Social cognitive theory and factors associated with Mexican-American parents' beliefs, attitudes and practices regarding communication with their adolescent children about sex

Latinos have the highest teen birth rate nationally. Cameron County, Texas is primarily Latino (Mexican-American). This mixed-method study (n=43) examines Mexican-American parents of adolescents' beliefs, attitudes and practices regarding communication with their adolescent children about sex. Social Cognitive Theory (SCT) constructs self-efficacy, behavioral determinism, environment, outcome expectations and reciprocal determinism can be influences on frequency and quality of parent-adolescent sex communication.^ This study describes Mexican-American parents' of adolescents recollections of their own experiences associated with learning about sexuality. It also examines the attitudes and practices regarding communication about sex and the self-efficacy and behavioral capability of participants to teach their adolescent children about sex and sexually transmitted infections. ^ Negative childhood experiences (shame, lies and trauma) of the parents in this study played a key role in terms of their desire to communicate more comprehensively about sexuality with their own children than did their parents. While participants' reported low self-efficacy and behavioral capability to communicate with their adolescent children about sex, they reported relatively high frequency and quality of communication, with 75% of participants receiving a high quality score and over 44% reporting frequent communication with their adolescent children about sex. A Chi square analysis and Fisher's Exact Score revealed no association between acculturation status, gender or having a child who has mothered/fathered a baby and the frequency or quality of communication about sex with adolescent children. Study participants also gave specific recommendations for method, content and setting of sex education for their children and themselves. Promotora delivery of information and education in a comfortable, culturally appropriate neighborhood setting, as well as parent –child learning sessions were identified as possible approaches to address improve self-efficacy and behavioral capability of parents communicating with their adolescent children about sex.^ The results of this analysis provide public health practitioners and interested community entities data to identify and develop interventions that use a theoretical, evidence-based framework for culturally appropriate interventions to encourage and equip Mexican-American parents to effectively communicate with their adolescent children about sexuality, and ultimately to address the high rates of teen pregnancy in this U.S.-Mexico border community. ^

A systematic review of literature on socioeconomic disparities in the prevalence of dental caries

Dental caries, also known as tooth decay, are a disease of the oral cavity that affects the tooth structure and leads to the occurrence of cavities in teeth. Dental caries are one of the leading chronic diseases in the population and are very common in childhood. If not treated appropriately, dental caries have debilitating effect on the oral and general health of individuals. ^ Objectives. The aims of this review are to (1) analyze and elucidate the relationship between the social and economic determinants of health like income, education and race/ethnicity and the prevalence of dental caries and (2) identify and understand the pathways/underlying causes through which these factors affect the occurrence of dental caries. This review will provide a foundation for formulation of better oral health policies in future by identifying the key socio-economic factors and pathways affecting the prevalence of dental caries. Knowledge about these socioeconomic factors could be incorporated in the design of future policies and interventions to achieve greater benefits.^ Methods. This review includes information from all pertinent articles, reviews, surveys, reports, peer reviewed literature and web sources that were published after 2000. The selection criterion includes literature focusing on individuals between the ages of 1 to 65 years, and individuals from different subgroups of community based on income, education and race/ethnicity. The analyses of literature include identifying if a relationship between income/education/race and the prevalence of dental caries exists by comparing the prevalence of dental caries in different socio-economic groups. Also included in this review are articles that are relevant to the mechanisms/pathways through which income/education/race affect the prevalence of dental caries.^ Results. Analyses of available literature suggests that disparities in the prevalence of dental caries may be attributed to differences in income, education and race/ethnicity. Higher prevalence of dental caries was observed in African-American and Mexican-American individuals, and in people with low income and low education. The leading pathways through which the socioeconomic factors affect the prevalence of dental caries are the lack of access to dental care, lack of awareness about good oral hygiene beliefs and habits, oral health, inability to afford dental care, lack of social support to maintain oral health and lack of dental insurance.^ Conclusion. Disparities in the prevalence of dental caries exist in various socio-economic groups. The relationship between socio-economic factors and dental caries prevalence should be considered in the development of future policies and interventions that are aimed at reducing the prevalence of dental caries and enhancing oral health status.^

Is family medicine meeting the HIV/AIDS challenge? A national survey of family physicians' beliefs, clinical competence, and experience regarding HIV disease

A national sample of family physicians was surveyed to (1) assess family physicians' beliefs about the human immunodeficiency virus (HIV) and individuals at risk for infection, their clinical competence regarding HIV-related issues, and their experiences with HIV disease; (2) present conclusions to the American Academy of Family Physicians (AAFP) to effect the development of an early clinical care protocol and a continuing medical education curriculum; and (3) collect base-line data for use in the evaluation of an early clinical care protocol and a continuing medical education curriculum, in the case that such programs are developed and disseminated. After considering retired or deceased respondents, of the 2,660 physicians surveyed, 1,678 (63.7%) responded. The resulting sample was representative of the active members of the AAFP. About 77% of the respondents were unable to accurately identify the universal precautions for blood and body fluids to prevent occupational transmission of HIV or hepatitis B virus (HBV). Residency trained and board certified physicians expressed fewer "external constraints," such as fear of losing patients, obviating them from providing treatment to individuals with HIV disease (p =.004 and p $<$.001, respectively). These physicians also manifested fewer "internal constraints" to the provision of HIV treatment, such as fear of becoming infected (p $<$.001 and p =.012, respectively). Residency trained physicians also expressed a greater comfort with discussing sexually-related topics with their patients than did non-residency trained physicians (p $<$.001). There were 67.1% of the physicians surveyed who reported never providing treatment to an individual with HIV disease. Residency trained and board certified physicians expressed a greater likelihood to provide treatment to HIV-infected patients (p $<$.001) than non-residency trained and non-board certified physicians.^ Among the various primary care specialties, family medicine is especially vulnerable to the current challenges of HIV/AIDS. These challenges are augmented by the epidemiologic pattern that characterizes AIDS. For the past several years, we have seen AIDS in this country assume a similar pattern to that seen in most other countries; HIV is becoming increasingly prevalent in the heterosexual population as well as in locations removed from metropolitan centers. This current phase of the epidemic generates greater pressures upon primary care physicians, particularly family physicians, to become better acquainted with the means to provide early care to HIV/AIDS patients and to prevent HIV/AIDS among their patients. Family medicine is especially appropriate for providing care to HIV patients because family medicine involves treatment to all age groups and conditions; other primary care specialties focus on limited patient populations or specific conditions. Family physicians should be armed with the expertise to confront HIV/AIDS. However, family physicians' clinical competence and experience with HIV is not known. The data collected in this survey describes their competencies, attitudes, and experiences. ^

Mexican Americans' awareness, knowledge, and beliefs of hypertension

Cardiovascular disease (CVD) is the number one cause of death for people in Texas as well as Mexico. The progressive morbidity and mortality of CVD can be prevented initially and controlled through regular health screenings or visits to the physician where health markers such as hypertension can be detected and treated. Yet, many people go unaware of existing hypertension not only due to lack of access to health care but to their own personal beliefs, ideas, or perceived barriers that prevent them from seeking preventative health care. ^ The main purpose of this study was to evaluate whether individuals of Mexican origin, who have some form of medical coverage, posses more knowledge, more perceived severity, less perceived barriers, and greater self-efficacy in regards to hypertension than those individuals who have no medical coverage. This was done by addressing the following specific aims: 1.To evaluate the association between individuals who have health care coverage and those who do not have health care coverage in regards to their beliefs of hypertension; 2. To evaluate if there exists a variation among the respondents demographic data and their beliefs of hypertension. ^ The total number of respondents were 150; with 75 being from Cuidad Juarez, and 75 being from El Paso, Texas. The results indicated that the individuals with some form of medical coverage perceived themselves to be more susceptible to suffering a cardiac event or developing heart disease than those who had no form of medical coverage. The individuals with some form of health care coverage also found themselves having less perceived barriers than those who had no health care coverage. The level of education seemed to have some association with individuals perceiving themselves as being susceptible to experiencing a cardiac event if they do not control their hypertension. Regarding self-efficacy, or the self-reported confidence in performing certain behaviors to controlling hypertension, those individuals who perceived themselves as having no self-efficacy had a lower level of education, compared to those who did perceive themselves as possessing self-efficacy. The findings of this study indicate that beliefs regarding hypertension and medical coverage are variables that need to be investigated further for individuals in the El Paso and Cuidad Juarez region. ^

Sociocultural context of knowledge and beliefs about cardiovascular disease among Latino women

We formed an academic-community partnership with the Salsa Caliente program to undertake a project to better understand how Latina women with cardiovascular disease (CVD) or at risk of CVD view and understand CVD. This study's research question examines the sociocultural factors that influence and inform Latino women's perceptions and beliefs about CVD. Seven out the eleven participants in the Salsa Caliente program consented to be interviewed. The data was collected through recorded interviews, which were transcribed and then analyzed for common themes found among all the participants' narratives. The content analysis looking into common themes yielded four: 1) increased awareness of CVD, 2) trust in doctor, 3) delay in doctor visits, and 4) awareness of health. Implications for interventions and further research are discussed.^

Pathway Semantics: An Algebraic Data Driven Algorithm to Generate Hypotheses about Molecular Patterns Underlying Disease Progression

The overarching goal of the Pathway Semantics Algorithm (PSA) is to improve the in silico identification of clinically useful hypotheses about molecular patterns in disease progression. By framing biomedical questions within a variety of matrix representations, PSA has the flexibility to analyze combined quantitative and qualitative data over a wide range of stratifications. The resulting hypothetical answers can then move to in vitro and in vivo verification, research assay optimization, clinical validation, and commercialization. Herein PSA is shown to generate novel hypotheses about the significant biological pathways in two disease domains: shock / trauma and hemophilia A, and validated experimentally in the latter. The PSA matrix algebra approach identified differential molecular patterns in biological networks over time and outcome that would not be easily found through direct assays, literature or database searches. In this dissertation, Chapter 1 provides a broad overview of the background and motivation for the study, followed by Chapter 2 with a literature review of relevant computational methods. Chapters 3 and 4 describe PSA for node and edge analysis respectively, and apply the method to disease progression in shock / trauma. Chapter 5 demonstrates the application of PSA to hemophilia A and the validation with experimental results. The work is summarized in Chapter 6, followed by extensive references and an Appendix with additional material.

Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors

The mechanisms underlying cellular response to proteasome inhibitors have not been clearly elucidated in solid tumor models. Evidence suggests that the ability of a cell to manage the amount of proteotoxic stress following proteasome inhibition dictates survival. In this study using the FDA-approved proteasome inhibitor bortezomib (Velcade®) in solid tumor cells, we demonstrated that perhaps the most critical response to proteasome inhibition is repression of global protein synthesis by phosphorylation of the eukaryotic initiation factor 2-α subunit (eIF2α). In a panel of 10 distinct human pancreatic cancer cells, we showed marked heterogeneity in the ability of cancer cells to induce eIF2α phosphorylation upon stress (eIF2α-P); lack of inducible eIF2α-P led to excessive accumulation of aggregated proteins, reactive oxygen species, and ultimately cell death. In addition, we examined complementary cytoprotective mechanisms involving the activation of the heat shock response (HSR), and found that induction of heat shock protein 70 kDa (Hsp72) protected against proteasome inhibitor-induced cell death in human bladder cancer cells. Finally, investigation of a novel histone deacetylase 6 (HDAC6)-selective inhibitor suggested that the cytoprotective role of the cytoplasmic histone deacetylase 6 (HDAC6) in response to proteasome inhibition may have been previously overestimated.

Chemical composition of Lake George (New York) iron-manganese nodules and underlying sediment

Lake George, New York, is the site of a new discovery of iron-manganese nodules. These nodules occur at a water depth between 21 and 36 m along a stretch of lake extending for about 5 mi north and south of the Narrows, a constricted island-dotted area which separates the north and south Lake George basins. Nodules occur on or within the uppermost 5 cm of a varved glacial clay. Some areas are solidly floored with a carpet of nodules in areas where active currents keep the nodules exposed. The nodules form around nuclei which consist of clay and less commonly of spore capsules, detrital particles, or bark. By their shape we recognize three types of nodules: spherical, discoidal, and lumps. On X-ray examination all nodules show small goethite peaks; in one nodule the manganese mineral birnessite was identified. Manganese and part of the iron appears to be in X-ray amorphous ferromanganese compounds. The Lake George nodules are enriched in iron with respect to marine nodules but are lower in manganese. They have a higher trace element concentration than nodules from other known freshwater lake occurrences, but a lower concentration than marine nodules.

Los profesores de historia y el papel de la lectura en sus clases

La lectura es una herramienta central en la enseñanza y el aprendizaje de la historia. Son conocidos los problemas que afrontan los alumnos para comprender textos históricos, y por eso -entre otras razones- resulta necesario concebir a la lectura como contenido de enseñanza de la Historia. Los aportes de las investigaciones psicolingüísticas permitieron modificar la concepción acerca de la lectura desde dos puntos de vista: se pasó de entenderla como un proceso de descifrado de lo escrito a un proceso de construcción de significado. A la vez, dejó de ser conceptualizada como un conjunto de habilidades para ser interpretada desde una teoría de comprensión global. Actualmente se caracteriza a la lectura como un proceso de construcción de significados y se ha puesto en evidencia que los conocimientos previos del lector sobre la temática del texto constituyen uno de los factores determinantes de la particular interpretación que realiza (Smith, 1983; Goodman, 1982). Construir el significado de un texto de historia supone construir los conceptos, crear y recrear representaciones sobre los hechos, reorganizar el conocimiento anterior incorporando conocimiento nuevo (Aisenberg, 2003). Este trabajo presenta avances de una investigación que busca construir conocimiento sobre las representaciones de los docentes acerca del papel de la lectura en la enseñanza y el aprendizaje de Historia. Las preguntas que orientan esta investigación son: ¿Qué representaciones tienen los profesores de la Escuela Secundaria sobre el papel de la lectura en la enseñanza y el aprendizaje de la historia? Cuando utilizan textos, ¿qué supuestos subyacen a las propuestas didácticas? Se trata de un estudio exploratorio, abordado desde una lógica de investigación cualitativa. En el análisis de las entrevistas realizadas encontramos ideas, percepciones y referencias a prácticas que responderían a concepciones habituales de la enseñanza tradicional de la historia, y otras que estarían influenciadas por los nuevos desarrollos teóricos sobre el tema, difundidos en los últimos años en espacios de formación y en bibliografía sobre las prácticas de lectura en contextos de estudio. Hasta el momento, se han construido dos modos básicos de concebir la relación de la lectura con la historia por parte de los profesores: una relación de interioridad y una de exterioridad. En articulación con cada una, se pueden encontrar diferencias en las concepciones sobre la lectura, en las interpretaciones acerca de las dificultades de lectura y aprendizaje de los alumnos y en las propuestas de enseñanza en las clases de Historia

Los profesores de historia y el papel de la lectura en sus clases

La lectura es una herramienta central en la enseñanza y el aprendizaje de la historia. Son conocidos los problemas que afrontan los alumnos para comprender textos históricos, y por eso -entre otras razones- resulta necesario concebir a la lectura como contenido de enseñanza de la Historia. Los aportes de las investigaciones psicolingüísticas permitieron modificar la concepción acerca de la lectura desde dos puntos de vista: se pasó de entenderla como un proceso de descifrado de lo escrito a un proceso de construcción de significado. A la vez, dejó de ser conceptualizada como un conjunto de habilidades para ser interpretada desde una teoría de comprensión global. Actualmente se caracteriza a la lectura como un proceso de construcción de significados y se ha puesto en evidencia que los conocimientos previos del lector sobre la temática del texto constituyen uno de los factores determinantes de la particular interpretación que realiza (Smith, 1983; Goodman, 1982). Construir el significado de un texto de historia supone construir los conceptos, crear y recrear representaciones sobre los hechos, reorganizar el conocimiento anterior incorporando conocimiento nuevo (Aisenberg, 2003). Este trabajo presenta avances de una investigación que busca construir conocimiento sobre las representaciones de los docentes acerca del papel de la lectura en la enseñanza y el aprendizaje de Historia. Las preguntas que orientan esta investigación son: ¿Qué representaciones tienen los profesores de la Escuela Secundaria sobre el papel de la lectura en la enseñanza y el aprendizaje de la historia? Cuando utilizan textos, ¿qué supuestos subyacen a las propuestas didácticas? Se trata de un estudio exploratorio, abordado desde una lógica de investigación cualitativa. En el análisis de las entrevistas realizadas encontramos ideas, percepciones y referencias a prácticas que responderían a concepciones habituales de la enseñanza tradicional de la historia, y otras que estarían influenciadas por los nuevos desarrollos teóricos sobre el tema, difundidos en los últimos años en espacios de formación y en bibliografía sobre las prácticas de lectura en contextos de estudio. Hasta el momento, se han construido dos modos básicos de concebir la relación de la lectura con la historia por parte de los profesores: una relación de interioridad y una de exterioridad. En articulación con cada una, se pueden encontrar diferencias en las concepciones sobre la lectura, en las interpretaciones acerca de las dificultades de lectura y aprendizaje de los alumnos y en las propuestas de enseñanza en las clases de Historia

Los profesores de historia y el papel de la lectura en sus clases

La lectura es una herramienta central en la enseñanza y el aprendizaje de la historia. Son conocidos los problemas que afrontan los alumnos para comprender textos históricos, y por eso -entre otras razones- resulta necesario concebir a la lectura como contenido de enseñanza de la Historia. Los aportes de las investigaciones psicolingüísticas permitieron modificar la concepción acerca de la lectura desde dos puntos de vista: se pasó de entenderla como un proceso de descifrado de lo escrito a un proceso de construcción de significado. A la vez, dejó de ser conceptualizada como un conjunto de habilidades para ser interpretada desde una teoría de comprensión global. Actualmente se caracteriza a la lectura como un proceso de construcción de significados y se ha puesto en evidencia que los conocimientos previos del lector sobre la temática del texto constituyen uno de los factores determinantes de la particular interpretación que realiza (Smith, 1983; Goodman, 1982). Construir el significado de un texto de historia supone construir los conceptos, crear y recrear representaciones sobre los hechos, reorganizar el conocimiento anterior incorporando conocimiento nuevo (Aisenberg, 2003). Este trabajo presenta avances de una investigación que busca construir conocimiento sobre las representaciones de los docentes acerca del papel de la lectura en la enseñanza y el aprendizaje de Historia. Las preguntas que orientan esta investigación son: ¿Qué representaciones tienen los profesores de la Escuela Secundaria sobre el papel de la lectura en la enseñanza y el aprendizaje de la historia? Cuando utilizan textos, ¿qué supuestos subyacen a las propuestas didácticas? Se trata de un estudio exploratorio, abordado desde una lógica de investigación cualitativa. En el análisis de las entrevistas realizadas encontramos ideas, percepciones y referencias a prácticas que responderían a concepciones habituales de la enseñanza tradicional de la historia, y otras que estarían influenciadas por los nuevos desarrollos teóricos sobre el tema, difundidos en los últimos años en espacios de formación y en bibliografía sobre las prácticas de lectura en contextos de estudio. Hasta el momento, se han construido dos modos básicos de concebir la relación de la lectura con la historia por parte de los profesores: una relación de interioridad y una de exterioridad. En articulación con cada una, se pueden encontrar diferencias en las concepciones sobre la lectura, en las interpretaciones acerca de las dificultades de lectura y aprendizaje de los alumnos y en las propuestas de enseñanza en las clases de Historia