丝状加热面池沸腾临界热流尺度效应研究

本文以丝状加热表面上的池沸腾传热现象为主要研究对象，利用地面常重力实验，研究了不同热丝直径、不同过冷度下（(0～40℃）的丝状加热片面FC-72液体和丙酮液体的池沸腾传热特性。 本文利用自主研发的一套可控过冷度池沸腾实验设备，使用纯度为99.99%的铂丝同时作为加热元件和测温元件，加热丝直径分别为0.06mm、0.025mm、0.1mm，长度为30mm。实验采用控制加热电压按阶梯形式增长或下降（时间常数约20s）的稳态加热方式。 实验所得单相自然对流传热数据同Kuehn-Goldstein（1976）换热公式预测结果具有较高的一致性，说明实验设备可靠、实验数据可信。 实验过程中发现，在相同压力条件下，随着过冷度的增加，沸腾传热强化；CHF值在低过冷度时呈线性增加，然后增加趋势变缓。丙酮实验中，0.06mm热丝和0.1mm热丝在低过冷度(2.5～10℃)情况下都出现了从自然对流直接进入双膜态现象，不过，当降低加热电压时，膜态沸腾仍转化为核态沸腾，此时继续增高加热电压，沸腾曲线仍沿常规核态沸腾曲线上升至CHF后，再转换为膜态沸腾。对于同等直径热丝，无论核态沸腾或双膜态沸腾，在丙酮中所产生汽泡尺寸明显偏大。 过冷沸腾中，临界热流随过冷度的增加呈现出非线性依赖关系。在低过冷度线性区，FC-72中实验结果与几种低过冷度线性模型较一致；丙酮中实验结果 随 变化斜率明显高于几种低过冷度线性模型的预测，显示出对尺度的依赖关系。这说明在小Bond数时存在尺度效应对过冷度的影响，即对于小Bond数情况过冷度和尺度效应的耦合作用是非常重要的。 饱和沸腾中，FC-72和丙酮的CHF值随热丝直径的减小而不断增加，其中，FC-72的CHF数值尽管比LD模型预测结果略低，但定性地依然可用LD模型进行描述，尽管相比于LD模型原始的适用范围 已扩大了1~2个数量级；但丙酮的实验数据却远小于LD模型预测结果。综合分析表明，尽管热丝直径相同，但物性的差异使得FC-72和丙酮实验中的数据点分别处于不同的尺度特征区域，反映了小Bond数情形下分区准则的物性依赖性。

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EFTA 2009

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Bubble Behavior and Heat Transfer in Quasi-Steady Pool Boiling in Microgravity

Pool boiling of degassed FC-72 on a plane plate heater has been studied experimentally in microgravity. A quasi-steady heating method is adopted, in which the heating voltage is controlled to increase exponentially with time. Compared with terrestrial experiments, bubble behaviors are very different, and have direct effect on heat transfer. Small, primary bubbles attached on the surface seem to be able to suppress the activation of the cavities in the neighborhoods, resulting in a slow increase of the wall temperature with the heat flux. For the high subcooling, the coalesced bubble has a smooth surface and a small size. It is difficult to cover the whole heater surface, resulting in a special region of gradual transitional boiling in which nucleate boiling and local dry area can co-exist. No turning point corresponding to the transition from nucleate boiling to film boiling can be observed. On the contrary, the surface oscillation of the coalesced bubble at low subcooling may cause more activated nucleate sites, and then the surface temperature may keep constant or even fall down with the increasing heat flux. Furthermore, an abrupt transition to film boiling can also be observed. It is shown that heat transfer coefficient and CHF increase with the subcooling or pressure in microgravity, as observed in normal gravity.

Boiling heat transfer enhancement by using micro-pin-finned surface for electronics cooling

For efficiently cooling electronic components with high heat flux, experiments were conducted to study the flow boiling heat transfer performance of FC-72 over square silicon chips with the dimensions of 10 × 10 × 0.5 mm3. Four kinds of micro-pin-fins with the dimensions of 30 × 60, 30 × 120, 50 × 60, 50 × 120 μm2 (thickness, t × height, h) were fabricated on the chip surfaces by the dry etching technique for enhancing boiling heat transfer. A smooth surface was also tested for comparison. The experiments were made at three different fluid velocities (0.5, 1 and 2 m/s) and three different liquid subcoolings (15, 25 and 35 K). The results were compared with the previous published data of pool boiling. All micro-pin-fined surfaces show a considerable heat transfer enhancement compared with a smooth surface. Flow boiling can remarkably decrease wall superheat compared with pool boiling. At the velocities lower than 1 m/s, the micro-pin-finned surfaces show a sharp increase in heat flux with increasing wall superheat. For all surfaces, the maximum allowable heat flux, qmax, for the normal operation of LSI chips increases with fluid velocity and subcooling. For all micro-pin-finned surfaces, the wall temperature at the critical heat flux (CHF) is less than the upper limit for the reliable operation of LSI chips, 85◦C. The largest value of qmax can reach nearly 148 W/cm2 for micro-pin-finned chips with the fin height of 120 μm at the fluid velocity of 2 m/s and the liquid subcooling of 35 K. The perspectives for the boiling heat transfer experiment of the prospective micro-pin-finned sur- faces, which has been planned to be made in the Drop Tower Beijing/NMLC in the future, are also presented.

Molecular Modeling and Affinity Determination of scFv Antibody: Proper Linker Peptide Enhances Its Activity

One of existing strategies to engineer active antibody is to link VH and VL domains via a linker peptide. How the composition, length, and conformation of the linker affect antibody activity, however, remains poorly understood. In this study, a dual approach that coordinates molecule modeling, biological measurements, and affinity evaluation was developed to quantify the binding activity of a novel stable miniaturized anti-CD20 antibody or singlechain fragment variable (scFv) with a linker peptide. Upon computer-guided homology modeling, distance geometry analysis, and molecular superimposition and optimization, three new linker peptides PT1, PT2, and PT3 with respective 7, 10, and 15 residues were proposed and three engineered antibodies were then constructed by linking the cloned VH and VL domains and fusing to a derivative of human IgG1. The binding stability and activity of scFv-Fc chimera to CD20 antigen was quantified using a micropipette adhesion frequency assay and a Scatchard analysis. Our data indicated that the binding affinity was similar for the chimera with PT2 or PT3 and ~24-fold higher than that for the chimera with PT1, supporting theoretical predictions in molecular modeling. These results further the understanding in the impact of linker peptide on antibody structure and activity.

微重力池沸腾传热实验研究

本文实验研究了平板加热面FC-72液体的准稳态池沸腾传热现象,利用地面常重力实验、SJ-8卫星搭载微重力实验等手段,分析了不同重力、压力及过冷度条件下平板加热面上的池沸腾传热特性.微重力条件下,相近压力或过冷度时,传热系数和CHF随过冷度或压力增大而增大.相对常重力,传热曲线明显变缓,沸腾起始时的壁面过热度降低,CHF仅为常重力的40%或更低.