University High School

Southeast view of building at corners of Monroe and East University. Building first housed University High School in 1924; University Elementary School added in 1930; later became UM School of Education. Perkins, Fellows & Hamilton, architects for University High School; Malcolmson & Higginbotham, architects for Elementary School (sw wing).

Law School

Jordan & Anderson, architects. Built 1863. Northwest corner of Diagonal on corner of State and North University. Served as Law School for sixty years. An 1898 addition completely altered the exterior, removed the tower, and added a new south wing (Spier & Rohns, architect). Regents met in south wing until 1933. When Law moved to Hutchins Hall in 1933, building was renamed Haven Hall in honor of Erastus O. Haven, president, 1863-1869. Haven Hall became an LS&A building until it was destroyed by fire June 6, 1950. Several people in image.

Physics Building

Pond & Pond, architects. Built 1887-1888. Card printed in Germany

Willow Village

Willow Village, was a former war workers' housing unit acquired by UM in 1945. In 1946, the Department of Physical Education for Men inaugurated a temporary intramural program for students in residence there. University of Michigan News Service stamp on verso. Person in doorway.

Newberry Residence

Kahn & Wilby, architects. Built in 1915. G.E. Christman Co., contractor. First dormitory for women opened for summer session 1915. Gift of Truman H. and John S. Newberry and Mrs. Henry Newberry Joy. Label on verso: Graphic Arts Corporation of Ohio. Design. Fine Printing Papers. Illustration. 110 Ottawa Street. Toledo 4, Ohio. Stamp on verso: Return to University of Michigan News Service. Ann Arbor, Michigan.

Administration Building

Harley, Ellington & Day, architects. Occupied in December 1948 by business, administrative, and public service departments, the building was designated as the Administrative Building. Exterior features Marshall Frederick's sculpture. In 1967, upon completion of the Fleming Administration Building, this building became the LS&A Building.

Original General Library

Ware and Van Brunt, architect. An addition was built to the south in 1898. The 1883 portion was torn down in 1918.

The Wheel and cycling trade review.

Latest issue consulted: Vol. 22-no. 24, number 570 (Jan. 26, 1899); title from cover.

Modelo de negocio para Urbana Bikes

El presente documento es el trabajo de grado) realizado por los autores con el fin de optar al título de magíster en Administración (MBA) de la Universidad EAFIT -- Está fundamentado en un estudio comparativo entre los diferentes conceptos de negocio, metodologías de modelos de negocios, planes de negocios y los diversos métodos de abastecimiento -- Arrojó como resultado que la técnica más adecuada para ser aplicada a las características propias de un prototipo de negocio basado en la oportunidad de mercado identificada en el área metropolitana del valle de Aburrá, como son las bicicletas de los tipos fixies, urbanas y eléctricas, es la ontología de modelo de negocios propuesta por Alexander Osterwalder -- Gracias a esta técnica se identificaron, desde el punto de vista estratégico, los elementos de generación de valor del negocio a partir del análisis de la propuesta de valor, los canales de distribución, las relaciones con los futuros clientes, las asociaciones clave, la segmentación del mercado y la estructura de costos, entre otros; además, se establece la forma óptima de abastecimiento de bicicletas para su comercialización -- Cabe resaltar que dichas bicicletas poseen elementos diferenciadores de estilo, confort y practicidad sobre las demás comercializadas en la ciudad y se han convertido en la última tendencia de dicho tipo de vehículos en las principales ciudades del mundo y han llegado a crear un estilo identificado de ciclistas urbanos -- Lo anterior se alinea con un plan estratégico del Área Metropolitana del Valle de Aburrá que busca incentivar el uso de la bicicleta como medio de transporte alternativo

Synthetic studies towards the total synthesis of hexacyclinic acid

In the first chapter of this thesis, published works found in the literature about hexacyclinic acid and FR182877 are reported and commented. A quick summary of the previous work done in the Prunet group is also described. In the second and third chapter, a more detailed account of the work undertaken during this PhD was given. Firstly, syntheses of two ABC tricycles incorporating tert-butyl and (trimethylsilyl)ethyl esters were undertaken. These syntheses include two key steps previously developed in the group, a diastereoselective Michael addition and a Snider cyclisation. Multiple conditions for the hydrolysis of the esters were attempted but none of them gave the desired product. The main part of this work is focused on the synthesis of a CDEF model and in particular about the development of the key step, the formation of a nine-membered ring. Several DEF fragments were synthesised in short synthetic sequences and as single isomers. Six different synthetic pathways were developed in total and a novel method, a Michael/elimination reaction, was found to be a very efficient way to close the desired medium-size ring. From the nine-membered ring, regioselective reduction and palladiumcatalysed allylic substitution led to the formation of the CDF tricycle. Final steps of the synthesis were fruitless and led only to decomposition. A synthesis of a chiral C-ring was also developed during this PhD. II Finally, another project was undertaken, not related to hexacyclinic acid. Methodology developed in the group for the diastereoselective formation of trisubstituted alkenes employing a temporary silicon-tethered ring-closing metathesis was extended to homoallylic alcohols. The first steps of the method were similar to the previous methodology but the end-game had to be modified in favour of an oxidation/reduction sequence to successfully obtain the desired products with the correct geometry. In the fourth chapter, procedures and analytical data for the synthesised compounds previously described are reported.