Iowa Law Enforcement Academy Annual Report, 2004

Annual Report of the Iowa Law Enforcement Academy for FY 2004

Annual Report, 2002

Annual report produced by the Iowa Department of Public Health

Annual Report, 2000

Annual report produced by the Iowa Department of Public Health

Annual Report, 2001

Annual report produced by the Iowa Department of Public Health

Iowa New Jobs Training Program Annual Report, 2003

Iowa New Jobs Training Program Annual Report produced by Economic Developement

2003 Annual Report of the Iowa Utilities Board

Annual report for the Iowa Utilities Board

Selective neurodegeneration induced in rotation-mediated aggregate cell cultures by a transient switch to stationary culture conditions: a potential model to study ischemia-related pathogenic mechanisms.

Aggregating brain cell cultures at an advanced maturational stage (20-21 days in vitro) were subjected for 1-3 h to anaerobic (hypoxic) and/or stationary (ischemic) conditions. After restoration of the normal culture conditions, cell loss was estimated by measuring the release of lactate dehydrogenase as well as the irreversible decrease of cell type-specific enzyme activities, total protein and DNA content. Ischemia for 2 h induced significant neuronal cell death. Hypoxia combined with ischemia affected both neuronal and glial cells to different degrees (GABAergic neurons>cholinergic neurons>astrocytes). Hypoxic and ischemic conditions greatly stimulated the uptake of 2-deoxy-D-glucose, indicating increased glucose consumption. Furthermore, glucose restriction (5.5 mM instead of 25 mM) dramatically increased the susceptibility of neuronal and glial cells to hypoxic and ischemic conditions. Glucose media concentrations below 2 mM caused selective neuronal cell death in otherwise normal culture conditions. GABAergic neurons showed a particularly high sensitivity to glucose restriction, hypoxia, and ischemia. The pattern of ischemia-induced changes in vitro showed many similarities to in vivo findings, suggesting that aggregating brain cell cultures provide a useful in vitro model to study pathogenic mechanisms related to brain ischemia.

2004 Annual Report of the Superintendent of Banking, 2004

2004 Annual Report of the Superintendent of Banking.

Iowa Department of Public Safety 2004 Annual Report

Annual Report

2004 Annual Report of the Iowa Railway Finance Authority

Annual report for Iowa Railway Finance Authority. Annual Report produced by Iowa Department of Transportation.

Annual Report of Highway Division Highway Research and Development in Iowa, 2004

Annual report for Iowa Department of Transportation

State Library of Iowa Annual Report FY2004

Annual report for State Library of Iowa

Iowa Missing Persons 2003 Annual Report, 2003

Annual report for Missing Persons, Division of Criminal Investigation.

Iowa State Rehabilitation Council 2003-2004 Annual Report

This Council was mandated by the 1992 Amendments to the Rehabilitation Act. Report includes mission, Council duties, accomplishments throughout the year, and member biographies.