998 resultados para Disponibilidade biológica
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Context - Several paradoxical cases of infliximab-induced or-exacerbated psoriatic lesions have been described in the recent years. There is disagreement regarding the need to discontinue infliximab in order to achieve the resolution of these adverse cutaneous reactions specifically in inflammatory bowel disease (IBD) patients. Objective - To systematically review the literature to collect information on IBD patients that showed this adverse cutaneous reaction, focusing mainly on the therapeutic approach. Methods - A systematic literature review was performed utilizing Medline, Embase, SciELO and Lilacs databases. Published studies were identified, reviewed and the data were extracted. Results - Thirty-four studies (69 IBD patients) met inclusion criteria for review. There was inconsistency in reporting of some clinical and therapeutic aspects. Most patients included had Crohn's disease (89.86%), was female (47.83%), had an average age of 27.11 years, and no reported history of psoriasis (84.05%). The patients developed primarily plaque-type psoriasis (40.58%). There was complete remission of psoriatic lesions in 86.96% of IBD patients, existing differences in the therapeutic approaches; cessation of infliximab therapy led to resolution in 47.83% of cases and 43.48% of patients were able to continue infliximab therapy. Conclusion - As increasing numbers of IBD patients with psoriasis induced or exacerbated by infliximab, physicians should be aware of its clinical manifestations so that appropriate diagnosis and treatment are properly established. The decision whether to continue or discontinue infliximab should be individualized.
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The objective of this study was to evaluate the effect of organic fertilizers (urban solid waste and swine manure) as a source of nutrients and residue from bauxite processing as a corrective of soil acidity, in area cultivated with sugar cane irrigated with potable water and served in the availability of phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg) and sulfur (S) levels in the soil and plants. For this experiment was carried out in pots, using a Alfisol, assessing the availability of the elements in the 0-20 cm layer and the concentration of these nutrients in the leaves of sugarcane. The data showed that the residues increased the concentrations of Ca and Mg in soil, as the concentration of K was not changed and S was not detected, due to the low concentration in the soil. In the leave +1 of sugarcane the residue of bauxite increased levels of N, P, K, Ca and Mg (15.68, 1.73, 10.43, 3.50 and 1.08 g kg-1, respectively). The application of urban solid waste and swine manure also increased the levels of N, K and Ca (11.56, 9.18 and 2.81 g kg-1, respectively). The quality of irrigation water did not alter the availability of P, K, Ca, Mg and S in the soil as well as the levels of these macronutrients in the plant.
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The aim of this work was to evaluate the population density of Pratylenchus brachyurus and Pratylenchus zeae associated with Brachiaria brizantha, B. decumbens and B. humidicola and their influence on forage availability and quality. The experiment was conducte in the Hisaeda Farm, Terenos, MS, Brazil. Soil, roots and plant aerial part were harvest with ten replications each, in one square meter randomized sets encompassing three treatments: Good, Intermediary and Bad, visually characterized, considering the percentage of green material. P. brachyurus and P. zeae density were evaluated in soil and plant roots. Dry matter of green, dead and re-growth materials, plant nutritional status and forage quality were assessed in the aerial plant part. Soil fertility was determined in all harvested samples. Both nematode species were identified from all samples, with a larger numbe in the roots (between 87-311 P. brachyurus and 1-61 P. zeae.10 g-1) than in the soil (0-8 P. brachyurus and 1-39 P. zeae.200 cm-3), however, no significant differences were found in the number of specimens between treatments. Considering that these forage species are perennial and host Pratylenchus spp, there is a tendency to increase the population of these pathogens over time, becoming a serious phytosanitary problem.
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In managing water resources, indexes are used to simplify and quantify available information as well as report the characteristics of a region under study. These indexes may be extremely demanding concerning information required, or very simple, and the water poverty index and Falkenmark index are examples of both extreme situations, respectively. Searching for an index that considers regional and local complexities and information available in developing countries, a new index was developed to evaluate the population accessibility to water resources. This new index combines the Human Development Index and Falkenmark Index and geographic information systems. The results are presented in figures which show the situation at national level, highlighting that the Northeast and Southeast regions are the most vulnerable in Brazil.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Agronomia (Agricultura) - FCA
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
