969 resultados para beacon


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This paper proposes a low cost and complexity indoor location and navigation system using visible light communications and a mobile device. LED lamps work as beacons transmitting an identifier code so a mobile device can know its location. Experimental designs for transmitter and receiver interfaces are presented and potential applications are discussed.

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The association of a particular mitochondrial DNA (mtDNA) mutation with different clinical phenotypes is a well-known feature of mitochondrial diseases. A simple genotype–phenotype correlation has not been found between mutation load and disease expression. Tissue and intercellular mosaicism as well as mtDNA copy number are thought to be responsible for the different clinical phenotypes. As disease expression of mitochondrial tRNA mutations is mostly in postmitotic tissues, studies to elucidate disease mechanisms need to be performed on patient material. Heteroplasmy quantitation and copy number estimation using small patient biopsy samples has not been reported before, mainly due to technical restrictions. In order to resolve this problem, we have developed a robust assay that utilizes Molecular Beacons to accurately quantify heteroplasmy levels and determine mtDNA copy number in small samples carrying the A8344G tRNALys mutation. It provides the methodological basis to investigate the role of heteroplasmy and mtDNA copy number in determining the clinical phenotypes.

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Includes index.

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Cover title.

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"Supported in part by contract no. US AEC AT(11-1) 1469."

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Mode of access: Internet.

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v. 1. The pagan civilization.--Jewish heroes and prophets.--v. 3 Ancient achievements.--v. 4. Imperial antiquity.--v. 5. The middle ages.--v. 7. Great women.--v. 8. Great rulers.--v. 9. European statesmen.--v. 10. European leaders.--v. 11. American founders.--v. 12. American leaders.--v. 13. Great writers.--v. 14. The new era.--v. 15. General index.

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Much of Lord's "Modern Europe" reappears in Warriors and statesmen and Modern European Statesmen. cf. Pub. note, v. 8.

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Mode of access: Internet.

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Bound with [2. Thompson, T.] A letter by Thomas Thompson. 1835. -[3] Tuke, S. Letter to John Wilkinson. 2d ed., 1836. -[4] Friends and Independents. 1836. -[5] Eaton, J. Barclay and Penn self-vindicated. 1836. -[6] Gurney, J.J. Strictures on certain parts of an anonymous pamphlet. 1836. -[7. Martin, H.] Philo answered. 1836. -[8. Treffry, J.] Strictures on a late publication. 1836. -[9. Martin, H.] A defence of the original principles. 1836. -[10. Society of Friends - London Yearly Meeting] The committe of the Yearly Meeting, appointed to visit and assist Lancashire Quarterly Meeting. 1835. -[11] Boulton, W. Three essays. 1836. [12. Braithwaite, J. B., comp.] Extracts from the writings of the early Friends. 1836. -[13] Early Friends and Dr. Ash. 1837. -[14] Lean, W. Brief observations. 1838. -[15. Howard, L.] An appeal to the Christian public. 1838. -[16] Bereus, pseud. A defence of the Friends' doctrine of baptism. 1838. -[17] Richardson, W. A scriptural examination. 1839,

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Imprint from NUC pre-56.