998 resultados para critérios de formulação


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Gymnema sylvestre extract (GSE) is a plant product widely used as an adjuvant in the treatment of diabetes mellitus and commercially available as a powder. Owing to its low flowability, the manufacturing of hard gelatin capsules containing GSE faces specific problems. The purpose of this study was to investigate the best excipient (starch, lactose or microcrystalline cellulose) for hard gelatin capsules containing GSE. The technological properties such us bulk density (ρβ); tapped density (ρt); inter-particle porosity (Ie); Carr index (CI); Hausner ratio (HR); loss on drying (%LOD) and particle size distribution (%Pf) of the various GSE mixtures were investigated with the aim of identifying the best excipient. The need for lubricants (talc/magnesium stearate) was also assessed. GSE was characterized as a fine powder with more than 50% of its particles between 0.149mm to 0.250mm; furthermore, CI=25.6%; RH=1.3 and Ie = 25.6% and, as expected with such properties, it showed poor flowability. All the excipients investigated were able to change the technological properties of GSE and the powder mixture containing microcrystalline cellulose gave the best results.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This article aims to present a list of the main influences experimented by architects and urbanists to formulate an urban thought of Sao Paulo City. This way, it will be discussed the main issues raised between the first decades of the XX Century until the 1950s, trying to foresee how the engineers and architects worked to incorporate the urbanistic proposals from Europe and the United States. On the first three sections of this article, it will be presented the concepts that effectively impacted the paulista urban thought of the first half of the XX Century: Sanitarism, the pendulum design: between the Mesologic Theory and the Microbian Theory; Camillo Sitte's historicist formulation; Howard Garden Town and the French experience. Our analysis was formulated by having as a reference a broad and systematic literature, documents stored at Arquivo Histórico Municipal de Araraquara (SP), visits to Faculdade de Arquitetura e Urbanismo da USP Library and to Faculdade de Ciências e Letras da Unesp, Araraquara. The analysis shows that two urbanistic planner streams that happened in São Paulo State were clearly influenced by the conceptions that led the urbanistic debates in the first half of the XX Century. So, these conceptions compose a painting of the urban interventions in São Paulo City.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The present study aimed to determine which leave will be displayed and the time of collection of this leave. The treatments consisted on five doses of nitrogen, four times for collection sampling and three types of leaves, arranged in a randomized block design with three repetitions, totalizing one hundred and forty-four experimental units. The leaves collections took place every fifteen days at thirty, forty-five, sixty and seventy five days after budbreak (DAB), collecting the laminated / compound young leaf (first leave), newly mature (second leave) and the mature leave (third leave) from the set of terminal leaflets. For this was installed an experiment with the culture of potato (cv. Atlantic), in Barretos/SP, the period of march the june of 2010. According to this data collected in this study, the best time for collecting the leaves is at 30 days after the budbreak of the potato cultivation containing nitrogen concentrations in the leaves minus heterogeneous of plants from a fraction to another and with values R2 = 0.98 being higher to the all times of harvests. To the diagnostic leaf, the highest determination coefficient was observed in the newly mature (second leaf) with R2 = 0.98. It can be observed that the highest levels of nitrogen were found on the first leaf (39.01 kg-1). Nevertheless, the values were very heterogeneous and did not fit the curve being the second leave (newly mature) the one that best represents the nutritional status of the plant. Therefore the recommendation for nutritional diagnosis will collect the recently matured leaves (2nd leaf) 30 days after budbreak.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)