Anatomical variations of the celiac trunk and hepatic arterial system: an analysis using multidetector computed tomography angiography

Abstract Objective: To analyze the prevalence of anatomical variations of celiac arterial trunk (CAT) branches and hepatic arterial system (HAS), as well as the CAT diameter, length and distance to the superior mesenteric artery. Materials and Methods: Retrospective, cross-sectional and predominantly descriptive study based on the analysis of multidetector computed tomography images of 60 patients. Results: The celiac trunk anatomy was normal in 90% of cases. Hepatosplenic trunk was found in 8.3% of patients, and hepatogastric trunk in 1.7%. Variation of the HAS was observed in 21.7% of cases, including anomalous location of the right hepatic artery in 8.3% of cases, and of the left hepatic artery, in 5%. Also, cases of joint relocation of right and left hepatic arteries, and trifurcation of the proper hepatic artery were observed, respectively, in 3 (5%) and 2 (3.3%) patients. Mean length and caliber of the CAT were 2.3 cm and 0.8 cm, respectively. Mean distance between CAT and superior mesenteric artery was 1.2 cm (standard deviation = 4.08). A significant correlation was observed between CAT diameter and length, and CAT diameter and distance to superior mesenteric artery. Conclusion: The pattern of CAT variations and diameter corroborate the majority of the literature data. However, this does not happen in relation to the HAS.

Variations of plasmid content in Rickettsia felis.

BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mostly due to the contamination of an initial R. felis culture by R. typhi. However, the first stable culture of R. felis allowed its precise phenotypic and genotypic characterization, and demonstrated that this species belonged to the spotted fever group rickettsiae. Later, its genome sequence revealed the presence of two forms of the same plasmid, physically confirmed by biological data. In a recent article, Gillespie et al. (PLoS One. 2007;2(3):e266.) used a bioinformatic approach to refute the presence of the second plasmid form, and proposed the creation of a specific phylogenetic group for R. felis. METHODOLOGY/PRINCIPAL FINDINGS: In the present report, we, and five independent international laboratories confirmed unambiguously by PCR the presence of two plasmid forms in R. felis strain URRWXCal(2) (T), but observed that the plasmid content of this species, from none to 2 plasmid forms, may depend on the culture passage history of the studied strain. We also demonstrated that R. felis does not cultivate in Vero cells at 37 degrees C but generates plaques at 30 degrees C. Finally, using a phylogenetic study based on 667 concatenated core genes, we demonstrated the position of R. felis within the spotted fever group. SIGNIFICANCE: We demonstrated that R. felis, which unambiguously belongs to the spotted fever group rickettsiae, may contain up to two plasmid forms but this plasmid content is unstable.

Aquaculture production in areas with high seasonal temperature variations: Development of planning tools

Postprint (published version)

Copy number variations of colorectal cancer by whole exome sequencing data

Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of cancer death worldwide. About 85% of the cases of CRC are known to have chromosomal instability, an allelic imbalance at several chromosomal loci, and chromosome amplification and translocation. The aim of this study is to determine the recurrent copy number variant (CNV) regions present in stage II of CRC through whole exome sequencing, a rapidly developing targeted next-generation sequencing (NGS) technology that provides an accurate alternative approach for accessing genomic variations. 42 normal-tumor paired samples were sequenced by Illumina Genome Analyzer. Data was analyzed with Varscan2 and segmentation was performed with R package R-GADA. Summary of the segments across all samples was performed and the result was overlapped with DEG data of the same samples from a previous study in the group1. Major and more recurrent segments of CNV were: gain of chromosome 7pq(13%), 13q(31%) and 20q(75%) and loss of 8p(25%), 17p(23%), and 18pq(27%). This results are coincident with the known literature of CNV in CRC or other cancers, but our methodology should be validated by array comparative genomic hybridisation (aCGH) profiling, which is currently the gold standard for genetic diagnosis of CNV.

"Quería crear un nuevo cosmos" : Aleksandr Scriabin y su sonata para piano nº 9

A partir de l’estudi general de l’obra d’Aleksandr Scriabin i a partir de l’anàlisi particular de la Sonata núm. 9 així com de les distintes influències que va tenir, el treball pretén fer una valoració de com caldria interpretar la Sonata núm. 9. És per això que hom fa una introducció general a la vida de Scriabin i el situa en el seu context històric; estudia el seu interès per la filosofia i com aquesta va influir en la seva obra. Alhora hom analitza la faceta de Scriabin com a pianista i en revisa l’obra com a compositor. La segona part del treball, pròpiament analítica, entra en la qüestió de les sonates i la importància que adquireixen en tota la seva obra per tal de centrar-se, en el darrer punt, en la Sonata núm. 9 i l’enfocament interpretatiu que podria tenir. Aquí, a partir del que prèviament s’ha estudiat, hom proposa una possibilitat interpretativa. En relació a aquest punt es comparen interpretacions de diversos pianistes.

Variations on "Mein junges Leben hat ein End"

Soitinnus: Urut.

Quintet in F minor, op. 34

The Hollywood String Quartet: Slatkin, Felix, viulu ; Shure, Paul, viulu ; Robyn, Paul, alttoviulu ; Aller, Eleanor, sello.

Variations on "Unter der Linden grüne"

Soitinnus: Urut.

Partita [!] in e minor for violin and piano

Äänitetty: 6.8.1952, New York, Columbia’s 30th Street studio.

Variations from Partita "Was Gott tut, das ist wohlgetan"

Soitinnus: Urut.