New Gold(I) complexes: from ligand design to homogeneous catalysis

This PhD thesis summarize the work carried out during three years of PhD course. Several thematic concerning gold(I) chemistry are analysed by crossing data from different chemistry areas as: organic chemistry, organometallic chemistry, inorganic chemistry and computational chemistry. In particular, the thesis focuses its attention on the evaluation of secondary electronic interactions, subsisting between ligand and Au(I) metal centre in the catalyst, and their effects on catalytic activity. The interaction that has been taken in consideration is the Au…Ar π-interaction which is known to prevent the decomposition of catalyst, but exhaustive investigations of further effects has never been done so far. New libraries of carbene (ImPy) and biarylphosphine ligands have been designed and synthetized for the purpose and subsequently utilized for the synthesis of corresponding Au(I) complexes. Resulting catalysts are tested in various catalytic processes involving different intermediates and in combination with solid state information from SC-XRD revealed an unprecedented activation mode which is only explained by considering both electronic nature and strength of Au…Ar π-interaction. DFT calculation carried on catalysis intermediates are in agreement with experimental ones, giving robustness to the theory. Moreover, a new synthetic protocol for the lactonization of N-allenyl indole-2-carboxylic acids is presented. Reaction conditions are optimized with the newly synthetized ImPy-Au(I) catalysts and different substrates are also tested providing a quite broad reaction scope. Chiral ImPy ligands have also been developed for the asymmetric variant of the same reaction and encouraging enantiomeric excess are obtained.

A comprehensive treatise on inorganic and theoretical chemistry.

Contains bibliographies.

Physical chemistry of virus adsorption and degradation on inorganic surfaces: its relation to wastewater treatment /

Mode of access: Internet.

Chemistry : inorganic and organic with experiments /

Includes index.

Chemistry, inorganic and organic, with experiments.

Mode of access: Internet.

Lecture-notes on chemistry for dental students; including dental chemistry of alloys, amalgams, etc., such portions of organic and physiological chemistry as have practical bearing on the subject of dentistry, an inorganic qualitative analysis with specially adapted blowpipe and microscopical tests, and the chemical examination of urine and saliva,

Mode of access: Internet.

Chemistry, inorganic and organic, with experiments /

Mode of access: Internet.

A comprehensive treatise on inorganic and theoretical chemistry,

Supplements accompany some volumes.

A system of chemistry of inorganic bodies.

Mode of access: Internet.

Inorganic colloid chemistry,

I. The collidal elements.--II. The hydrous oxides and hydroxides.--III. The colloidal salts.

Principles of chemistry; an introductory textbook of inorganic, organic, and physiological chemistry for nurses and students of home economics and applied chemistry, with laboratory experiments,

Mode of access: Internet.

Inorganic general, medical and pharmaceutical chemistry, theoretical and practical; a text-book and laboratory manual, containing theoretical, descriptive, and technological chemistry;

Mode of access: Internet.