus showed a preference for luck.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
PURPOSE: To evaluate the prognostic and predictive value of Ki-67 labeling index (LI) in a trial comparing letrozole (Let) with tamoxifen (Tam) as adjuvant therapy in postmenopausal women with early breast cancer. PATIENTS AND METHODS: Breast International Group (BIG) trial 1-98 randomly assigned 8,010 patients to four treatment arms comparing Let and Tam with sequences of each agent. Of 4,922 patients randomly assigned to receive 5 years of monotherapy with either agent, 2,685 had primary tumor material available for central pathology assessment of Ki-67 LI by immunohistochemistry and had tumors confirmed to express estrogen receptors after central review. The prognostic and predictive value of centrally measured Ki-67 LI on disease-free survival (DFS) were assessed among these patients using proportional hazards modeling, with Ki-67 LI values dichotomized at the median value of 11%. RESULTS: Higher values of Ki-67 LI were associated with adverse prognostic factors and with worse DFS (hazard ratio [HR; high:low] = 1.8; 95% CI, 1.4 to 2.3). The magnitude of the treatment benefit for Let versus Tam was greater among patients with high tumor Ki-67 LI (HR [Let:Tam] = 0.53; 95% CI, 0.39 to 0.72) than among patients with low tumor Ki-67 LI (HR [Let:Tam] = 0.81; 95% CI, 0.57 to 1.15; interaction P = .09). CONCLUSION: Ki-67 LI is confirmed as a prognostic factor in this study. High Ki-67 LI levels may identify a patient group that particularly benefits from initial Let adjuvant therapy.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.
Resumo:
We investigated whether a single blood measurement using the minimally invasive technique of a finger prick to draw a blood sample of 5 µl (to yield a dried blood spot (DBS)) is suitable for the assessment of flurbiprofen (FLB) metabolic ratio (MR). Ten healthy volunteers who had been genotyped for CYP2C9 were recruited as subjects. They received FLB alone in session 1 and FLB with fluconazole in session 2. In session 3, the subjects were pretreated for 4 days with rifampicin and received FLB with the last dose of rifampicin on day 5. Plasma and DBS samples were obtained between 0 and 8 h after FLB administration, and urine was collected during the 8 h after administration. The pharmacokinetic profiles of the drugs were comparable in DBS and plasma. FLB's apparent clearance values decreased by 35% in plasma and DBS during session 2 and increased by 75% in plasma and by 30% in DBS during session 3. Good correlations were observed between MRs calculated from urine, plasma, and DBS samples.
Resumo:
Iowa Spirits Price Book is produced monthly details of the current prices of liquors in Iowa. Formerly titled Iowa Liquor Quarterly Spirits Price Book.