Estudo e análise do coeficiente de absorção acústico do compósito da fibra de cana

Pós-graduação em Engenharia Mecânica - FEIS

Desenvolvimento, validação e confiabilidade de uma escala de dor aguda pós-operatória em bovinos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Correlação entre condição da superfície do solo agrícola e o coeficiente de absorção acústica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Fator erosividade da chuva de Piraju (SP): distribuição, probabilidade de ocorrência, período de retorno e correlação com o coeficiente de chuva

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Coeficiente de erodibilidade em sulcos e entressulcosde Argissolos coesos estimado pela cor do solo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Proposta metodológica para a correção do coeficiente de retorno de esgoto sanitário em unidades com sistemas de aproveitamento de água pluvial

The use of rainwater for non-potable purposes generates a reduction in the consumption of treated water, however, this reduction is not observed in the generation of wastewater, as this is independent of the water source. In Brazil, the pricing on the services of collection and treatment of sewage, in general, is based on the coefficient of return of the sewage disposal system, which has a relation sewer / water proportional to the consumption of treated water measured at the consumer unit. The use of rainwater originating from utilization systems infer on the coefficient, underestimating the volume of wastewater generated. Therefore, this study presents a methodology for setting the coefficient of return. Different roof areas, reservoir volumes and rates of water consumption situations were simulated. The behavior of adjustment of the coefficient of return were also analyzed for the average area per capita roof (m² / inhabitant) of Rio Claro - SP. As a result, it can be seen that the adjustment of the coefficient of return is directly proportional to the increase of the roof areas and the volumes of reservoirs, and inversely proportional to the total water demand. The corrected coefficient of return showed the minimum value of 0.83 and a maximum value of 1.45, this variation corresponds to the maximum ratio between the demands of total water and rainwater, since the exploitation of rain water should be used only for non-potable uses, according to NBR 15527 / 07. To the municipality of Rio Claro - SP was noted an adjustment of the coefficient of return ranging from 0.99 to 6.61

Determinação de adenosina deaminase, fator de necrose tumoral-alfa e interleucina-1 em gestantes portadoras de pré-eclâmpsia

Preeclampsia is a specific disorder of pregnancy, characterized by arterial hypertension and proteinuria detected after 20 weeks of gestation. This pathology is associated with hyperuricemia, higher levels of pro-inflammatory cytokines, enhanced leukocyte activation and oxidative stress. Adenosine deaminase (ADA) is an enzyme present in all human tissues and, it is involved with the maturation of the immune system. Although its function is not fully understood, ADA is considered an indicator of cellular inflammation and, its increased serum concentration is observed in inflammatory diseases, such as tuberculosis and rheumatoid arthritis. This study aimed to assess serum ADA levels in preeclamptic patients (PE) compared with normotensive pregnant (NT) and non-pregnant women (NP), and to correlate these values with TNF-α and IL-1β production. Ninety pregnant women were included: 60 were pre-eclamptic and 30 were normotensive matched for gestational age. As control group 20 healthy non-pregnant women matched with pregnant for age were included. Peripheral blood mononuclear cells (PMMC) obtained from the three groups studied were cultured with or without lipopolysaccharide (LPS) for 18h at 37oC, and TNF-α and IL-1β production was assessed in the supernatant of cultures by enzyme immunoassay (ELISA). ADA plasmatic concentration was determined by colorimetric method. The results show that ADA plasma levels were significantly higher in PE group compared with NT and NP groups. A positive correlation between ADA and uric acid levels was detected in preeclamptic women. There was no significant difference in relation to ADA levels when PE patients were classified in early and late-onset PE. The endogenous production of IL-1β and TNF-α by PBMC was significantly higher in PE group than in NT and NP women, showing the activation state of these cells in PE. LPS induced...(Complete abstract click electronic access below)

Desenvolvimento de formulações multifuncionais líquido cristalinas contendo nanopartículas de dióxido de titânio e alfa-tocoferol

A destruição da camada de ozônio resulta em um preocupante aumento na incidência de radiação ultravioleta (UV) na superfície da Terra, radiação esta, responsável pela ocorrência de danos na pele e pelo aparecimento do câncer de pele, tipo mais comum de câncer. Assim, neste trabalho foram desenvolvidos sistemas líquido-cristalinos multifuncionais contendo nanopartículas de dióxido de titânio, cuja propriedade fotoprotetora é bem conhecida, e alfa-tocoferol, um composto com ação antioxidante. Com isso, pretendeu-se desenvolver uma formulação que atue como protetor solar inorgânico, bloqueando a radiação UV e impedindo sua penetração que pode causar sérios danos à pele, além de conter o alfa-tocoferol que interage com os radicais livres, diminuindo os danos causados por estes. Para tanto, inicialmente foram preparadas formulações baseadas em dois diagramas de fases, as amostras que apresentaram separação de fase foram excluídas do trabalho, e as outras foram submetidas à análise de microscopia de luz polarizadas. Através da microscopia de luz polarizada foi possível concluir que a estrutura líquido-cristalina é mantida com a incorporação dos ativos no sistema, o que posteriormente foi confirmado com a análise por SAXS. A análise do potencial zeta permitiu verificar que na faixa de pH entre 5 e 7, indicada para produtos de uso tópico, é possível evitar aglomeração das partículas, e com isso obter um visual transparente do produto. A avaliação do comportamento possibilitou concluir que todas as amostras apresentaram uma consistência ideal para aplicação do produto na pele

Impacto da saúde bucal na qualidade de vida de pacientes maiores de 50 anos de duas instituições públicas do município de Araraquara-SP

Introduction: Oral health can affect quality of life, and the OHIP-14 index (Oral Health Impact Profile) is useful for evaluating this impact. Objective: to investigate the impact of oral health conditions on the quality of life of patients over  50  years, assessing, initially, the consistency of the short form of the Oral Health Impact Profile index (OHIP-14). Material and method: A cross-sectional study was performed among 149 patients of two public institutions for routine dental (UNESP) and medical practice (Municipal). They were interviewed using the OHIP-14 formulary, assessing its internal consistency (Cronbach´s alpha coefficient) and the OHIP-mean (additive method). The patients were distributed according to sex, age, and education level. The comparisons of interest were made using Student´s t test at a 5% level of significance. Result: A total of consecutive patients (n = 149) participated of this study (87% response rate). Cronbach´s alpha coefficient was 0.78, denoting a good consistency of the OHIP index. The OHIP mean was 4.98. The most prevalently affected OHIP domains were dimensions of physical pain: painful aching (11.40%) and uncomfortable eating foods (21.50%). There was non-significant difference (p > 0.05) between the mean OHIP value in relation to each of gender, age, and education level. Conclusion: The OHIP-14 is a reliable instrument of assessing oral health-related quality of life, and among patients under routine practice, it was found a low impact of oral conditions on their quality of life in the studied institutions (UNESP and Municipal).

Parâmetros ecocardiográficos e variabilidade da frequência cardíaca em fêmeas caninas com sepse de ocorrência natural devido à piometra e suas correlações com valores séricos de TNF-alfa, IL-1 beta, IL-6, IL-10 e proteína C reativa

Pós-graduação em Medicina Veterinária - FCAV

Terapia gênica com interferon-alfa no controle do câncer colorretal

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Tradução para o português brasileiro, adaptação transcultural e validação do 3D Assessment of Hand Function

Pós-graduação em Bases Gerais da Cirurgia - FMB

Estimativa da correção do coeficiente de retorno de esgoto sanitário em habitações com sistemas de aproveitamento de água pluvial: estudo de caso da cidade de Bauru (SP)

Pós-graduação em Engenharia Civil e Ambiental - FEB

Re-treatment of previous non-responders and relapsers to interferon plus ribavirin with peginterferon alfa-2a (40KD), ribavirin +/- amantadine in patients with chronic hepatitis C: randomized multicentre clinical trial

Introduction. A large number of patients with chronic hepatitis C have not been cured with interferon-based therapy. Therefore, we evaluated the efficacy of amantadine combined with the standard of care (pegylated interferon plus ribavirin) in patients who had not responded to or had relapsed after 24 weeks of treatment with conventional interferon plus ribavirin. Material and methods. Patients stratified by previous response (i.e., non-response or relapse) were randomized to 48 weeks of open-label treatment with peginterferon alfa-2a (401(D) 180 pg/week plus ribavirin 1,000/1,200 mg/day plus amantadine 200 mg/day (triple therapy), or the standard of care (peginterferon alfa-2a [40KD] plus ribavirin). Results. The primary outcome was sustained virological response (SVR), defined as undetectable hepatitis C virus RNA in serum (< 50 IU/mL) at end of follow-up (week 72). Among patients with a previous non-response, 12/53 (22.6%; 95% confidence interval [CI] 12.3-36.2%) randomized to triple therapy achieved an SVR compared with 16/52 (30.8%; 95% CI 18.7-45.1%) randomized to the standard of care. Among patients with a previous relapse 22/39 (56.4%; 95% CI 39.6-72.2%) randomized to triple therapy achieved an SVR compared with 23/38 (60.5%; 95% CI 43.4-76.0%) randomized to the standard of care. Undetectable HCV RNA (< 50 IU/mL) at week 12 had a high positive predictive value for SVR. A substantial proportion of non-responders and relapsers to conventional interferon plus ribavirin achieve an SVR when re-treated with peginterferon alfa-2a (40KD) plus ribavirin. Conclusion. Amantadine does not enhance SVR rates in previously treated patients with chronic hepatitis C and cannot be recommended in this setting.

Coeficiente de cultivo e lâminas de irrigação do maracujazeiro amarelo nas condições semiáridas

The study aimed to determine the coefficient of the yellow passion fruit cultivation and irrigation set capable of increasing crop productivity and quality of production in the environmental conditions of the semi-arid region of Piauí. The experiment was conducted in the Pilot Project for Fruit Crops Irrigated area in Santa Rosa, PI. We used a randomized block design with six treatments and four replications. Treatments (irrigation) were defined according to percentages of reference evapotranspiration (ETo): T1 25%, T2: 50%, T3: 75%, T4: 100%; T5: T6 and 125%: 150%. For monitoring water in the soil profile was used tensiometers. To determine the crop coefficient (Kc) used the water balance in the soil treatment based on 100% replacement of water. Morphological and physiological characteristics of yellow passion fruit were evaluated. The maximum yield of 27.052 kg ha-1 yr-1 was obtained by applying a water depth of 763.80 mm. The values of average fruit weight ranged from 0.207 kg (T6) and 0.159 kg (T1). The average kc obtained for the vegetative stage was 0.57 to 0.94 and flowering stage to fruiting phase 1.04. The water depth of greater efficiency comprise in the range of 75% and 100% ETo.