Der Wert einer Casa efémera

Der Beitrag erläutert unter dem Blickwinkel der Nützlichkeit ephemerer Bauweisen das Tagungszentrum für die europäische Ratspräsidentschaft Portugals 2007 von Baixa - Atelier de Arquitectura.

Mitochondrial outer membrane proteome of T.brucei reveals novel factors required to maintain mitochondrial morphology

African trypanosomes, the causative agent of Human African Trypanosomiasis (HAT) are among the earliest diverging eukaryotes that have bona fide mitochondria capable of oxidative phosphorylation. The mitochondrial outer membrane (MOM) of T. brucei is essentially unchartered territory. The beta barrel membrane proteins VDAC, Sam50 and archaic TOM are the only MOM proteins that have been characterized so far. Using biochemical fractionation and correlated protein abundance-profiling we were able to raise the protein inventory of the MOM. Of the 82 candidate proteins two-thirds have never been associated with mitochondria before. The function of 42 proteins remains unknown. Known factors involved in the regulation of mitochondrial morphology are virtually absent in T. brucei. Interestingly, RNAi-mediated ablation of three MOM candidate proteins of unknown function resulted in a collapse of the network-like mitochondrion of insect-stage parasites and therefore directly or indirectly are involved in the regulation of mitochondrial morphology in T. brucei.

Restauração agricola da provincia de Goa : memoria apresentada ao 2. Congresso Colonial, realisado em Lisboa em Maio de 1924 ; o estado actual da propriedade

por Santana Rodrigues

Lisbon, Portugal, 1808 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Grundress von Lissabon 1808, E. Müller jun sc. It was published in [1808]. Scale [ca. 1:34,000]. Covers a portion of Lisbon, Portugal. The image inside the map neatline is georeferenced to the surface of the earth and fit to the European Datum 1950, UTM Zone 29N coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, drainage, built-up areas and selected buildings, fortification, and more. Relief is shown by hachures. Includes location map covering Spain and Portugal and inset view: Ansicht von Lissabon. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.