996 resultados para Fundações (Engenharia) : Patologia


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Pós-graduação em Educação Matemática - IGCE

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Pós-graduação em Ensino de Física - FCT

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Pós-graduação em Engenharia e Ciência de Alimentos - IBILCE

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This work aims to assess a case ofwaterproofing pathology, from the presentation of the pathological manifestations, thecharacterization and quantification of negotiationsproposals. With these data, graphs were elaborated with thepurpose ofemphasizing the cost increase from the time of intervention, to give an increase of 1,429.00 % inthe presented study. Also show the proportion of spending on finishes and waterproofing,demonstratingthe greatinfluence of the finishes in the composition of the treatment costs. Inthisstudy, it was foundthat these finishes made up89% of the total cost. In the bibliographic reference, presented to the active mechanisms, the characterization of waterproofing systems and the most common pathologies. It follows the importance of sealing to ensure integrity of a construction

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This study aims to demonstrate the importance of computer-aided design and drafting (CADD) software for mechanical engineers. In addition, evaluate the software: Inventor 2015, Creo 3.0 and Solid Edge ST8, developed by consolidate companies in the market. In order to accomplish those goals, software application and its advantages will be demonstrated for the industry and for the academia. The evaluation process consists in modeling two mechanical assemblies, in order to compare functional aspects among the software. At the end, it is concluded that the learning of CADD software is of great importance also is the basis for using Computer-aided Engineering (CAE) and Computer-Aided Manufacturing (CAM) tools. Furthermore, it is suggested that Inventor and Solid Edge are more likely to be used in the academia

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This work aims to assess a case ofwaterproofing pathology, from the presentation of the pathological manifestations, thecharacterization and quantification of negotiationsproposals. With these data, graphs were elaborated with thepurpose ofemphasizing the cost increase from the time of intervention, to give an increase of 1,429.00 % inthe presented study. Also show the proportion of spending on finishes and waterproofing,demonstratingthe greatinfluence of the finishes in the composition of the treatment costs. Inthisstudy, it was foundthat these finishes made up89% of the total cost. In the bibliographic reference, presented to the active mechanisms, the characterization of waterproofing systems and the most common pathologies. It follows the importance of sealing to ensure integrity of a construction

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This study aims to demonstrate the importance of computer-aided design and drafting (CADD) software for mechanical engineers. In addition, evaluate the software: Inventor 2015, Creo 3.0 and Solid Edge ST8, developed by consolidate companies in the market. In order to accomplish those goals, software application and its advantages will be demonstrated for the industry and for the academia. The evaluation process consists in modeling two mechanical assemblies, in order to compare functional aspects among the software. At the end, it is concluded that the learning of CADD software is of great importance also is the basis for using Computer-aided Engineering (CAE) and Computer-Aided Manufacturing (CAM) tools. Furthermore, it is suggested that Inventor and Solid Edge are more likely to be used in the academia

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A new multi-energy CT for small animals is being developed at the Physics Department of the University of Bologna, Italy. The system makes use of a set of quasi-monochromatic X-ray beams, with energy tunable in a range from 26 KeV to 72 KeV. These beams are produced by Bragg diffraction on a Highly Oriented Pyrolytic Graphite crystal. With quasi-monochromatic sources it is possible to perform multi-energy investigation in a more effective way, as compared with conventional X-ray tubes. Multi-energy techniques allow extracting physical information from the materials, such as effective atomic number, mass-thickness, density, that can be used to distinguish and quantitatively characterize the irradiated tissues. The aim of the system is the investigation and the development of new pre-clinic methods for the early detection of the tumors in small animals. An innovative technique, the Triple-Energy Radiography with Contrast Medium (TER), has been successfully implemented on our system. TER consist in combining a set of three quasi-monochromatic images of an object, in order to obtain a corresponding set of three single-tissue images, which are the mass-thickness map of three reference materials. TER can be applied to the quantitative mass-thickness-map reconstruction of a contrast medium, because it is able to remove completely the signal due to other tissues (i.e. the structural background noise). The technique is very sensitive to the contrast medium and is insensitive to the superposition of different materials. The method is a good candidate to the early detection of the tumor angiogenesis in mice. In this work we describe the tomographic system, with a particular focus on the quasi-monochromatic source. Moreover the TER method is presented with some preliminary results about small animal imaging.

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Introduzione: Negli ultimi anni, il color-power Doppler si è dimostrato un utile strumento per valutare le alterazioni della vascolarizzazione della parete intestinale nelle patologie del tratto gastro-enterico. Più di recente, i mezzi di contrasto ecografici di II generazione associati all’ecografia real-time con basso indice meccanico (CEUS) hanno permesso di valutare ecograficamente il microcircolo, consentendo la valutazione della vascolarizzazione di parete nelle patologie associate a flogosi e neoangiogenesi. Studi recenti hanno documentato i pattern Doppler e CEUS nella malattia infiammatoria intestinale. Le alterazioni della vascolarizzazione di parete nella patologia neoplastica, invece, sono state finora valutate con sola tecnica Doppler. Recenti studi basati sull’impiego di tale metodica hanno in effetti dimostrato che l’intensità del segnale vascolare di parete correla con la variante istologica della neoplasia e con il suo grado di invasione vascolare costituendo così un parametro di neoangiogenesi tumorale. Pertanto, ottenere mediante CEUS una più accurata definizione del microcircolo di parete potrebbe aiutare nella diagnosi differenziale tra patologia infiammatoria e neoplastica dello stomaco e fornire utili informazioni per valutare l’ aggressività del cancro gastrico.

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The use of scaffolds for Tissue Engineering (TE) is increasing due to their efficacy in helping the body rebuild damaged or diseased tissue. Hydroxyapatite (HA) is the most suitable bioactive ceramic to be used in orthopaedic reconstruction since it replicates the mineral component of the hard tissues, and it has therefore excellent biocompatibility properties. The temporal and spatial control of the tissue regeneration process is the limit to be overcome in order to treat large bone and osteochondral defects. In this thesis we describe the realization of a magnetic scaffolds able to attract and take up growth factors or other bio-agents in vivo via a driving magnetic force. This concept involves the use of magnetic nanoparticles (MNP) functionalized with selected growth factors or stem cells. These functionalized MNP act as shuttles transporting the bio-agents towards and inside the scaffold under the effect of the magnetic field, enhancing the control of tissue regeneration processes. This scaffold can be imagined as a fixed “station” that provides a unique possibility to adjust the scaffold activity to the specific needs of the healing tissue. Synthetic bone graft substitutes, made of collagen or biomineralized collagen (i.e. biomimetic Hydroxyapatite/collagen composites) were used as starting materials for the fabrication of magnetic scaffolds. These materials are routinely used clinically to replace damaged or diseased cartilaginous or bone tissue. Our magnetization technique is based on a dip-coating process consisting in the infilling of biologically inspired porous scaffolds with aqueous biocompatible ferrofluids’ suspensions. In this technique, the specific interconnected porosity of the scaffolds allows the ferrofluids to be drawn inside the structure by capillarity. A subsequent freeze-drying process allows the solvent elimination while keeping very nearly the original shape and porosity of the scaffolds. The remaining magnetic nanoparticles, which are trapped in the structure, lead to the magnetization of the HA/Collagen scaffold. We demonstrate here the possibility to magnetize commercially available scaffolds up to magnetization values that are used in drug delivery processes. The preliminary biocompatibility test showed that the investigated scaffolds provide a suitable micro-environment for cells. The biocompatibility of scaffold facilitates the growth and proliferation of osteogenic cells.