No War, No Peace: Northern Ireland after the Agreement

In 1998 a historic agreement, commonly known as the Belfast or Good Friday Agreement, formed the basis of a negotiated settlement for the future of Northern Ireland. Since that time the level of violence in Northern Ireland has reduced but many problematic issues related to governance, sectarianism, and community relations remain on the political agenda and have destabilized the post-peace accord environment. Many of these issues can be viewed as either causes or consequences of the protracted conflict in Northern Ireland. This special issue examines some of these issues from a political psychology perspective. Economic, political, social, and psychological factors that have supported and hindered progress towards peace and stability are considered. While the paramilitary ceasefires have remained intact and certain aspects of life in Northern Ireland have been transformed, the road to peace has been hindered by both political and psychological intransigence. This paper offers an opportunity to reevaluate conceptualisations of conflict and its management in chronic situations, where divisions are deeply embedded within societal structures and relationships, and consider factors that may act as barriers to the development of a lasting peace.

Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3) GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-diabetes.

Glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide [GIP]) is an important incretin hormone secreted by endocrine K-cells in response to nutrient ingestion. In this study, we investigated the effects of chemical ablation of GIP receptor (GIP-R) action on aspects of obesity-related diabetes using a stable and specific GIP-R antagonist, (Pro3)GIP. Young adult ob/ob mice received once-daily intraperitoneal injections of saline vehicle or (Pro3)GIP over an 11-day period. Nonfasting plasma glucose levels and the overall glycemic excursion (area under the curve) to a glucose load were significantly reduced (1.6-fold; P <0.05) in (Pro3)GIP-treated mice compared with controls. GIP-R ablation also significantly lowered overall plasma glucose (1.4-fold; P <0.05) and insulin (1.5-fold; P <0.05) responses to feeding. These changes were associated with significantly enhanced (1.6-fold; P <0.05) insulin sensitivity in the (Pro3)GIP-treated group. Daily injection of (Pro3)GIP reduced pancreatic insulin content (1.3-fold; P <0.05) and partially corrected the obesity-related islet hypertrophy and ß-cell hyperplasia of ob/ob mice. These comprehensive beneficial effects of (Pro3)GIP were reversed 9 days after cessation of treatment and were independent of food intake and body weight, which were unchanged. These studies highlight a role for GIP in obesity-related glucose intolerance and emphasize the potential of specific GIP-R antagonists as a new class of drugs for the alleviation of insulin resistance and treatment of type 2 diabetes.

Assessing the Impact of Shipping Vessel Noise on Humpback Whales

The ocean is a hub of noise. Bioacoustic noise, noise from precipitation and wind, and noise from oceanic shelf slides and other geologic processes have occurred consistently as marine species have evolved over time. However, with the discovery of oceanic oil and gas reserves, submarine systems, ship propulsion and the emergence of global trade, anthropogenic sources of sound have added significant quantities of sound to the oceanic system. Shipping has been found to be the largest input of low-frequency anthropogenic noise and Humpback Whales (Megaptera novaengliae), known to be the most vocal marine species, have an auditory sensitivity that falls within the range of frequencies emitted by shipping vessels. As Humpback Whales are heavily dependent on vocalizations, for reasons relatively unconfirmed, a better understanding of why they sing and how their communication is being impacted by vessel noise is critical. Evaluating existing literature both on Humpback behavior and communication, the mechanics of their communication, sound emissions from modern ships, oceanic sound transmission, and studies regarding Humpback's exposure to other sources of low-frequency anthropogenic noise, it is clear that more research is needed to draw any causational conclusions between vessel noise and detrimental impacts on Humpback Whales. With a projected increase in global consumption and vessel traffic, there is an urgent need for further research exploring shipping noise impacts and behavioural alterations of Humpbacks. Existing research has shown changes in Humpback communication when exposed to low-frequency sonar noise, however few studies have been conducted on their communication when in close proximity to shipping vessels. In order for the impacts to be properly assessed, preliminary understanding of humpback communication, their auditory thresholds and more studies between vessel noise exposure and Humpback Whale behavior must be conducted.