Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico.

Up to 60% of U.S. visitors to Mexico develop traveler's diarrhea (TD), mostly due to enterotoxigenic Escherichia coli (ETEC) strains that produce heat-labile (LT) and/or heat-stable (ST) enterotoxins. Distinct single-nucleotide polymorphisms (SNPs) within the interleukin-10 (IL-10) promoter have been associated with high, intermediate, or low production of IL-10. We conducted a prospective study to investigate the association of SNPs in the IL-10 promoter and the occurrence of TD in ETEC LT-exposed travelers. Sera from U.S. travelers to Mexico collected on arrival and departure were studied for ETEC LT seroconversion by using cholera toxin as the antigen. Pyrosequencing was performed to genotype IL-10 SNPs. Stools from subjects who developed diarrhea were also studied for other enteropathogens. One hundred twenty-one of 569 (21.3%) travelers seroconverted to ETEC LT, and among them 75 (62%) developed diarrhea. Symptomatic seroconversion was more commonly seen in subjects who carried a genotype producing high levels of IL-10; it was seen in 83% of subjects with the GG genotype versus 54% of subjects with the AA genotype at IL-10 gene position -1082 (P, 0.02), in 71% of those with the CC genotype versus 33% of those with the TT genotype at position -819 (P, 0.005), and in 71% of those with the CC genotype versus 38% of those with the AA genotype at position -592 (P, 0.02). Travelers with the GCC haplotype were more likely to have symptomatic seroconversion than those with the ATA haplotype (71% versus 38%; P, 0.002). Travelers genetically predisposed to produce high levels of IL-10 were more likely to experience symptomatic ETEC TD.

Parental Employment and Home Visiting Program Service Delivery

Home visiting programs, which provide in-home services to disadvantaged families with young children, rest on the assumption that poor parents can be reached at home. Increased levels of maternal employment raise questions about this assumption. In this study, longitudinal data collected for a home visiting program evaluation were analyzed to assess whether employment patterns of parents who receive home visiting services reflect employment patterns of other poor mothers between 1995 and 2000. The study also addresses the relationship between maternal employment and home visiting service intensity. To effectively reach home visiting participants, service providers may need to modify service delivery practices.

Martine's hand-book of etiquette and guide to true politeness : a complete manual for those who desire to understand the rules of good breeding, the customs of good society, and to avoid incorrect and vulgar habits : containing clear and comprehensive directions for correct manners, dress, and conversation, instructions for good behavior at dinner parties and the table : together with the etiquette of the ball and assembly room, evening parties, deportment in the street and when traveling, and the usage to be observed when visiting or receiving calls : to which is added the etiquette of courtship, marriage, domestic duties, and fifty-six rules to be observed in general society /

"Almost every gentleman has wine at his table whenever he has invited guests"-- p. [74].

The new American cook book : containing thousands of recipes, practical suggestions and methods for the household contributed by celebrated chefs and more than two hundred experienced housekeepers, who are recognized authorities in the culinary art, and covering every branch of cookery : with special directions for serving at table, also preserving, pickling, candy-making, etc. : presenting the most healthful, palatable, economical and approved use of the foods of the twentieth century.

Includes indexes.

The visiting teacher in the United States.

Mode of access: Internet.

Parodies for housekeepers,/

Mode of access: Internet.

A State program for visiting teachers : a statement of policies and interpretation of Act 38 of the Public Acts of 1944, Extra Session.

"A plan for helping with problems of community, home, school, law, health, church, family, welfare, recre..."-- Cover

Evidence taken and received by the Commissioners appointed by His Majesty George IV., July 23d, 1826; and reappointed by His Majesty William IV., October 12th, 1830; for visiting the universities of Scotland; presented to both Houses of Parliament by command of His Majesty.

v. 1. University of Edninburgh. -- v. 2. University of Glasgow. -- v. 3. University of St. Andrews. -- v. 4. University of Aberdeen.

Notes on Cuba : containing an account of its discovery and early history ; a description of the face of the country, its population, resources, and wealth ; its institutions, and the manners and customs of its inhabitants ; with directions to travellers visiting the island /

Mode of access: Internet.

Getting the most from a site visit : a guide to assist schools visiting a Leadership and Learning Site for Reading Best Practices /

Includes a list of the Reading Best Practice Sites in Illinois and a list of the possible teaching strategies that are appropriate with each of the fourteen Best Practices.