990 resultados para Investigation-action


Relevância:

20.00% 20.00%

Publicador:

Resumo:

The importance of interaction between Operations Management (OM) and Human Behavior has been recently re-addressed. This paper introduced the Reasoned Action Theory suggested by Froehle and Roth (2004) to analyze Operational Capabilities exploring the suitability of this model in the context of OM. It also seeks to discuss the behavioral aspects of operational capabilities from the perspective of organizational routines. This theory was operationalized using Fishbein and Ajzen (F/A) behavioral model and a multi-case strategy was employed to analyze the Continuous Improvement (CI) capability. The results posit that the model explains partially the CI behavior in an operational context and some contingency variables might influence the general relations among the variables involved in the F/A model. Thus intention might not be the determinant variable of behavior in this context.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

An investigation into support for restrictions on people testing seropositive for HIV is reported on. Data were collected during telephone interviews with two-hundred adults aged eighteen to sixty-five in the Chicago metropolitan area. Using the analytic technique of LISREL, six models which attempt to explain support for restrictions were tested. It was found that the model best supported by the data indicates that two groups contribute to support for restrictions on HIV carriers - one due to intolerance of homosexuality and one to mistrust of public health officials regarding their control and management of the AIDS epidemic. The relevance of these findings for public health policy makers is discussed.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

In this paper, the development of bidding strategies is investigated for a wind farm owner. The optimization model is characterized by making the analysis of scenarios. The proposed approach allows evaluating alternative production strategies in order to submit bids to the electricity market with the goal of maximizing profits. The problem is formulated as a linear programming problem. An application to a case study is presented

Relevância:

20.00% 20.00%

Publicador:

Resumo:

People customarily use the extracts of plants known to have antidiarrhoeal effects without any scientific base to explain the action of the extract. For this reason, an investigation was undertaken with a view to determining the efficacy of the effects of the brute aqueous extract (BAE) of the leaves of Psidium guajava (guava), Stachytarpheta cayenensis (bastard vervain), Polygonum punctatum (water. smartweed), Eugenia uniflora (Brazil or Surinam cherry) and Aster squamatus (zé-da-silva) on the intestinal transport of water in rats and on the gastrointestinal propulsion in mice. With the exception of the BAE of S. cayenensis, all other BAE's have increased the absorption of water in one or more intestinal portion in relation to the control group. All tested BAE, except that of P. punctatum, reduced the gastrointestinal propulsion in relation to that of the control group. The results indicate that the BAE of the leaves of P. guajava, S. cayenensis, P. punctatum, E. uniflora and A. squamatus have a potential antidiarrhoeic effect to be confirmed by additional investigations in animals infected with enteropathogenic agents.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

In the context of the Bologna Declaration a change is taking place in the teaching/learning paradigm. From teaching-centered education, which emphasizes the acquisition and transmission of knowledge, we now speak of learning-centered education, which is more demanding for students. This paradigm promotes a continuum of lifelong learning, where the individual needs to be able to handle knowledge, to select what is appropriate for a particular context, to learn permanently and to understand how to learn in new and rapidly changing situations. One attempt to face these challenges has been the experience of ISCAP regarding the teaching/learning of accounting in the course Managerial Simulation. This paper describes the process of teaching, learning and assessment in an action-based learning environment. After a brief general framework that focuses on education objectives, we report the strengths and limitations of this teaching/learning tool. We conclude with some lessons from the implementation of the project.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertação apresentada à Escol a Superior de Educação de Lisboa para obtenção de grau de mestre em Ciências da Educação, especialidade Educação Especial: Problemas Graves de Cognição e Multideficiência

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This synopsis summarizes the key chemical and bacteriological characteristics of β-lactams, penicillins, cephalosporins, carbanpenems, monobactams and others. Particular notice is given to first-generation to fifth-generation cephalosporins. This review also summarizes the main resistance mechanism to antibiotics, focusing particular attention to those conferring resistance to broad-spectrum cephalosporins by means of production of emerging cephalosporinases (extended-spectrum β-lactamases and AmpC β-lactamases), target alteration (penicillin-binding proteins from methicillin-resistant Staphylococcus aureus) and membrane transporters that pump β-lactams out of the bacterial cell.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

TRANSCREA, Convertir la investigación y el conocimiento en innovación, propiedad intelectual e industrial. Terceira, 16 e 17 Fevereiro, 2011.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

O empreendedorismo social tem vindo, nas últimas décadas, a ser denominado como um novo paradigma determinante para o funcionamento da economia, em grande parte, porque a economia social tornou-se basilar na sociedade, por um lado, pelo crescimento exponencial da exclusão social, elevado desemprego e envelhecimento da população e, por outro, devido às dificuldades orçamentais dos governos. O empreendedorismo social, utilizado por Instituições Particulares de Solidariedade Social sem fins lucrativos, procura resolver problemas sociais de forma inovadora e sustentável, com a finalidade de dar resposta aos grandes desafios sociais da atualidade, através da ação social na prevenção e no apoio nas diversas situações de fragilidade, exclusão ou carência humana, promovendo a inclusão, a integração social e o desenvolvimento local. O objetivo fundamental do presente trabalho, pretende verificar até que ponto as IPSS podem ser definidas como empreendedores sociais, através da prestação de serviços, nas variadas áreas à população local, de forma a alcançar o valor social. Neste estudo enveredou-se pela metodologia qualitativa, utilizando o método do estudo de caso único, recorrendo ao questionário como instrumento de recolha de dados numa instituição particular de solidariedade social do concelho da Maia. Deste estudo foi possível concluir a IPSS tem uma proximidade às populações, através das diversas valências vocacionadas para a resolução de problemas sociais emergentes, promovendo a inclusão a integração social, e alcançar o valor social. Assim, consideramos a IPSS estudada como sendo parte integrante e promotora do empreendedorismo social.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Introduction: In the XXI Century ’s Society the scientific investigation process has been growing steadily , and the field of the pharmaceutical research is one of the most enthusiastic and relevant . Here, it is very important to correlate observed functional alterations with possibly modified drug bio distribution patterns . Cancer, inflammation and inf ection are processes that induce many molecular intermediates like cytokines, chemokines and other chemical complexes that can alter the pharmacokinetics of many drugs. One cause of such changes is thought to be the modulator action of these complexes in t he P - Glyco p rotein activity, because they can act like inducers/inhibitors of MDR - 1 expression. This protein results from the expression of MDR - 1 gene, and acts as an ATP energy - dependent efflux pump, with their substrates including many drugs , like antiretrovirals, anticancers, anti - infectives, immunosuppressants, steroids or opioids . Objectives: Because of the lack of methods to provide helpful information in the investigation of in vivo molecular changes in Pgp activity during infection/infl ammation processes, and its value in the explanation of the altered drug pharmacokinetic, this paper want to evaluate the potential utility of 99m Tc - Sestamibi scintigraphy during this kind of health sciences investigation. Although the a im is indeed to create a technique to the in vivo study of Pgp activity, this preliminary Project only reaches the in vitro study phase, assumed as the first step in a n evaluation period for a new tool development. Materials and Methods: For that reason , we are performing in vitro studies of influx and efflux of 99m Tc - Sestamibi ( that is a substrate of Pgp) in hepatocytes cell line (HepG2). We are interested in clarify the cellular behavior of this radiopharmaceutical in Lipopolysaccharide(LPS) stimulated cells ( well known in vitro model of inflammation) to possibly approve this methodology. To validate the results, the Pgp expression will be finally evaluated using Western Blot technique. Results: Up to this moment , we still don’t have the final results, but we have already enough data to let us believe that LPS stimulation induce a downregulation of MDR - 1, and consequently Pgp, which could conduce to a prolonged retention of 99m Tc - Sestamibi in the inflamed cells . Conclusions: If and when this methodology demonstrate the promising results we expect, one will be able to con clude that Nuclear Medicine is an important tool to help evidence based research also on this specific field .

Relevância:

20.00% 20.00%

Publicador:

Resumo:

ECER 2014 "The Past, the Present and Future of Educational Research in Europe" will take place at the University of Porto from 1 - 5 September 2014.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Este artigo abordará as relações sociais dos bebês a partir da brincadeira, no sentido de apresentar orientações para a docência na educação infantil com crianças bem pequenas. O quadro teórico metodológico se situa na interlocução entre as áreas da Pedagogia da Infância e da Sociologia da Infância. Toma por base uma investigação sobre a ação social dos bebês na creche, que tinha como preocupação central conhecer os bebês e as suas ações no sentido de pensar a prática pedagógica junto das crianças bem pequenas. Trata-se de um estudo etnográfico com um grupo de bebês e profissionais, que com eles atuavam, numa creche em Braga. Para a compreensão da estruturação das ações e relações sociais pelos bebês foram desenvolvidas observações participantes, com registos em diário de campo e vídeo, o que permitiu uma aproximação bastante profícua das experiências cotidianas das crianças.