Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine

Genomic cancer medicine promises revolutionary change in oncology. The impacts of 'personalized medicine', based upon a molecular classification of cancer and linked to targeted therapies, will extend from individual patient outcomes to the health economy at large. To address the 'whole-of-system' impact of genomic cancer medicine, we have established a prospective cohort of patients with newly diagnosed cancer in the state of Victoria, Australia, about whom we have collected a broad range of clinical, demographic, molecular, and patient-reported data, as well as data on health resource utilization. Our goal is to create a model for investigating public investment in genomic medicine that maximizes the cost:benefit ratio for the Australian community at large.

Healthy together Victoria and childhood obesity-a methodology for measuring changes in childhood obesity in response to a community-based, whole of system cluster randomized control trial

BACKGROUND: Healthy Together Victoria (HTV) - a complex 'whole of system' intervention, including an embedded cluster randomized control trial, to reduce chronic disease by addressing risk factors (physical inactivity, poor diet quality, smoking and harmful alcohol use) among children and adults in selected communities in Victoria, Australia (Healthy Together Communities).

OBJECTIVES: To describe the methodology for: 1) assessing changes in the prevalence of measured childhood obesity and associated risks between primary and secondary school students in HTV communities, compared with comparison communities; and 2) assessing community-level system changes that influence childhood obesity in HTC and comparison communities.

METHODS: Twenty-four geographically bounded areas were randomized to either prevention or comparison (2012). A repeat cross-sectional study utilising opt-out consent will collect objectively measured height, weight, waist and self-reported behavioral data among primary [Grade 4 (aged 9-10y) and Grade 6 (aged 11-12y)] and secondary [Grade 8 (aged 13-14y) and Grade 10 (aged 15-16y)] school students (2014 to 2018). Relationships between measured childhood obesity and system causes, as defined in the Foresight obesity systems map, will be assessed using a range of routine and customised data.

CONCLUSION: This research methodology describes the beginnings of a state-wide childhood obesity monitoring system that can evolve to regularly inform progress on reducing obesity, and situate these changes in the context of broader community-level system change.

Documento conjunto de las comisiones regionales para la Primera Reunión del Comité Preparatorio de la Conferencia Mundial en la Cumbre sobre Desarrollo Social = Joint paper of the regional commissions for the First Meeting of the Preparatory Committee of the Whole of the World Summit for Social Development

Incluye Bibliografía

Whole of Government Approach for Institutional and Policy Coherence

The comprehensive structure of cooperation at domestic level reflects on bilateral, regional and global level.

Foiled; or, A struggle for life and liberty. A drama, in four acts ... To which is added a description of the costumes, cast of the characters ... and the whole of the stage business.

Mode of access: Internet.

A judge by proxy, farce in one act ... To which is added description of the costumes, cast of the characters ... and the whole of the stage business ...

Mode of access: Internet.

History of Seneca County : containing a detailed narrative of the principal events that have occurred since its first settlement down to the present time ; a history of the Indians that formerly resided within its limits ; geographical descriptions, early customs, biographical sketches, &c., &c., with an introd., containing a brief history of the state, from the discovery of the Mississippi River down to the year 1817, to the whole of which is added an appendix, containing tabular views, &c. /

"Constitution of Ohio ... A.D. 1802": p. [191]-213.

A colonel's mishap, a farce comedy, in one act ... To which is added a description of the costumes, cast of the characters ... and the whole of the stage business.

Mode of access: Internet.

Cousin Josiah, a musical sketch in one scene ... To which is added a description of the costumes, cast of the characters ... and the whole of the stage business ...

Without music.

A guide to collectors. 3,500 illustrations. English furniture, decoration, woodwork & allied arts during the last half of the seventeenth century, the whole of the eighteenth century, and the earlier part of the nineteenth,

Mode of access: Internet.

The lady of Lyons; or, Love and pride. A play in five acts from the author's latest edition. To which are added descriptions of the costumes ... and the whole of the stage business.

Mode of access: Internet.

Mickey Free, a sketch in one scene ... Together with a description of the costumes, cast of the characters ... and the whole of the stage business.

Mode of access: Internet.