William Blair Townsend letter and receipt books, 1743-1805, bulk 1744-1777

The collection consists of two volumes, which date from 1743 to 1805, spanning his whole career as a merchant. Volume one is a letter book containing Townsend's business correspondence from November 23, 1743 to December 12, 1774. Most of the letters were written to American (many in North Carolina) and British (predominately in London) merchants. His earliest letters document his efforts to establish himself as a trader. Over time his letters turn to illustrate the common problems faced by many merchants: damaged goods, overpriced goods, embargos, and high freight costs. Particularly enlightening are his comments on the challenges of doing business throughout the French and Indian War and the years leading up to the American Revolution. He most frequently corresponded with London merchants Champion & Hayley, Lane & Booth, Lane Son & Fraser, Harrison & Ansley, and Leeds merchant Samuel Elam. In addition he frequently corresponded with Eliakim Palmer, colonial agent and merchant in London, as well as Dr. Walley Chauncy of North Carolina. He dealt in a wide variety of goods including molasses, rum, tar, medicines, pitch, saddles, tallow, hides, skins, pickled beef and pork, and wine. The letters also document Townsend's involvement in the slave trade through his occasional purchases of slaves.

History of the expedition under the command of Captains Lewis and Clarke, to the sources of the Missouri ... : performed during the years 1804, 1805, 1806, by order of the government of the United States /

The chapter on natural history (1st edition, v. 2, chapter 7) is in this edition transferred to the appendix. In this appendix the Estimate of the western Indians is given under the heading: "Enumeration of Indian nations and their places of general residence."

Novisima recopilación de las Leyes de España : dividida en XII libros : en que se reforma la Recopilación publicada por el Señor Don Felipe II en el año de 1567, reimpresa últimamente en el de 1775, y se incorporan las pragmáticas, cédulas, decretos, órdenes y resoluciones Reales, y otras providencias no recopiladas, y expedidas hasta el de 1804 /

Indices.

Novísima recopilacion de las leyes de España : Dividida en XII. libros, en que se reforma la Recopilacion publicada por el Señor Don Felipe II. en el año de 1567, reimpresa últimamente en el de 1775: y se incorporan las pragmáticas, cédulas, decretos, órdenes y resoluciones reales, y otras providencias no recopiladas, y expedidas hasta el de 1804.

The "Suplemento" (86 p.) has special t.-p. and separate paging.

History of the expedition under the command of Captains Lewis and Clarke : to the sources of the Missouri, thence across the Rocky Mountains, and down the river Columbia to the Pacific Ocean : performed during the years 1804, 1805, 1806 by order of the government of the United States /

Mode of access: Internet.

Catalogue des monnaies et des médailles antiques du moyen âge et des temps modernes, en or, en argent et en bronze, composant le cabinet numismatique de feu Mr. Gustave Daniel de Lorichs /

Mode of access: Internet.

History of the expedition under the command of Captains Lewis and Clarke, to the sources of the Missouri : thence across the Rockey Mountains, and down the river Columbia to the Pacific Ocean ; performed during the years 1804, 1805, 1806, by order of the government of the United States /

The chapter on natural history (1st edition, v. 2, chapter 7) is in this edition transferred to the appendix. In this appendix the Estimate of the western Indians is given under the heading: "Enumeration of Indian nations and their places of general residence".

Schmidt's Werke, oder, Beschreibendes Verzeichniss sämtlicher Kupferstiche und Radirungen welche der berühmte Künstler George Friedrich Schmidt, Königl Preuss. Hofkupferstecher, Mitglied der Königl. Academien zu Berlin, Paris, und der Kaiserlichen zu St. Petersburg von anno 1729 bis zu seinem Tode 1775 verfertigt hat /

Frontispiece portrait of Georg Friedrich Schmidt engraved by D. Berger after a design by Schmidt himself.

Novanglus, and Massachusettensis; or, Political essays, published in the years 1774 and 1775, on the principal points of controversy, between Great Britain and her colonies.

Massachusettensis (p. [141]-227) consists of a series of 17 letters dated December 12, 1774-April 3, 1775, which first appeared in the "Massachusetts gazette and post boy."

Statutes enacted by the royal legislature of Georgia from its first session in 1754 to 1768 [and Statutes, colonial and revolutionary, 1768 to 1773, and 1774 to 1805].

Many of the acts, 1782-1805 (vol. XIX, pt. II, p. 174-577) are given by title only and are mostly amendments to earlier colonial or revolutionary acts.

History of the expedition under the command of Captains Lewis and Clarke [sic], to the sources of the Missouri, thence across the Rocky Mountains, and down the River Columbia to the Pacific Ocean : performed during the years 1804, 1805, 1806, by order of the government of the United States /

Advertisements on p. [1]-8 at end of v. 2.

The invasion of Canada in 1775: including the Journal of Captain Simeon Thayer, describing the perils and sufferings of the army under Colonel Benedict Arnold, in its march through the wilderness to Quebec:

The notes include muster rolls, biographical sketches, etc.

A fragment of the LG3 peptide of endorepellin is present in the urine of physically active mining workers : a potential marker of physical activity

Biomarker analysis has been implemented in sports research in an attempt to monitor the effects of exertion and fatigue in athletes. This study proposed that while such biomarkers may be useful for monitoring injury risk in workers, proteomic approaches might also be utilised to identify novel exertion or injury markers. We found that urinary urea and cortisol levels were significantly elevated in mining workers following a 12 hour overnight shift. These levels failed to return to baseline over 24h in the more active maintenance crew compared to truck drivers (operators) suggesting a lack of recovery between shifts. Use of a SELDI-TOF MS approach to detect novel exertion or injury markers revealed a spectral feature which was associated with workers in both work categories who were engaged in higher levels of physical activity. This feature was identified as the LG3 peptide, a C-terminal fragment of the anti-angiogenic / anti-tumourigenic protein endorepellin. This finding suggests that urinary LG3 peptide may be a biomarker of physical activity. It is also possible that the activity mediated release of LG3 / endorepellin into the circulation may represent a biological mechanism for the known inverse association between physical activity and cancer risk / survival.