162 resultados para palatine tonsil


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Errors in paging, v. 3: 337-344 repeated in numbering.

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King's Vale royall was written by William Smith and William Webb, and was published, together with Samuel Lee's Chronicon cestrense and J. Chaloner's Short treatise of the Isle of Man, by David King. In the present work, Chaloner's Isle of Man has been omitted.

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Extracts of the correspondence. First published by Wolfgang Menzel, in Stuttgart, 1843; Brunet's translation of Menzel's edition first appeared in 1853. It is here completely revised and increased by the addition of fragments published in 1788 by m. de Praun and by other material, part of which was previously unpublished.--cf. Avertissement.

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Twenty-eighth report of the Council of the Chetham society, 1870/71, and list of members, 1871/72, appended to v. 1.

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Register of Bishop Bury: v. 3, p. 208-523.

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"Substantially a reprint of the second edition of 1824."

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The characterization of human dendritic cell (DC) subsets is essential for the design of new vaccines. We report the first detailed functional analysis of the human CD141(+) DC subset. CD141(+) DCs are found in human lymph nodes, bone marrow, tonsil, and blood, and the latter proved to be the best source of highly purified cells for functional analysis. They are characterized by high expression of toll-like receptor 3, production of IL-12p70 and IFN-beta, and superior capacity to induce T helper 1 cell responses, when compared with the more commonly studied CD1c(+) DC subset. Polyinosine-polycytidylic acid (poly I:C)-activated CD141(+) DCs have a superior capacity to cross-present soluble protein antigen (Ag) to CD8(+) cytotoxic T lymphocytes than poly I:C-activated CD1c(+) DCs. Importantly, CD141(+) DCs, but not CD1c(+) DCs, were endowed with the capacity to cross-present viral Ag after their uptake of necrotic virus-infected cells. These findings establish the CD141(+) DC subset as an important functionally distinct human DC subtype with characteristics similar to those of the mouse CD8 alpha(+) DC subset. The data demonstrate a role for CD141(+) DCs in the induction of cytotoxic T lymphocyte responses and suggest that they may be the most relevant targets for vaccination against cancers, viruses, and other pathogens.