955 resultados para Woodruff, Jane C.


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National Highway Traffic Safety Administration, Washington, D.C.

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National Highway Traffic Safety Administration, Washington, D.C.

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National Highway Traffic Safety Administration, Washington, D.C.

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National Highway Traffic Safety Administration, Washington, D.C.

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Mode of access: Internet.

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"May, 1981."

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Top Row: Lisa Abe, Benita C. Aldrich, Elizabeth A. Alexander, Christina Andrakovich, Andrea A Astalos, Aimee K. Baptiste, Jacqueline A. Baransri, Paula A. Bonell, Tonya T. Boven, Sara L. Briggs, Heidi M. Brogger, Maureen A. Burns, Mike R. Byrd

Row 2: Julie A. Camilleri, Maria C. Cano, Sally J. Clement, Martra Finneren, Elizabeth Lobbestael-Monte, Cherryl Drongowski, Laura Stuckey, Elizabeth Scamperle, Amy Wenk, Karin B. Colvin, Gloria R. Crandall, Kristen T. Crane

Row 3: Rita J. Curtis, Cheri K. Davis, Patrick Ahearne, Lynne Yarger, Patricia Tibbits, Kathleen Donahoe, Rosemary Defever, Theresa A. Dietz

Row 4: Maureen Donnelly, Alysse E. Donohue, Susan Holmes, Tina Alexandris, Pam S. Dunbrock, Beth A. Elya

Row 5: Michelle L. Everly, Nazanin Farah, Kathie Fetting, Tanya Meier, Richard A. Fons, Cheryl D. Ford

Row 6: Tonya M. Forton, Alvira Galbraith, Holly B. Goldrick, Sally Sample, Violet Barkauskas, Rhetaugh G. Dumars, Share' Ketefian, Janice B. Lindberg, Elizabeth Pennington, Cheryl A. Grega, Michelle L. grinwis, Paula C. Haffner

Row 7: Peggy A. Harper, Michele R. Haseluhn, Christina M. Hayosh, Michele M. Hopkins, Martha A. James, Elizabeth J. Jameson, Jan I. Joyce, Henry Justusson, Shamrock E. Kealy, Linda A. Kendall, Karrie C. Kerby, Diane M. Kilian, Rene E. Kloosterman, Marie T. Kolar

Row 8: Regina M. Kudla, Julie A. Lasecki, Jenny K. Lindholm, Beth M. Luttrell, Mary E. Malone, Tami J. Nishon, Leah D. Olson, Lori J. Painter, Peggy A. Paulson, Jill A. Rodman, Sherri R. Runciman, Joanne A. Sandler, Patricia L. Sano

Row 9: Leah A. Shults, Catherine E. Slusher, Jennifer A. Snell, Abbe E. Sorin, Iliana I. Staneva, Jennifer R. Stouffer, Jane A. Tanton, Margaret O. Tear, Andrea L. Vandenbergh, Michele M. Vandenburg, Carol A. Waycott, Julie A. Westmeyer, Jane C. Zapytowski, Patricia L. Zickuhr

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Since identification of the CFTR gene over 25 years ago, gene therapy for cystic fibrosis (CF) has been actively developed. More recently gene therapy has been joined by other forms of “genetic medicines” including mRNA delivery, as well as genome editing and mRNA repair-based strategies. Proof-of-concept that gene therapy can stabilize the progression of CF lung disease has recently been established in a Phase IIb trial. An early phase study to assess the safety and explore efficacy of CFTR mRNA repair is ongoing, while mRNA delivery and genome editing-based strategies are currently at the pre-clinical phase of development. This review has been written jointly by some of those involved in the various CF “genetic medicine” fields and will summarize the current state-of-the-art, as well as discuss future developments. Where applicable, it highlights common problems faced by each of the strategies, and also tries to highlight where a specific strategy may have an advantage on the pathway to clinical translation. We hope that this review will contribute to the ongoing discussion about the hype versus reality of genetic medicine-based treatment approaches in CF.

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Land-use change and intensification threaten bee populations worldwide, imperilling pollination services. Global models are needed to better characterise, project, and mitigate bees' responses to these human impacts. The available data are, however, geographically and taxonomically unrepresentative; most data are from North America and Western Europe, overrepresenting bumblebees and raising concerns that model results may not be generalizable to other regions and taxa. To assess whether the geographic and taxonomic biases of data could undermine effectiveness of models for conservation policy, we have collated from the published literature a global dataset of bee diversity at sites facing land-use change and intensification, and assess whether bee responses to these pressures vary across 11 regions (Western, Northern, Eastern and Southern Europe; North, Central and South America; Australia and New Zealand; South East Asia; Middle and Southern Africa) and between bumblebees and other bees. Our analyses highlight strong regionally-based responses of total abundance, species richness and Simpson's diversity to land use, caused by variation in the sensitivity of species and potentially in the nature of threats. These results suggest that global extrapolation of models based on geographically and taxonomically restricted data may underestimate the true uncertainty, increasing the risk of ecological surprises.

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Indenture of deed of land situate between Samuel DeVeaux Woodruff and Jane Woodruff of St. Catharines to Hamilton Killaly Woodruff of St. Catharines regarding Lot no. 22 in the 1st Concession, the south half of Lot no. 20 in Concession B, Broken Lot no. 22 in Concession B, Lots numbered 16, 17, 18, 19 and 20 in Concession C, Lots no. 15, 16, 17, 18, 19 and 20 in Concession D and Lot no. 21 in Concession D in the Township of Mersea (2 copies), Feb. 13, 1891.

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Black and white photograph, 6 ½ cm x 10 cm, of 2 women and a man. The inscription on the back reads “Emma Osgood Mead (“Blind Aunt Emma”), Osgood Woodruff and Henry C. Woodruff (Mrs. Percy Band’s father was a cousin to this ‘Uncle Henry’).

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The marriage certificate of Mr. Hamilton K. Woodruff of St. Catharines and Miss Julia C. Cleveland of Erie, Pennsylvania. This is certificate no. 5221 signed by James C. Wilson. This is accompanied by 2 envelopes; one envelope is from Henry L. Rea, clerk of courts, Erie Pennsylvania to Mr. H. K. Woodruff, the other envelope just says "marriage certificate Mrs. H. K. Woodruff", Nov. 21, 1894.

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Indenture of bargain and sale between Samuel DeVeaux Woodruff and Jane Woodruff of St. Catharines to Patrick Burns of the Township of Grantham regarding part of Lot no. 23 in the 5th Concession in the Township of Grantham - instrument no. 14819. This is listed in Book E, folio 338. October 3, 1864.

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Indenture of bargain and sale between Samuel DeVeaux Woodruff and Jane Woodruff of St. Catharines to Daniel McCarthy of the Township of Grantham regarding 4 1/2 acres of part of Lot no. 23 in the 5th Concession in the Town of Grantham - instrument no. 14821. Listed in Book E, folio 341, October 3, 1864.