997 resultados para antagonist V-2
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El segundo volumen, titulado Educación Empresarial, está compuesto por siete artículos: Allan Gibb propone un nuevo modelo educativo que desecha la idea de que existe una solución “única” aplicable a todos los grupos; Rodrigo Varela comparte el nuevo modelo educativo que ha implementado el CDEE-Icesi y que le valió la distinción de USASBE “2010 Global Entrepreneurship Education Award”, basado en el desarrollo de las competencias empresariales; Yvon Gasse y Maripier Tremblay presentan los resultados de una investigación intercultural (Canadá, Francia, Argelia, Colombia) que estudia el tema de la Intención Empresarial en estudiantes universitarios ; Fernando Dolabella y Louis Jacques Filion muestra la excelente conceptualización y operación de la pedagogía empresarial en Brasil; George Solomon hace un profundo análisis de las cercanías, acuerdos y confusiones que se dan entre la educación para la creación de nuevas empresas y la educación para el desarrollo de la Pyme; José Romaguera, explica cómo se puede implementar un proceso que genere estímulos positivos para la creación de empresa entre la población joven; Alain Fayone y Olivier Toutain ilustran cómo la educación empresarial tiene que ser integradora y práctica.
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This publication is volume 2, issue 1 of the University of South Carolina Publications. Series III. Biology. on taxonomic studies of the flora and fauna of South Carolina.
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This publication is volume 2, issue 2 of the University of South Carolina Publications. Series III. Biology. on taxonomic studies of the flora and fauna of South Carolina.
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This publication is volume 2, issue 4 of the University of South Carolina Publications. Series III. Biology. on taxonomic studies of the flora and fauna of South Carolina.
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This publication is volume 2, issue 3 of the University of South Carolina Publications. Series III. Biology. on taxonomic studies of the flora and fauna of South Carolina.
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From Penghidoepan Series, Taon V, No. 59, 15 Dec 1929
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In this study we investigated the influence of d(CH2)(5)-Tyr(Me)-[Arg(8)]vasopressin (AAVP) and [adamanteanacetyl(1),0-ET-DTyr(2), Val(4), aminobutyryl(6), Arg(8,9)]-[Arg(8)]vasopressin (ATAVP), which are antagonists of vasopressin V-1 and V-2 receptors, and the effects of losartan, a selective angiotensin AT(1) receptor antagonist, and CGP42112A, a selective AT(2) receptor antagonist, injected into the lateral septal area (LSA) on thirst and hypertension induced by [Arg(8)]vasopressin (AVP). AAVP and ATAVP injected into the LSA reduced the drinking responses elicited by injecting AVP into the LSA. Both the AT(1) and AT(2) ligands administered into the LSA elicited a concentration-dependent decrease in the water intake induced by AVP injected into the LSA, but losartan was more effective than CGP42112A. The increase in MAP, due to injection of AVP into the LSA, was reduced by prior injection of AAVP from 18 +/- 1 to 6 +/- 1 mm Hg. Losartan injected into the LSA prior to AVP reduced the increase in MAP to 7 +/- 0.8 mm Hg. ATAVP and CGP42112A produced no changes in the pressor effect of AVP. These results suggest that the dipsogenic effects induced by injecting AVP into the LSA were mediated primarily by AT(1) receptors. However, doses of losartan were more effective when combined with CGP42112A than when given alone, suggesting that the thirst induced by AVP injections into LSA may involve activation of multiple AVP and angiotensin II receptor subtypes. The pressor response of AVP was reduced by losartan and by AAVP. CGP42112A and ATAVP did not change the AVP pressor response. These results suggest that facilitator effects of AVP on water intake are mediated through the activation of V-1 receptors and that the inhibitory effect requires V-2 receptors. The involvement of AT(1) and AT(2) receptors can be postulated. Based on the present findings, we suggest that the AVP in the LSA may play a role in the control of water and arterial blood pressure balance. (C) 2004 Elsevier B.V. All rights reserved.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)