A importância do conhecimento e da inovação na região metropolitana de Campinas-SP: o caso do condomínio empresarial Praça Capital

The present work is to analyze the importance of exchanging knowledge and technological innovation in Business Condominium Square Capital installed in the Metropolitan Region of Campinas (SP). The condominium corporate Capital Square is the new result of the productive rearrangements that allow the reproduction of capital. This new production space, endowed with infrastructure and sophisticated logistics is able to enable the development of companies installed there in addition to promoting the advancement of technological innovation in the region because of its relations with laboratories, universities and research centers. The research aims to contribute to the understanding of this new form of organization of space activities corresponding to the logic of exchange of knowledge and technological innovation. The logical location of innovation services have similar aspects to economic activities in general, which is distinguished due to the intangible nature of services of high added value through the strategic role of information, the nature of services and because there are services whose logic operation is beyond the economic, but also scientific. The project includes the study in an integrated environment, which allows to evaluate, under various aspects, the importance of established companies and infrastructure available that enable the advancement of skills and knowledge exchange in Capital Square Condo

A organização dos espaços físicos das instituições regulares de ensino e suas contribuições no aprendizado das crianças portadoras de necessidades especiais

O presente trabalho tem como proposta discutir a respeito da organização dos espaços públicos destinados às pessoas portadoras de necessidades especiais. Procura analisar como a questão da acessibilidade vem sendo tratada, nas escolas e no meio urbano, além de identificar, no município de Rio Claro quais as adaptações/adequações foram realizadas recentemente, no sentido de garantir maior acessibilidade aos seus munícipes. O objetivo é o de analisar como se dá a adequação desses espaços e sua contribuição para a vida das pessoas. Constitui-se em pesquisa qualitativa de referencial bibliográfico pautada no levantamento de autores que problematizem a questão do espaço físico, e suas relações com a inclusão, a deficiência e a acessibilidade. Contando ainda com pesquisa de campo e registro fotográfico das adequações no Centro Comercial da cidade de Rio Claro

Estudo da malha urbana e proposta de implantação de um parque tecnológico na cidade de Jacareí

The city of Jacareí above average presents a economic growth of the State of São Paulo, fact that comes if reflecting in the quality of life of the citizens, due to lack of infrastructure to hold the growth rhythm. Today the commercial center of the city, presents diverse urban conflicts with its narrow streets and sidewalk making it difficult to the locomotion and the access the areas and building of public interest gifts in this region. Aiming at the arrival of four multinationals that already make gratings investments in the city and the promise of growth and dinamização of the still bigger economy for the next years, this work studies the urban mesh of the city for a possible implantation of a Technological Park that serves of inductive element of the development of the region north of the city of Jacareí. Place, in which, they are being constructed the multinationals and where, according to Managing Plan of the city, the city hall intends to urbanizar in the next years, with the objective to minimize the areas of urban conflict in the commercial center and of form to absorb the growth of the city. From the study of old experiences, of works carried through on the subject, interviews with city planners of the e region after visits to the place, we will go to argue the possibility of implantation of the Technological Park in Jacareí and optimum place for its installation

Conexão cultura: um projeto de revitalização e reestruturação da estação ferroviária de Guaratinguetá

This work presents an intervention at the Guaratinguetá Railway Station and its surroundings, including this area in the urban context, at this moment isolated of the activities and citizen attentions, offering new activities on this commercial area. The selected area finds itself in a state of neglect and forgetfulness from the urban relations. Located between the periphery of the commercial center and the Paraiba do Sul River, the correlation is tension between the advancement of shops, the railway line, and the natural barrier of the Paraiba River. On the context of these limits, the railroad and the river stand as barriers for the center expansion and the flows that connect the old part of the town with the new part, which is growing and is called “post-city river”. These barriers have relegating properties around them to isolation, despite being located in the center. The area choice and this intervention seeks to break this isolation and the barrier flow, linking areas of opposite sides to form a leak through the barrier of the railway line. The pedestrian flow is prioritized in the project, this flow will be attracted by the program offered and by the new created areas, increasing the space utilization by users and breaking the isolation of urban activities. And entering the area in the context of life of city residents. The attraction of these new flows will be through the implementation of a Cultural Center, supplying a lack of city by spaces that offer this type of activity. Its implementation aims to attract and modify the activities of these spaces and the surrounding areas, one side facing the commercial center, and another facing the river, linking this two sides at the same time that this link provides the expansion of distance traveled and known

Relações de Gênero, memória e identidades no Brasil do século XX

Gender relationships focusing on homages to the women of Assis (a town in the center-western region of the state of São Paulo, Brazil) between 1959 and 1994, are discussed. Homages, expressed in monuments, street names, city squares, schools, libraries, Cultural Centers and other places, are based on the activities of women who benefitted the community. They feature lawyers, politicians, journalists, teachers and common citizens that exceeded their personal limitations and conquered a place acknowledged by society (politically invested) so that their names may be inscribed in the city´s public places. However, acknowledgement of female contributions in the construction of the city is not projected at the same pace or speed as that of males who compose the gallery of ‘remembered men’. This fact brings forth the following questions: If the naming of public places were for decades based on gender, what had changed by the end of the 1950s for such a redefinition? What is the true meaning of such homages? Who are these women and what do they represent?

Plantas medicinais: indicação popular de uso no tratamento de hipertensão arterial sistêmica (HAS)

The aim of this study is to investigate the spontaneous use of medicinal plants by volunteer patients in the treatment of hypertension and to determine the most used plants in this situation. Data were collected through a questionnaire and a semi-structured guided interview applied to patients from a health center in the Midwest region of the state of Sao Paulo, Brazil. Quantitative analysis identified a high number of hypertensive patients spontaneously using herbal treatment. The referred plants were identified by the Herbarium Botu and researched in the literature as to their therapeutic actions. The biggest mistake was observed in the misuse of the Bilberry for the treatment of hypertension, which reveals that health professionals and the community in general should be more careful. As a result we have published an informative booklet, with emphasis on hypertension concepts and on the use of medicinal plants as an alternative therapy method for this disease in order to provide scientific knowledge and scientific research evidence to this practice.

Antennas for the detection of radio emission pulses from cosmic-ray induced air showers at the Pierre Auger Observatory

The Pierre Auger Observatory is exploring the potential of the radio detection technique to study extensive air showers induced by ultra-high energy cosmic rays. The Auger Engineering Radio Array (AERA) addresses both technological and scientific aspects of the radio technique. A first phase of AERA has been operating since September 2010 with detector stations observing radio signals at frequencies between 30 and 80 MHz. In this paper we present comparative studies to identify and optimize the antenna design for the final configuration of AERA consisting of 160 individual radio detector stations. The transient nature of the air shower signal requires a detailed description of the antenna sensor. As the ultra-wideband reception of pulses is not widely discussed in antenna literature, we review the relevant antenna characteristics and enhance theoretical considerations towards the impulse response of antennas including polarization effects and multiple signal reflections. On the basis of the vector effective length we study the transient response characteristics of three candidate antennas in the time domain. Observing the variation of the continuous galactic background intensity we rank the antennas with respect to the noise level added to the galactic signal.

A search for point sources of EeV neutrons

A thorough search of the sky exposed at the Pierre Auger Cosmic Ray Observatory reveals no statistically significant excess of events in any small solid angle that would be indicative of a flux of neutral particles from a discrete source. The search covers from -90 degrees to +15 degrees in declination using four different energy ranges above 1 EeV (10(18) eV). The method used in this search is more sensitive to neutrons than to photons. The upper limit on a neutron flux is derived for a dense grid of directions for each of the four energy ranges. These results constrain scenarios for the production of ultrahigh energy cosmic rays in the Galaxy.

LARGE-SCALE DISTRIBUTION OF ARRIVAL DIRECTIONS OF COSMIC RAYS DETECTED ABOVE 10(18) eV AT THE PIERRE AUGER OBSERVATORY

A thorough search for large-scale anisotropies in the distribution of arrival directions of cosmic rays detected above 10(18) eV at the Pierre Auger Observatory is presented. This search is performed as a function of both declination and right ascension in several energy ranges above 10(18) eV, and reported in terms of dipolar and quadrupolar coefficients. Within the systematic uncertainties, no significant deviation from isotropy is revealed. Assuming that any cosmic-ray anisotropy is dominated by dipole and quadrupole moments in this energy range, upper limits on their amplitudes are derived. These upper limits allow us to test the origin of cosmic rays above 10(18) eV from stationary Galactic sources densely distributed in the Galactic disk and predominantly emitting light particles in all directions.

Measurement of the proton-air cross section at root s=57 TeV with the Pierre Auger Observatory

We report a measurement of the proton-air cross section for particle production at the center-of-mass energy per nucleon of 57 TeV. This is derived from the distribution of the depths of shower maxima observed with the Pierre Auger Observatory: systematic uncertainties are studied in detail. Analyzing the tail of the distribution of the shower maxima, a proton-air cross section of [505 +/- 22(stat)(-36)(+28)(syst)] mb is found.

Estudio de la accidentalidad de ciclistas en los servicios de urgencias extrahospitalaria de Gran Canaria

Programa de doctorado: Avances en traumatología. Medicina del deporte. Cuidado de heridas (interdepartamental). (Bienio 2000/2002). La fecha de publicación es la fecha de lectura

Studio di flussi granulari secchi riprodotti in laboratorio a media scala: Elaborazione di un modello applicabile a casi naturali.

Questa tesi di laurea si riferisce allo studio cinematico e morfologico di flussi granulari composti di materiale vulcanico naturale tramite la strumentazione sperimentale GRANFLOW-sim presso il Dipartimento di Scienze Geologiche dell’Università Autonoma di San Luis Potosì in Messico. E’ stato adottato un approccio sperimentale finalizzato a riprodurre le condizioni fisico-meccaniche di flussi granulari secchi in piccola scala riconducibili a differenti ambienti deposizionali naturali e artificiali. La strumentazione è composta da una canaletta di alimentazione ad inclinazione fissa di 40° ed un piano di deposizione a inclinazioni variabile da 0° a 20° al fine di simulare diverse condizioni deposizionali. Specifici sensori in posizione fissa sullo strumento hanno consentito di raccogliere dati cinematici del flusso e morfologici del deposito corrispondente, rielaborati in profili di velocità e modelli morfologici digitali per ognuno degli esperimenti effettuati. E’ stata osservata una tripartizione del fronte del flusso granulare caratterizzata da i) clasti balistici isolati, ii) un fronte disperso costituito da clasti saltellanti che precede l’arrivo del iii) fronte compatto del flusso costituito dalla parte principale del materiale trasportato. La normalizzazione dei dati cinematici e morfologici ha reso possibile l’elaborazione di relazioni empiriche per lunghezza e larghezza del deposito e velocità massima del flusso in funzione di variabili condizioni di slope-ratio (rapporto tra l’inclinazione del piano di deposizione e della canaletta) e ΔH (differenza di quota tra l’area sorgente del flusso ed il fronte compatto del deposito). Queste relazioni sono state confrontate con i valori ottenuti da Zanchetta et al. (2004) per i flussi granulari naturali nell’area di Sarno, unico caso di studio reale confrontabile con le condizioni sperimentali adottate in questa tesi. Tale confronto ha mostrato una buona corrispondenza tra dati sperimentali e situazione reale nei casi in cui l’effetto di canalizzazione dei flussi granulari era trascurabile. Ciò evidenzia la possibilità di calibrare la strumentazione GRANFLOW-sim al fine di incorporare la valutazione dell’effetto di canalizzazione, ampliando il raggio di utilizzo delle relazioni empiriche ad un numero maggiore di casi di studio di flussi granulari naturali.

The Time-Series Properties on Housing Prices: A Case Study of the Southern California Market

We examine the time-series relationship between housing prices in eight Southern California metropolitan statistical areas (MSAs). First, we perform cointegration tests of the housing price indexes for the MSAs, finding seven cointegrating vectors. Thus, the evidence suggests that one common trend links the housing prices in these eight MSAs, a purchasing power parity finding for the housing prices in Southern California. Second, we perform temporal Granger causality tests revealing intertwined temporal relationships. The Santa Anna MSA leads the pack in temporally causing housing prices in six of the other seven MSAs, excluding only the San Luis Obispo MSA. The Oxnard MSA experienced the largest number of temporal effects from other MSAs, six of the seven, excluding only Los Angeles. The Santa Barbara MSA proved the most isolated in that it temporally caused housing prices in only two other MSAs (Los Angels and Oxnard) and housing prices in the Santa Anna MSA temporally caused prices in Santa Barbara. Third, we calculate out-of-sample forecasts in each MSA, using various vector autoregressive (VAR) and vector error-correction (VEC) models, as well as Bayesian, spatial, and causality versions of these models with various priors. Different specifications provide superior forecasts in the different MSAs. Finally, we consider the ability of theses time-series models to provide accurate out-of-sample predictions of turning points in housing prices that occurred in 2006:Q4. Recursive forecasts, where the sample is updated each quarter, provide reasonably good forecasts of turning points.

Efecto de un nuevo xanthanólido sesquiterpeno sobre la activación de mastocitos inducida por neurópeptidos pro-inflamatorios

Los mastocitos son células del tejido conectivo que participan en la génesis y modulación de las respuestas inflamatorias celulares. En trabajos previos hemos demostrado que xanthatina (xanthanólido sesquiterpeno aislado de Xanthium cavanillesii Schouw) inhibe la activación de mastocitos inducida por secretagogos experimentales. Sin embargo, se desconoce su efecto sobre la activación de mastocitos inducida por estímulos fisiopatológicos. Estos estímulos incluyen, entre otros, los neuropéptidos pro-inflamatorios sustancia P y neurotensina, responsables de una de las principales vías de inflamación neurogénica. El objetivo del presente trabajo fue estudiar el efecto de xanthatina sobre la activación de mastocitos inducida por sustancia P y neurotensina. Mastocitos peritoneales de rata se incubaron con: 1) PBS (basal); 2) sustancia P (100 Fm); 3) neurotensina (50 Fm); 4) xanthatina (8-320 Fm)+sustancia P; 5) xanthatina (8-320 Fm)+neurotensina. La viabilidad de los mastocitos se evaluó con azul tripán. En las soluciones de incubación se cuantificó serotonina liberada (marcador de activación). En las células se cuantificó serotonina remanente (no liberada) y se analizó la morfología celular por microscopía óptica y electrónica de transmisión. Tratamiento estadístico: ANOVA-1 y Tukey-Kramer. La incubación de mastocitos con xanthatina inhibió (P<0,01), en forma dosisdependiente, la liberación de serotonina inducida por sustancia P y neurotensina, sin modificar la viabilidad celular. Los mastocitos tratados con neuropéptidos mostraron características morfológicas de degranulación, mientras que la morfología de los mastocitos tratados con xanthatina+neuropéptido fue semejante a los basales. En conclusión, xanthatina inhibe la activación de mastocitos inducida por sustancia P y por neurotensina. Este sesquiterpeno podría representar una nueva alternativa en el tratamiento de las inflamaciones neurogénicas.

Educación inclusiva y formación docente : nuevas alfabetizaciones

Fil: Giordano, María Francisca. Universidad Nacional de San Luis