Die Juden, und ihre gerechten Ansprüche an die christlichen Staaten : Ein Beitrag zur Milderung der harten Urteile über die jüdische Nation

August Krämer

Vorläufige Bemerkungen über die zweckmäßigsten Mittel zur Beförderung der Kultur und Humanität unter der jüdischen Nation

David ben Mose Fränkel

Über einige bei der jüdischen Nation bestandene, und zum Theile noch bestehende religiöse Sekten

Peter Beer

Über einige bei der jüdischen Nation bestandene, und zum Theile noch bestehende religiöse Sekten

Peter Beer

Delivery of the p67 sporozoite antigen of Theileria parva by using recombinant Salmonella dublin: secretion of the product enhances specific antibody responses in cattle

The p67 sporozoite antigen of Theileria parva has been fused to the C-terminal secretion signal of Escherichia coli hemolysin and expressed in secreted form by attenuated Salmonella dublin aroA strain SL5631. The recombinant p67 antigen was detected in the supernatant of transformed bacterial cultures. Immunization trials in cattle revealed that SL5631 secreting the antigen provoked a 10-fold-higher antibody response to p67 than recombinant SL5631 expressing but not secreting p67. Immunized calves were challenged with a 80% lethal dose of T. parva sporozoites and monitored for the development of infection. Two of three calves immunized intramuscularly with the p67-secreting SL5631 strain were found to be protected, whereas only one of three animals immunized with the nonsecreting p67-expressing SL5631 strain was protected. This is the first demonstration that complete eukaryotic antigens fused to the C-terminal portion of E. coli hemolysin can be exported from attenuated Salmonella strains and that such exported antigens can protect cattle against subsequent parasite challenge.

Immunisation with live attenuated Salmonella dublin expressing a sporozoite protein confers partial protection against Theileria parva

Cattle immunised with a recombinant form of p67, the major surface antigen of Theileria parva sporozoites, have been shown to be protected against parasite challenge. In an attempt to simplify the immunisation procedure live attenuated Salmonella strains expressing p67 have been constructed and used to induce anti-p67 immune responses in cattle. All animals immunised with these strains developed strong antibody responses to p67. Specific T cell responses could be detected in the majority of immunised cattle. Challenge with T. parva sporozoites revealed a significant level of protection in immunised calves compared to naive control animals or animals inoculated with non-recombinant attenuated Salmonella.

Nation und Nationalität

Bruno Lange

Was ist eine Nation?

Ernest Renan

"Gesellschaft und Nation bei den Ostjuden"

Werner Cahnmann

Hermann Heller, Sozialismus und Nation [Rezension]

F.