Estudo da perda da tensao do enxerto de tendão calcâneo bovino

Lesion of the anterior cruciate ligament (ACL) in the knee is a problem that affects animals as well as humans and may evolve with joint instability that is often symptomatic and incapacitating. The main option for ligament substitution is the autologous tendon graft. The graft undergoes tensioning during ACL reconstructive surgery to reestablish the normal laxity of the ACL- deficient knee. Although graft tensioning plays a fundamental role in postoperative clinical evolution, ideal tensioning levels have not been established in the literature. Therefore, graft elongation that may occur over time is still one of the main reasons for ligament reconstruction failure. In this study, ten bovine calcaneus tendons underwent two successive assays of physiological tensioning for a maximum deformation of 2.5% of the initial tendon length, maintained for 600s with force (N) values recorded at zero time (initial), 300s and 600s. At the end of the first assay, the tendon returned to its initial length and was maintained at rest for 300s and then the next tensioning assay was initiated, repeating the previous procedure. Statistical analysis revealed that tendon elongation is more pronounced during the initial 300s, reflecting a more accentuated decline in the tension values of the graft. Therefore, 300s after tensioning and fixing the graft, the surgeon can assess with more precision if the tensioning level was adequate.

Análise das dosagens e concentrações séricas da ciclosporina A em cães da raça Golden Retriever normais ou afetados pela distrofia muscular

The muscular dystrophy of Golden Retriever (GRMD) is a degenerative miopaty caused by the absence of dystrophy and it is genetically homologue of the Duchenne muscular dystrophy in humans, so, these dogs are considerably experimental models for studies on cellular therapy. Their successful depends of the adequate immunosuppression. Cyclosporin A (CsA) is indicated for that and the monitoring of the blood concentration and adverse effects are essential to viabilise the therapy. It was studied GRMD dogs, and normal dogs from the same breed, submitted for therapy with CsA, associated, on GRMD, of cell transplantation. It was evaluated blood concentration of the drug, between two or tree days using the method of FPIA. In our results we found that the CsA blood concentrations oscillated too much on six than eight of our animals. We concluded that the doses varieties individually and the correct dosage as to important as the evaluation of the blood concentration of the drug and became viable for cell therapy.

Vascularização arterial e venosa do linfonodo poplíteo em cães

Poplíteo lympho nodes in the dogs is placed, to the right and the left in popliteo an appointed space fossa, in distal part of the muscles femoral biceps, laterally and semi-tendinous, medially, projecting in the height of the face volume of the joint to femoro tibial e femoro patellar (joint of the knee). In this study twenty and five dogs, males and females adult, originating the Araçatuba municipal kennel had been used whose captures had been effected by the animal sanitary defense of this city. The arterial vessels destined to this structure always derive, of both the sides, the femoral artery distal volume and vary of 10 the 1, more frequently of 2 (7 times, 28%) to the right and of 6 the 2, equally more frequently of 2 (8 times, 32%). So soon as one has still to right 5 and 6 branches (3 times, 12%), 1, 7 and 10 (1 time, 4%). Relatively to the veins derived from this lympho nodes, always converges to the lateral safena vein, these vessels oscillates between 9 and 2, more frequently of 3 (6 times, 24%), to the right and of 12 the 2, more frequently of 3 (10 times, 40%) to the left. Thus, others deriving branches of popliteo lympho nodes right and that if they insert in the above-mentioned vein are in number of 2 and 5 (5 times, 20%), 4 and 6 (2 times, 8%) and 8 and 9 (1 time, 4%). In spite of, to the left side it is examined in number de 2 branches (6 times, 24%), 4 (4 times, 16%), 6 (3 times, 12%) and finishing 9 and 12 branches (1 time, 4%). The size of popliteo lympho node in seropositive dogs for Visceral Leishmaniasis can meets enters 7,8 × 3,8 × 6,1 a 50,0 × 20,7 × 28,5, in mm, being average 26,18 × 10,5 × 15,97 mm for right and 26,98 × 11,14 × 15,25 mm for left (concerning the measures dorsoventral, latero-lateral and cranial-caudal, respectively).

Acute phase proteins in canine lymphoma during antineoplastic chemotherapy

The lymphoma is the main hematopoietic tumor in dogs and it is characterized by the proliferation of cells from lymphoid tissue, histiocytes and its precursors. Animals with lymphoma often show changes in biochemical and hematological parameters such as non-regenerative normochromic normocytic anemia, hemolytic anemia, hypocalcaemia and monoclonal gammopathy. The development of tumor can cause alterations in serum concentrations of acute phase proteins (APPs), consequent of hepatocytes stimulus by cytokines of inflammatory action. This study aimed to quantify and qualify APPs in dogs with lymphoma, at diagnosis time and during the time of chemotherapy sessions. After syneresis, centrifugation and fractioning the serum samples of 10 healthy and 10 dogs with lymphomas, the proteins fractions were separated by polyacrilamide gel electrophoresis (SDS-PAGE) and its concentrations were determined by computer densitometry. Between 18 and 30 proteins were separated by eletrophoresis, with molecular weights ranging from 18 to 245 kDa (kilodaltons). The alpha-1-glicoprotein acid (AGP) and transferrin serum concentration showed significantly higher in dogs with lymphoma, when compared with healthy dogs at diagnosis. The alpha-1-antitripsin (AAT) serum concentrations showed significantly higher in healthy dogs, when compared with dogs with lymphoma at diagnosis. The dogs with lymphoma the albumin did not appear as negative APP. On the other hand, transferrin appeared as positive AAP at diagnosis time and during the chemotherapy sessions. Healthy dogs had AAT serum concentrations significantly higher when compared to dogs with lymphoma at diagnosis. So, in this trial, it is suggested that this protein has been shown as a negative APP in the dogs with lymphoma. These dogs presented significantly higher AGP serum concentrations, in relation to healthy dogs at diagnosis, evidencing this protein APP positive behavior in neoplasm.

Avaliação da função glomerular de cães sadios e nefropatas sob estimulação dopaminérgica

Dopamine is an endogenous compound widely used in intensive care. It has a broad spectrum of action, on the cardiovascular system and urinary tract. Increased glomerular filtration rate, renal blood flow and fractional excretion of sodium and phosphorus are expected renal effects in normal individuals, but are poorly explored in veterinary medicine. This study was conducted to evaluate the glomerular function of dogs with renal disease submitted to continuous infusion of dopamine. Different doses of dopamine were administered in healthy and nephropathic dogs. Laboratory evaluations of creatinine clearance and urinary protein/creatinine ratio were performed during and after treatments. Creatinine clearance showed dose-dependent increase in healthy dogs. In dogs with renal disease, the dose of 1μg/kg/min GFR increased slightly, without changing the urine P/C and blood pressure, while the dose of 3μg/kg/min increased urinary protein excretion.

Avaliação morfométrica, realizada pelo exame ultrassonográfico, da veia porta, veia cava caudal e aorta abdominal em cães saudáveis de diferentes pesos corpóreos

The diameters and areas of portal vein, caudal vena cava and abdominal aorta are useful measurements in dogs. These values can be easily measured by ultrasonographic exam, and variations of normality can be an important indicator of hepatic or extra-hepatic alterations. This study aimed to measure the diameter and areas of portal vein, caudal vena cava and abdominal aorta in healthy dogs, with normal corporal score, divided in groups according to the body weight, and assess whether the data are influenced by animal weight. Thirty dogs were examined and divided into three groups (Group A: ≤ 10 kg Group B: from 10.1 to 20.0 kg; Group C: ≥ 20.1 kg). To measure the diameters and areas of portal vein, caudal vena cava and abdominal aorta, the animal was kept in left lateral decubitus position and the transducer was placed on the right lateral abdominal wall, at approximately the 10 th or 11 th intercostal space, in the porta hepatis region. The diameters and areas of the portal vein, caudal vena cava and abdominal aorta were significantly lower for dogs in Group A with respect to other groups and the dogs from Groups B and C had similar results with each other. The diameters and areas of the portal vein, caudal vena cava and abdominal aorta may vary with the animal size, and reference values must be specific for small, medium and large dogs.

Noninvasive aspergillosis as a maxillary antrolith: report of a rare case.

Maxillary antrolithiasis is characterized by masses of tissue of endogenous or exogenous origin that calcify within the maxillary sinuses. Aspergillosis is a fungal disease in which the maxillary sinus is a primary site of infection. Aspergillosis mycetoma, its noninvasive form, is the most prevalent modality of the disease in the maxillary sinuses. In approximately half of the cases reported in the literature, calcification of the fungal mycelia, which later became antroliths, was verified. This article reports a rare case of the accidental discovery of a maxillary antrolith associated with noninvasive aspergillosis in an immunocompetent and asymptomatic 56-year-old woman. The diagnosis and therapeutic procedures used in treating the patient are discussed as well as the probable iatrogenic origin of the fungal pathology.

Coccidiose em cães e gatos do município de andradina, estado de são paulo, Brasil

Coccidiosis is one of the most common parasitic diseases in dogs and cats in all the world. The aim of this study was to determine the occurrence of this parasitosis in dog and cat population at the Municipality of Andradina in the State of São Paulo, from 2007 to 2009. Fecal samples from 97 cats and 93 dogs were analyzed by using the techniques of flotation in saturated sodium chloride and spontaneous sedimentation. The species were classified according to morphology of the oocysts. Cystoisospora fecal oocyst found in 71.1% (69/97) of the cats, and simple infection by C. rivolta and C. felis occurred respectively in 41.0% (16/39) and 20.5% (8/39) animals, with P ≥ 0.2319. In 39.7%(37/93) of the dogs was found positive for Cystoisospora spp. And the species C. canis identified in the largest proportion (63.9%) with P = 0.0005. From the results, we conclude that dogs and cats had high incidence of infection Cystoisospora, being C. canis and C. rivolta most observed species, respectively.

Craniometria em cães (Canis familiaris). Aspectos em crânios mesaticéfalos

In this study, a total of 25 skulls of the adult, mongrel and mesaticephalics dogs were used. Craniometric measurements for different parts of the skull were made. Cephalic indices and ratios were calculated. Certain points and landmarks on the skull are recognized in making linear measurements and are inion, bregma, nasion, prosthion, pogonion, basion, euryon, and zygion. Skull height (41,92 mm ± 3,9), skull length (177,72 mm ± 16,22), neurocranium (96,84 mm ± 7,25), viscerocranial (79,24 mm ± 8,72), basal length (140,24 mm ± 12,21), condylobasal (149,32 mm ± 12,21), snout (69,84 mm ± 7,07), nasals (50,08 mm ± 6,77), mandibular (129,88 mm ± 16,3), and of palatal (76,84 mm ± 7,01); width of neurocranium (62,24 mm ± 3,8), and zygomatic (95,44 mm ± 7,85) were obtained. Therefore, were calculated cranial index (53,83 mm ± 3,36), neurocranium (64,48 mm ± 4,69), facial (121,06 mm ± 9,18), basal (44,64 mm ± 4,17), width of the jugular processes (41 mm ± 4,2), of occipital condyles (35,48 mm ± 3,21), and of the foramen magnum (17,48 mm ± 2,27); height of the occipital triangle (38,28 mm ± 3,35), of the foramen magnum (14,36 mm ± 1,07); length of the dorsal notch (16,1 mm ± 1,12), and foramen magnum index (83,71 mm ± 14,44). Although with some differences in measurements, no significant difference was observed between the dimensions and reported to mesaticephalic skulls.

Ultrassonografia oftálmica em cães com diferentes conformações cranianas

The aim of this study was to establish mean values for intraocular structures and analyse if the differences are present for different skull conformations in dogs. In this study, 30 dogs were selected and distributed into three groups according to skull conformation; thus, group 1 (G1) was composed of brachycephalic dogs, group 2 (G2) was composed of mesocephalic dogs and group 3 (G3) was composed of dolichocephalic dogs. A and B-mode ultrasound was performed simultaneously for obtainment of measurements relating to anterior chamber depth (D1); lens thickness (D2); vitreous chamber depth (D3); and the axial length of the eye (D4). No differences were observed when comparing left and right eyes of dogs within the same skull conformation group (p>0.05). Differences were observed when comparing D3 and D4 between groups G2 and G3 (p<0.05). Skull conformation of brachycephalic dogs did not influence intraocular measurement values when compared to dolicephalic and mesocephalic dogs. Skull conformation of dolichocephalic dogs had an influence in values of vitreous chamber and the complete length of the eye when compared to mesocephalic dogs.

Efeitos da abordagem motora em idosos com demência

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de densiometria óssea de cães SRD com propriedades físicas e químicas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Potencial evocado auditivo de tronco encefálico em cães

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cinemática de cães da raça pastor alemão hígidos em displasia coxofemoral

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação ultrassonigráfica da glândula tireóide em cães hígidos de diferentes faixas etárias

Pós-graduação em Medicina Veterinária - FMVZ