Notes, for the use of the students of the municipal law in the University of Edinburgh: : being a supplement to Sir George Mackenzie's Institutions. /

Verso of t.p. (p. [2] at front) and final page are blank.

The two heiresses of Buccleuch; Ladies Mary and Anna Scott and their husbands, Walter Scott, Earl of Tarras, and James, Duke of Buccleuch and Monmouth, 1647-1732.

"Reprinted from 'The Scotts of Buccleuch'."

The life of the Right Honourable Sir Edward Coke, Knt. : Lord Chief Justice of the King's Bench, etc. /

Includes bibliographical references and index.

Sir Redvers H. Buller, V. C. : the story of his life and campaigns /

"Fifth impression."

Geographical collections relating to Scotland made by Walter Macfarlane,

Vol. 3 edited by Sir Arthur Mitchell and James T. Clark.

Sir David Wilkie, R. A.,

Appendices. --1. Wilkie pictures in public galleries. --II. Wilkie pictures named in this book. --III. Wilkie's etchings.

Holinshed's Chronicles of England, Scotland, and Ireland ...

Includes "The description of Scotland ... by Hector Boetius ... Whereupon is inferred the Historie of Scotland", originally translated for the 1577 edition; also "The Irish history composed and written by Giraldus Cambrensis" translated for the edition of 1587.

The life of Sir Edward Coke, lord chief justice of England in the reign of James I., with memoirs of his contemporaries,

Mode of access: Internet.

The works of Walter Bagehot ...

Same as the Hartford edition of 1889, except that the General index in last volume has been made more complete and the second memoir by Hutton replaced by memoir by R. Giffen.

A systematic arrangement of Lord Coke's first Institute of the laws of England, on the plan of Sir Matthew Hale's analysis; with the annotations of Mr. Hargrave, Lord Chief Justice Hale, and Lord Chancellor Nottingham; and a new series of notes and references to the present time.

Mode of access: Internet.

The Ballantyne-humbug handled : in a letter to Sir Adam Fergusson /

A reply to the "Refutation of the mistatements and calumnies contained in Mr. Lockhart's Life of Sir Walter Scott, bart., respecting the Messrs. Ballantyne. By the trustees and son of the late Mr. James Ballantyne", 1838.

Sir Francis Drake,

Mode of access: Internet.

Musical commonplace book : manuscript, [approximately 1790-approximately 1810]

Contains songs, partly from English operas, and instrumental music.

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

Background: Thyroid receptors, TRa and TR beta, are involved in important physiological functions such as metabolism, cholesterol level and heart activities. Whereas metabolism increase and cholesterol level lowering could be achieved by TR beta isoform activation, TRa activation affects heart rates. Therefore, beta-selective thyromimetics have been developed as promising drug-candidates for treatment of obesity and elevated cholesterol level. GC-1 [ 3,5-dimethyl-4-(4'-hydroxy- 3'-isopropylbenzyl)-phenoxy acetic acid] has ability to lower LDL cholesterol with 600-to 1400-fold more potency and approximately two-to threefold more efficacy than atorvastatin (Lipitor(C)) in studies in rats, mice and monkeys. Results: To investigate GC-1 specificity, we solved crystal structures and performed molecular dynamics simulations of both isoforms complexed with GC-1. Crystal structures reveal that, in TRa Arg228 is observed in multiple conformations, an effect triggered by the differences in the interactions between GC-1 and Ser277 or the corresponding asparagine (Asn331) of TR beta. The corresponding Arg282 of TR beta is observed in only one single stable conformation, interacting effectively with the ligand. Molecular dynamics support this model: our simulations show that the multiple conformations can be observed for the Arg228 in TR alpha, in which the ligand interacts either strongly with the ligand or with the Ser277 residue. In contrast, a single stable Arg282 conformation is observed for TR beta, in which it strongly interacts with both GC-1 and the Asn331. Conclusion: Our analysis suggests that the key factors for GC-1 selectivity are the presence of an oxyacetic acid ester oxygen and the absence of the amino group relative to T(3). These results shed light into the beta-selectivity of GC-1 and may assist the development of new compounds with potential as drug candidates to the treatment of hypercholesterolemia and obesity.

Montagem e colagem na obra de Walter Kempowski

Montage was one of the great innovations of avant-garde literature. As time went by, this technique lost some of its shock effect and became increasingly a method for structuring the text. After the avant-garde literature movement, collage started to be mentioned as a concept together with montage, many times as a complement, but the concepts are often blended into each other. In this article, there will be an attempt to delimit what is montage and what is collage through an exposition of some theories and the examination of the way they are applied in the work of a contemporary writer, the German Walter Kempowski.