Sedimentary properties of salt wash sandstones as related to primary structures.

"Contract No. AT-30-1-1182."

The distinguished collection of western Americana (books, newspapers, and pamphlets, many relating to the Mormon Church) formed by the late Herbert S. Auerbach, Salt Lake City, Utah.

Part 1 sold Oct. 27-29, 1947; pt. 2, Oct. 25-26, 1948.

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketch], untitled. Ink and colored marker sketch on tracing paper, 12 x 24 1/4 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketch of Site Plan], untitled. Ink sketch with marker coloring on tracing paper, 12 x 25 1/2 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketch], untitled. Ink sketch on tracing paper, 12 x 22 1/2 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketch of Site Plan], untitled. Black and red ink and blue marker sketch on tracing paper, 12 x 26 1/4 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992, Salt Lake City, 1992-1996

[Conceptual Sketch of Site Plan], untitled. Ink sketch with marker coloring on tracing paper, 12 x 25 1/2 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketches], untitled. Ink sketches with marker coloring on tracing paper, 18 x 28 1/2 inches [from photographic copy by Lance Burgharrdt]

University of Utah J. Willard Marriott Library Addition, Salt Lake City, 1992-1996

[Conceptual Sketches], untitled. Ink sketches with marker coloring on tracing paper, initialed, 12 x 28 1/2 inches [from photographic copy by Lance Burgharrdt]

Military implications of the Treaty on the limitation of strategic offensive arms and protocol thereto (SALT II Treaty) : hearings before the Committee on Armed Services, United States Senate, Ninety-sixth Congress, first session ...

Includes indexes.

Improving constraints on the sources and distribution of sea salt aerosols in polar regions

Thesis (Master's)--University of Washington, 2016-06

IRS-1 regulation in health and disease

The global incidence of diabetes is increasing at epidemic rates. Estimates suggest there are currently 150 million people with diabetes and this number is expected to double in the next 20 years. Type 2 diabetes accounts for 95% of all cases and is characterized in part by impaired sensitivity to insulin or 'insulin resistance'. Defects in the insulin signalling pathways underpin this resistance. In the current article we discuss the regulation of Insulin Receptor Substrate-1 (IRS-1), a protein that plays a pivotal role in insulin signalling and whose function is impaired in subjects with insulin resistance. Coordination of IRS-1 function is multi-faceted, involving phosphorylation of IRS-1 at multiple serine/threonine residues. This controls many aspects of IRS-1, including its interaction with the insulin receptor and subsequent tyrosine phosphorylation, as well as its subcellular distribution and targeting for degradation by the proteasome. Such tight control ensures appropriate transduction and attenuation of the insulin signal, thereby regulating insulin action in healthy individuals. Emerging evidence indicates that `diabetogenic factors' associated with insulin resistance, such as TNFalpha and elevated circulating fatty acids, impact on insulin signalling at the level of IRS-1 serine/threonine phosphorylation. The expression and/or activity of several kinases, such as IkappaB kinase beta (IKKbeta) and salt-induced kinase 2 (SIK2), and the phosphorylation of IRS-1 at key sites, such as Ser307 and Ser789, are increased in states of insulin resistance. Identifying the pathways by which such factors activate these and other kinases, and de. ning the precise roles of specific serine/threonine phosphorylation events in IRS-1 regulation, represent important goals which may eventually provide a rationale for therapeutic intervention.

L-arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats

Nitric oxide (NO) is essential for normal function of the cardiovascular system. This study has determined whether chronic administration of L-arginine, the biological precursor of NO, attenuates the development of structural and functional changes in hearts and blood vessels of deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Uninephrectomized rats treated with DOCA (25 mg every 4th day sc) and 1% NaCl in the drinking water for 4 wk were treated with L-arginine (5% in food, 3.4 +/- 0.3 g.kg body wt(-1).day(-1)). Changes in cardiovascular structure and function were determined by echocardiography, microelectrode studies, histology, and studies in isolated hearts and thoracic aortic rings. DOCA-salt hypertensive rats developed hypertension, left ventricular hypertrophy with increased left ventricular wall thickness and decreased ventricular internal diameter, increased inflammatory cell infiltration, increased ventricular interstitial and perivascular collagen deposition, increased passive diastolic stiffness, prolonged action potential duration, increased oxidative stress, and inability to increase purine efflux in response to an increased workload. L-Arginine markedly attenuated or prevented these changes and also normalized the reduced efficacy of norepinephrine and acetylcholine in isolated thoracic aortic rings of DOCA-salt hypertensive rats. This study suggests that a functional NO deficit in blood vessels and heart due to decreased NO synthase activity or increased release of reactive oxygen species such as superoxide may be a key change initiating many aspects of the cardiovascular impairment observed in DOCA-salt hypertensive rats. These changes can be prevented or attenuated by administration of L-arginine.

Salt diffusion and distribution in meat studied by Na-23 nuclear magnetic resonance imaging and relaxometry

This study introduces the use of combined Na-23 magnetic resonance imaging (MRI) and Na-23 NMR relaxometry for the study of meat curing. The diffusion of sodium ions into the meat was measured using Na-23 MRI on a 1 kg meat sample brined in 10% w/w NaCl for 3-100 h. Calculations revealed a diffusion coefficient of 1 x 10(-5) cm(2)/s after 3 h of curing and subsequently decreasing to 8 x 10(-6) cm(2)/s at longer curing times, suggesting that changes occur in the microscopic structure of the meat during curing. The microscopic mobility and distribution of sodium was measured using Na-23 relaxometry. Two sodium populations were observed, and with increasing length of curing time the relaxation times of these changed, reflecting a salt-induced swelling and increase in myofibrillar pore sizes. Accordingly, the present study demonstrated that pore size and thereby salt-induced swelling in meat can be assessed using Na-23 relaxometry.

Control of ordered structure and morphology of large-pore periodic mesoporous organosilicas by inorganic salt

Highly ordered rodlike periodic mesoporous organosilicas (PMO) were successfully synthesized using 1.2-bis(trimethoxysilyl)ethane as an precursor and triblock copolymer P123 as a template at low acid concentration and in the presence of inorganic salts (KCl). The role of acid and salt as well as the effects of synthesis temperature and reactant mole ratio in the control of morphology and the formation of ordered mesostructure was systematically examined. It was found that the addition of inorganic salt can dramatically expand the range of the synthesis parameters to produce highly ordered PMO structure and improve the quality of PMO materials. The morphology of PMOs was significantly dependent on the induction time for precipitation. The uniform PMO rods can only be synthesized in a narrow range of acid and salt concentrations. The results also show that the optimized salt concentration (I M) and low acidity (0.167 M) were beneficial to the formation of not only highly ordered mesostructure but also rodlike morphology. Increasing acidity resulted in fast hydrolysis reaction and short rod or plate-like particles. Highly ordered rod can also be prepared at low temperature (35 degrees C) with high salt amount (1.5 M) or high temperature (45 degrees C) with low salt amount (0.5 M). Optimum reactant molar composition at 40 degrees C is 0.035P123:8KCl:1.34HCI:444H(2)O:1.0bis(trimethoxysilyl)ethane. Lower or higher SiO2/PI23 ratio led to the formation of uniform meso-macropores or pore-blocking effect. (c) 2005 Elsevier Inc. All rights reserved.