898 resultados para Williams, James Hunter, 1926-
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Mode of access: Internet.
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Includes indexes.
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"Niknmoowina," by Jean Ross Hunter: p. 249-274.
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Mode of access: Internet.
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Editors: James Israel, Artur Kollmann, Gustav Kulisch, Paul Wagner.
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Mode of access: Internet.
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Bibliography: p. 17-18.
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Mode of access: Internet.
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Back Row: Jim Hunt, Gerry Williams, James Maddock, Terry Barr, Edward Shannon, Glen Bearss
4th Row: Richard Hill, Louis Baldacci, Michael Rotunno, Jerry Goebel, Gene Snyder, Ron Kramer, Charles Brooks, Thomas Maentz
3rd Row: Thomas Hendricks, James Bates, John Peckham, William Kolesar, John Morrow, James Fox, George Corey, Robert Marion, Tony Branoff
2nd Row: Daniel Cline, Dave Hill, Charles Ritter, Ronald Geyer, John Veselenak, Donald Drake, Stanley Knickerbocker, Edward Hickey
Front Row: Duncan McDonald, Fred Baer, Fritz Crisler, Ted Cachey, Bennie Oosterbaan, Edgar Meads, Arthur Walker
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Front Row: William Billings, Tony Branoff, Richard Beison, Robert Topp, Donald Bennett, Merritt Green, Captain, Charles Ritter, Theodore Kress, Richard Strozewski, Cark Kamhout
Second Row: Ronald Williams, James Balog, Ray VanderZeyde, Robert Hurley, Joseph Shomsky, Robert Milligan, Stanley Knickerbocker, James Bowman, Melvin Bernay, Kenneth Shields, Casimir Chomicz
Third Row: Dean Ludwig, Donald Drake, Norman Canty, Richard Balzhiser, Junior Steilstra, James Dutcher, Robert Dingman, Peri Gagalis, Eugene Knutson, Donald Oldham, Lowell Perry
Fourth Row: Edward Hickey, Duncan MacDonald, Stanley Bowns, Daniel Cline, George Muelich, Herbert Geyer, Russell Swaney, George Dutter, Fred Caffrey, Robert Timm
Fifth Row: John Veselenak, Thad Stanford, Richard O'Shaughnessy, Captain-elect, Donald Evans, Ralph Stribe, Richard Rex, Russell Rescorla, James Wagner, Donald Dugger, Laurence LeClaire
Sixth Row: Donald Zanfagna, Theodore Topor, James Bates, Wayne Melchiori, Robert Matheson, Bruce Bartholomew, Bernhardt Pederson, Roger Zatkoff, Thomas Witherspoon
Back Row: John Treadway, Ted Cachey, Fred Baer, Ray Kenaga, John Rahrig, Arthur Walker, Frank Hall, David Tinkham
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Mode of access: Internet.
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Bibliography: p. 104-106.
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Hemopoietic cells, apparently committed to one lineage, can be reprogrammed to display the phenotype of another lineage. The J2E erythroleukemic cell line has on rare occasions developed the features of monocytic cells. Subtractive hybridization was used in an attempt to identify genes that were up-regulated during this erythroid to myeloid transition. We report here on the isolation of hemopoietic lineage switch 5 (Hls5), a gene expressed by the monocytoid variant cells, but not the parental J2E cells. Hls5 is a novel member of the RBCC (Ring finger, B box, coiled-coil) family of genes, which includes Pml, Herf1, Tif-1alpha, and Rfp. Hls5 was expressed in a wide range of adult tissues; however, at different stages during embryogenesis, Hls5 was detected in the branchial arches, spinal cord, dorsal root ganglia, limb buds, and brain. The protein was present in cytoplasmic granules and punctate nuclear bodies. Isolation of the human cDNA and genomic DNA revealed that the gene was located on chromosome 8p21, a region implicated in numerous leukemias and solid tumors. Enforced expression of Hls5 in HeLa cells inhibited cell growth, clonogenicity, and tumorigenicity. It is conceivable that HLS5 is one of the tumor suppressor genes thought to reside at the 8p21 locus.