EORTC Radiation Oncology Group quality assurance platform: establishment of a digital central review facility.

OBJECTIVE: Quality assurance (QA) in clinical trials is essential to ensure treatment is safely and effectively delivered. As QA requirements have increased in complexity in parallel with evolution of radiation therapy (RT) delivery, a need to facilitate digital data exchange emerged. Our objective is to present the platform developed for the integration and standardization of QART activities across all EORTC trials involving RT. METHODS: The following essential requirements were identified: secure and easy access without on-site software installation; integration within the existing EORTC clinical remote data capture system; and the ability to both customize the platform to specific studies and adapt to future needs. After retrospective testing within several clinical trials, the platform was introduced in phases to participating sites and QART study reviewers. RESULTS: The resulting QA platform, integrating RT analysis software installed at EORTC Headquarters, permits timely, secure, and fully digital central DICOM-RT based data review. Participating sites submit data through a standard secure upload webpage. Supplemental information is submitted in parallel through web-based forms. An internal quality check by the QART office verifies data consistency, formatting, and anonymization. QART reviewers have remote access through a terminal server. Reviewers evaluate submissions for protocol compliance through an online evaluation matrix. Comments are collected by the coordinating centre and institutions are informed of the results. CONCLUSIONS: This web-based central review platform facilitates rapid, extensive, and prospective QART review. This reduces the risk that trial outcomes are compromised through inadequate radiotherapy and facilitates correlation of results with clinical outcomes.

Breast and cervical cancer screening programme implementation in 16 countries.

OBJECTIVES: There is a continuing need to monitor and evaluate the impact of organized screening programmes on cancer incidence and mortality. We report results from a programme assessment conducted within the International Cancer Screening Network (ICSN) to understand the characteristics of cervical screening programmes within countries that have established population-based breast cancer screening programmes. METHODS: In 2007-2008, we asked 26 ICSN country representatives to complete a web-based survey that included questions on breast and cervical cancer screening programmes. We summarized information from 16 countries with both types of organized programmes. RESULTS: In 63% of these countries, the organization of the cervical cancer screening programme was similar to that of the breast cancer screening programme in the same country. There were differences in programme characteristics, including year established (1962-2003 cervical; 1986-2002 breast) and ages covered (15-70+ cervical; 40-75+ breast). Adoption of new screening technologies was evident (44% liquid-based Pap tests; 13% human papillomavirus (HPV)-triage tests cervical; 56% digital mammography breast). There was wide variation in participation rates for both programme types (<4-80% cervical; 12-88% breast), and participation rates tended to be higher for cervical (70-80%) than for breast (60-70%) cancer screening programmes. Eleven ICSN member countries had approved the HPV vaccine and five more were considering its use in their organized programmes. CONCLUSION: Overall, there were similarities and differences in the organization of breast and cervical cancer screening programmes among ICSN countries. This assessment can assist established and new screening programmes in understanding the organization and structure of cancer screening programmes.

Campus formatiu virtual : CampusNET

L'objectiu del projecte és desenvolupar una plataforma de formació online. Es dissenyarà una aplicació web que permeti, per una banda, la gestió i administració de cursos i per altra banda, l'accés dels clients als cursos contractats.

Campus formatiu

Desenvolupament d'una plataforma de formació online amb ASP.NET.

Estudi de com OWL amplia la funcionalitat d'RDF i aquest, a la seva vegada, d'XML

Aquest document explica com és aquesta web actual o sintàctica, basada en llenguatge HTML, i perquè no treu més profit de la ingent quantitat d'informació que conté. També explica d'una manera detallada quina és l'alternativa que la comunitat informàtica proposa per tal de superar aquests inconvenients.

sisCave : Sistema de Catalogació de Cavitats

Aquest treball de final de carrera pretén cobrir una necessitat divulgativa del món de l'espeleologia, proporcionant al col·lectiu espeleològic una aplicació basada en web que permeti publicar, de forma cooperativa, ressenyes de cavitats incorporant dades textuals, fotografies, topografies i mapes d'ubicació.El projecte s'ha desenvolupat com a Treball de Final de Carrera de l'àrea J2EE de l'Enginyeria Tècnica en Informàtica de Gestió. La seva implementació, per tant, està basada en Programació Orientada a Objectes amb llenguatge Java i tecnologies J2EE.

Reducing young people's drinking

This series of Good Practice Guides is designed to share important information about health inequalities and some of the evidence-based measures that can be taken to reduce the stark differences in health and wellbeing within populations. The conditions in which people are born, grow, live, work and age can lead to health inequalities the unfair and avoidable differences in health status. Actions to tackle health inequalities demand the efforts of government, statutory organisations, and community, voluntary and private sectors. This Good Practice Guide to reducing young people's drinking is one of a series designed to capture information about health inequalities and highlight evidence-based interventions and key actions for improvement across sectors.This resource was contributed by The National Documentation Centre on Drug Use.

Good Practice Guides: Reducing young people's drinking

Actions to tackle health inequalities demand the efforts of government, statutory organisations, and community, voluntary and private sectors. This Good Practice Guide to reducing young people's drinking is one of a series designed to capture information about health inequalities and highlight evidence-based interventions and key actions for improvement across sectors.This resource was contributed by The National Documentation Centre on Drug Use.

Survey of Lifestyle, Attitudes and Nutrition in Ireland. Mental Health and Social Well-being Report

SĹN 2007: Older People, Loneliness and Social Support to Mental HealthSĹN, the national Survey of Lifestyle, Attitudes and Nutrition, shows that most Irish adults have a reasonably high level of positive mental health. It is the largest national survey on positive and negative mental health and social well-being in the Irish adult population.��One finding highlights the significance of loneliness and social support to mental health. Finding reveal that 14% of respondents reported being often lonely in the last four weeks, with women, older people and respondents in lower social class groups reporting high levels of loneliness. The SĹN report indicates that being widowed and not being in paid employment are the strongest overall predictors of loneliness. Respondents who are widowed are about five times more likely to feel lonely than those who are married or cohabiting, while 17% of respondents aged 65 and over report being often lonely.��SLAN 2007 highlights the significance of loneliness and social support to mental health. It proposes community-based interventions, including community development approaches and strategies to promote community involvement as a way to tackle such social and health inequities at local level. The report also highlights the importance of implementing the recommendations of the policy document A Vision for Change. It says that protection and promotion of the future health and well-being of the Irish population requires the implementation of effective cross-sectoral policies that will help create and maintain a mentally healthy society, with consequent health, economic and social benefits for all.����SLAN is commissioned by the Department of Health and Children and involved face-to-face interviews with 10,364 respondents aged 18 years and over.��

The Eukaryotic Promoter Database EPD: the impact of in silico primer extension.

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, experimentally defined by a transcription start site (TSS). There may be multiple promoter entries for a single gene. The underlying experimental evidence comes from journal articles and, starting from release 73, from 5' ESTs of full-length cDNA clones used for so-called in silico primer extension. Access to promoter sequences is provided by pointers to TSS positions in nucleotide sequence entries. The annotation part of an EPD entry includes a description of the type and source of the initiation site mapping data, links to other biological databases and bibliographic references. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis. Web-based interfaces have been developed that enable the user to view EPD entries in different formats, to select and extract promoter sequences according to a variety of criteria and to navigate to related databases exploiting different cross-references. Tools for analysing sequence motifs around TSSs defined in EPD are provided by the signal search analysis server. EPD can be accessed at http://www.epd. isb-sib.ch.

Projecte Nàstic Store : Tenda virtual del Club Gimnàstic de Tarragona.

El treball de final de carrera s'ha basat en l'anàlisi, disseny i la seva posterior implementació d'un programari web basat en una web site i una aplicació que configuren la tenda virtual que era l'objectiu final d'aquest projecte.

Ús de l'entorn virtual LAMS per a la creació de seqüències didàctiques col·laboratives i personalitzables

LAMS (Learning Activity Management System), com a projecte de programari lliure basat en tecnologies web, va ser alliberat a la comunitat d'usuaris i desenvolupadors el Febrer del 2005, des d'aquesta data fins avui s'han produït una sèrie d'avenços i innovacions que ha permès fer extensiu l'ús d'aquest entorn a persones amb pocs coneixements de programació i relacionades amb la pedagogia i el disseny instruccional. La investigació portada a terme ha permès a un grup d'investigadors de la Universitat Oberta de Catalunya (UOC) aprofundir en el disseny instruccional de seqüències didàctiques amb LAMS potenciant dos aspectes clau, el treball col·laboratiu virtual i també la personalització de l'aprenentatge per part de l'estudiant. Durant la recerca es va elaborar una guia de disseny instruccional per implementar activitats didàctiques amb LAMS que tinguin les dos característiques anteriorment descrites, i va servir com a referència per portar a terme una prova pilot amb estudiants de la universitat per tal de valorar el seu grau de satisfacció amb el procés d'aprenentatge mitjançant l'ús de l'entorn virtual LAMS. L'estudi revela un elevat grau de satisfacció en quant als dos factors examinats, d'una banda, els estudiants consideren que les activitats proporcionades afavoreixen la construcció de coneixement col·lectiu i, d'altra banda, també consideren que és molt positiu que es pugui personalitzar l'aprenentatge mitjançant l'elecció de les activitats a fer per adquirir una competència específica.

Building Capacity in Developing Countries : OER for Food Safety

The Food Safety Knowledge Network (FSKN) was developed through the collaboration of Michigan State University and a professional network of international food industry retailers and manufacturers. The key objective of the FSKN project is to provide technical resources, in a cost effective way, in order to promote food safety in developing countries and for small and less developed companies. FSKN uses a competency based model including a framework, OERs, and assessments. These tools are being used to support face-to-face training, fully online training, and to gauge the learning outcomes of a series of pilot groups which were held in India, Egypt, and China.

Free Technology Academy : a Joint Venture of Free Software and OER

The decision to publish educational materials openly and under free licenses brings up the challenge of doing it in a sustainable way. Some lessons can be learned from the business models for production, maintenance and distribution of Free and Open Source Software. The Free Technology Academy (FTA) has taken on these challenges and has implemented some of these models. We briefly review the FTA educational programme, methodologies and organisation, and see to which extent these models are proving successful in the case of the FTA.

Big and Little OER

Much of the attention around OERs has been on institutional projects which make explicit learning content available. These can be classified as 'big OER' but another form of OER is that of small scale, individually produced resources using web 2.0 type services, which are classified as 'little OER'. This paper examines some of the differences between the use of these two types of OER to highlight issues in open education. These include attitudes towards reputation, the intentionality of the resource, models of sustainability, the implicit affordances of resources and the context of their hosting sites.