711 resultados para Intrinsically photosensitive


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This project aims to study the influence of information technology in the construction of new forms of citizenship. A large space as possible by the Internet allows the emergence of alternative news sources, as opposed to the means of mass communication. The research will take from the study of the news portal Choike.org. Maintained by civil society representatives, the website has a proposal to address topics that are infrequent in the media hegemony. To facilitate the study, we established a cut. Let's look at five bulletins Choike.org portal between the years 2005 and 2010 that address the issue of agrarian reform in Latin America, especially in Brazil. The issue is discussed by the media in general, however has more emphasis between the means of alternative journalism. For Choike.org portal, agrarian reform this intrinsically linked to social development. Therefore, this analysis seeks to highlight the role of new technologies as an important tool to aid discussion of the issue in the media as having specific focus to the issue of land reform

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Undocked institutions widely dilate the scope of time-space distancing, since the separation between these elements is crucial for the extreme dynamism of modernity. This separation is the prime condition of the process of disembedding, in which the displacement of social relations of local contexts of interaction and its redesign through indefinite extensions of time and space are favored. Therefore, there are two types of dislocated mechanisms intrinsically involved in the development of social modern institutions: symbolic tokens and expert systems. These mechanisms depend on reliability. Within this context, this present paper sees the professional life cycle of the teacher in the perspective of the expert system. It also sees the work stability of public servants in the symbolic token perspective, more specifically public teachers in Brazil. This paper also attempts to propose some reflections on what a disembedding in Brazilian education would mean and on how an eventual impasse between teachercentrism and studentcentrism would affect this process if necessary or desired, from one would understand by modernity.

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What is the role of qualitative data? How should mixed approaches be considered? Is it necessary to complement the quantitative approach by the qualitative approach (Maziére et al., 2010) or the opposite? How can these two approaches be combined in a Language Acquisition research? What are the possibilities of generalization that these approaches provide? Besides those necessary theoretical discussions, our starting point is a qualitative research on the acquisition of the plural morpheme in Brazilian Portuguese (BP) in children between 1 year 11 months old and 2 years 7 months old (Hilário, 2012), whose linguistic production is intrinsically connected to their dialogic aspect (Bakhtin & Vološinov, 1973) and to the interaction among interlocutors (Bruner, 2004; Vygotsky, 1986). In this research through the usage of a computational tool (CLAN) it is expected to have more visibility of the quantitative results even if they are in a qualitative approach. Although, it should be taken into account the fact that each approach can achieve valid and relevant results (Valsiner 2000), i.e., with any given method it is possible to reach a kind of generalization (statistical or analytical).

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Photodynamic therapy (PDT) is a promising method for localized and specific inactivation of fungi and bacteria. A nontoxic light-sensitive compound is taken up by cells, which are then exposed selectively to light, which activates toxicity of the compound. We investigated the potential of sublethal PDT using light-sensitive curcumin (CUR) in combination with blue (455 nm) light to promote reactive oxygen species (ROS) formation in the form of singlet oxygen and DNA damage of Candida albicans. Surprisingly, CUR-mediated PDT but also light alone caused significantly longer comet tails, an indication of DNA damage of C. albicans when compared with the negative control. The intracellular ROS production was also significantly higher for the group treated only with light. However, PDT compared to blue light alone significantly slowed DNA repair. Comet tails decreased during 30 min visualized as a 90% reduction in length in the absence of light for cells treated with light alone, while comet tails of cells treated with PDT only diminished in size about 45%. These results indicate that complex mechanisms may result in PDT in a way that should be considered when choosing the photosensitive compound and other aspects of the treatment design.

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The study presents the construction process of research methodology "Training in SUS Humanization: effects evaluation of training processes from institutional supporters on health productionin Rio Grande do Sul, Santa Catarina and São Paulo territories." There was a search for developing an appropriate evaluative practice to the training processes, a methodology that instead of evaluating on something, assessed along with the supporters who attended the training-intervention, a participatory methodology.Therefore, the constitution of the Research Interest Group was an eminent tool. Trained supporters comprised the research team to expand participatory possibilities of a large and dispersed group, producing interferences in the investigative process conduction, described and analyzed in the study.At the same time, their experiences interfered in the understandings they had until then about the intervention-training experiences and effects on their daily lives, after almost four years.Thus, the methodological approach was intrinsically linked to the construction of a subjectivity differentiated plan and necessarily collective, which shifted the position of supporters involved from mere data suppliers to a lateralityposition in relation to other actors.The trial afforded by participatory strategies allowed researchers and supporters to interfere and compose the evaluation scenario with remarkable performances throughout the investigative process.The survey configuration was like a bet on a given methodological architecture that, in seeking to overcome evaluator-evaluated logic produced information for (retro) feedingthe intervention triggered by it. In the formative dimension, it also went through working processes analyzed by supporters rescuing the indissoluble characteristic that health activities mobilize among intervening, training and reviewing.

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Pós-graduação em Direito - FCHS

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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We have previously shown that blue light eliminates the black-pigmented oral bacteria Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens, and Prevotella melaninogenica. In the present study, the in vitro photosensitivity of the above black-pigmented microorganisms and four Fusobacteria species (Fusobacterium nucleatum ss. nucleatum, F. nucleatum ss. vincentii, F. nucleatum ss. polymorphum, Fusobacterium periodonticum) was investigated in pure cultures and human dental plaque suspensions. We also tested the hypothesis that phototargeting the above eight key periodontopathogens in plaque-derived biofilms in vitro would control growth within the dental biofilm environment. Cultures of the eight bacteria were exposed to blue light at 455 nm with power density of 80 mW/cm(2) and energy fluence of 4.8 J/cm(2). High-performance liquid chromatography (HPLC) analysis of bacteria was performed to demonstrate the presence and amounts of porphyrin molecules within microorganisms. Suspensions of human dental plaque bacteria were also exposed once to blue light at 455 nm with power density of 50 mW/cm(2) and energy fluence of 12 J/cm(2). Microbial biofilms developed from the same plaque were exposed to 455 nm blue light at 50 mW/cm(2) once daily for 4 min (12 J/cm(2)) over a period of 3 days (4 exposures) in order to investigate the cumulative action of phototherapy on the eight photosensitive pathogens as well as on biofilm growth. Bacterial growth was evaluated using the colony-forming unit (CFU) assay. The selective phototargeting of pathogens was studied using whole genomic probes in the checkerboard DNA-DNA format. In cultures, all eight species showed significant growth reduction (p < 0.05). HPLC demonstrated various porphyrin patterns and amounts of porphyrins in bacteria. Following phototherapy, the mean survival fractions were reduced by 28.5 and 48.2 % in plaque suspensions and biofilms, respectively, (p < 0.05). DNA probe analysis showed significant reduction in relative abundances of the eight bacteria as a group in plaque suspensions and biofilms. The cumulative blue light treatment suppressed biofilm growth in vitro. This may introduce a new avenue of prophylactic treatment for periodontal diseases.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The intrinsically relativistic problem of spinless particles subject to a general mixing of vector and scalar kink- like potentials (similar to tanh gamma x) is investigated. The problem is mapped into the exactly solvable Sturm - Liouville problem with the Rosen - Morse potential and exact bounded solutions for particles and antiparticles are found. The behavior of the spectrum is discussed in some detail. An apparent paradox concerning the uncertainty principle is solved by recurring to the concept of effective Compton wavelength.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Economia - FCLAR

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The aim of this paper is to gather research information and studies posted about the importance of social environment in the development of symbolic systems on children. Languages verbal, visual and written are interrelated representation systems, although each one has its own characteristics and elements. The objective of this paper is to elucidate the importance of linking the various existing types of language and therefore the importance of a coordinate approach also in the teaching-learning situations of these systems. The work also intends to disclose how thin is the line that separates writing of drawing, both of them as representative systems. As well as to show how visual information and language are intrinsically linked as thought happens by the connections between them. The work includes the report of an activity with Japanese ideograms done in the author's teacher's training at formal education. It also approaches pictographic, creative and poetic aspects of ideograms that brings up new ways of thinking and representing symbolically just like the methods of artistic language