Solitary fibrous tumor with atypical histological features occurring in the palatine tonsil: an uncommon neoplasm in an uncommon site

Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that usually arises in the pleura. Although this tumor has been described in other sites, including the head and neck area, in the oropharynx it is extremely rare. We report the first case of a SFT arising from the palatine tonsil of a 62-year-old man. The tumor consisted of spindle-shaped cells distributed in a haphazard pattern and presented atypical histological features such as hypercellular areas and high mitotic count. Immunohistochemical studies showed strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin, S-100 protein and cytokeratines were negative. The patient was well without disease 1 year after surgery.

A pro-inflammatory role of lymphoid cells in acute pleurisy in rats

The effect of viable splenic lymphoid cells and their constituents (filtrate) on carrageenan-induced acute pleurisy was investigated in rats. Suspensions of lymphoid cells administered intravenously to recipients just prior to initiation of pleurisy enhance both the volume of exudate and cell accumulation in the pleural cavity 3 h after the irritation. Similar results were observed when filtrate of disrupted lymphoid cells was injected either 30 or 5 min before the carrageenan, but not when administered 30 min afterwards. Suspensions of bone marrow cells, on the contrary, were ineffective in producing an enhancement of the parameters studied. When administered into the pleural cavity together with carrageenan, the lymphoid cell filtrate augmented the inflammatory response to the irritant. Nevertheless, it was ineffective, per se, to elicit any local change. It is suggested that lymphoid cells may play a pro-inflammatory role in the initiation of the process by enhancing both the fluid and the cellular components of inflammation.

Effects of contrast material on computed tomographic measurements of lung volumes in patients with acute lung injury

Background. Intravenous injection of contrast material is routinely performed in order to differentiate nonaerated lung parenchyma from pleural effusion in critically ill patients undergoing thoracic computed tomography (CT). The aim of the present study was to evaluate the effects of contrast material on CT measurement of lung volumes in 14 patients with acute lung injury. Method. A spiral thoracic CT scan, consisting of contiguous axial sections of 10 mm thickness, was performed from the apex to the diaphragm at end-expiration both before and 30 s (group 1; n=7) or 15 min (group 2; n=7) after injection of 80 ml contrast material. Volumes of gas and tissue, and volumic distribution of CT attenuations were measured before and after injection using specially designed software (Lungview®; Institut National des Télécommunications, Evry, France). The maximal artifactual increase in lung tissue resulting from a hypothetical leakage within the lung of the 80 ml contrast material was calculated. Results. Injection of contrast material significantly increased the apparent volume of lung tissue by 83 ± 57 ml in group 1 and 102 ± 80 ml in group 2, whereas the corresponding maximal artifactual increases in lung tissue were 42 ± 52 ml and 31 ± 18 ml. Conclusion. Because systematic injection of contrast material increases the amount of extravascular lung water in patients with acute lung injury, it seems prudent to avoid this procedure in critically ill patients undergoing a thoracic CT scan and to reserve its use for specific indications.

Myxopapillary ependymoma of the posterior mediastinum

A left paravertebral mass discovered incidentally on routine examination in a 39-year-old woman is described. Computerized tomography studies revealed a 7 × 6 cm, well circumscribed, noncalcified soft tissue mass with lobular borders abutting the left inferior pulmonary vein and descending aorta. It was not possible to determine the exact anatomic location of the mass based on the imaging studies as both peripheral lung tumors and posterior mediastinal lesions may exhibit the imaging findings described here. At thoracotomy, the mass was seen to be well circumscribed, focally attached to the pleura but without involvement of lung parenchyma, and situated in the left posterior mediastinum. On histological examination, the lesion showed the classical features of myxopapillary ependymoma. Immunohistochemical studies confirmed this impression by demonstrating strong positivity of the tumor cells for S-100 protein, glial fibrillary acidic protein, and CD99 and negative staining with other differentiation markers. A review of the literature with a discussion of the histologic and radiologic differential diagnosis of these lesions is presented. © 2006 Elsevier Inc. All rights reserved.

Ultrassonografia torácica extracardíaca em pequenos animais

Until recently, ultrasonography was not considered one of the prevailing imaging methods for thoracic evaluation due to its limitations in evaluating lesions located below thoracic gas collections in individuals with normal lung tissue as well as in those with pneumothorax. Nevertheless, ultrasound has an advantage over other imaging techniques. It allows not only differentiating pleural from pulmonary lesions, but also identifying and assessing peripheral pulmonary lesions. Thus, thoracic ultrasound has become more popular in Veterinary Medicine as an ancillary method in the diagnosis and treatment of several diseases of the thoracic cavity, especially in emergency settings. This review aims at providing information on the main alterations found in the chest wall, mediastinum, pleura, lung and diaphragm by means of ultrasonography.

Utilidade da ultra-sonografia no manejo do derrame pleural parapneumônico em crianças

Pós-graduação em Bases Gerais da Cirurgia - FMB

Análise da retirada e substituição do esôfago torácico: estudo experimental em cães

Pós-graduação em Medicina Veterinária - FMVZ

Avaliação da técnica de biopsia pulmonar transtoracica em ovinos clinicamente sadios e os efeitos do procedimento sobre o metabolismo oxidativo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A comunidade zooplanctônica em um canal de maré no estuário do rio Caeté, Bragança (Pará, Brasil)

Poucos são os estudos realizados sobre zooplâncton em estuários na região Bragantina do Estado do Pará. Este trabalho foi realizado em um canal de maré, denominado de Furo do Chato, próximo a localidade de Ajuruteua. Município de Bragança, no litoral do Estado do Pará, e teve por objetivo estudar a composição qualitativa e quantitativa do zooplâncton, bem como as variações sazonais em função das variáveis ambientais, Durante o período de agosto/96 a janeiro/97 foram feitas oito campanhas a cada três semanas, com obtenção de amostras a cada duas horas, durante 24 horas. O Furo do Chato é um canal de maré com forte influência costeira. Assim, a maior parte dos representantes do zooplâncton encontrados são de origem costeira. Além de componentes holoplanctônicos e meroplanctônicos, as amostras de zooplâncton no Furo do Chato apresentaram representantes da fauna bentônica. Dez filos foram identificados: Protozoa, Mollusca, Chordata, Annelida, Cnidaria, Arthropoda, Urochordata, Chaetognatha, Nematoda e Bryozoa. A classe Copepoda teve maior representatividade, tanto pela densidade, pela biomassa como Oela freqüência de ocorrência nas amostras. As categorias mais abundantes e frequentes (>40%) foram Pseudodiaptomus marshi, Acartia iilljeborgi, A. tonsa, Harpacticoida, Sagitta sp., Oiko pleura dioica, Cnidaria, lsopoda, zoeas de caranguejo, pós-larvas de camarão e alevinos de peixes. A abundâncias médias foram baixas (1,07 indiv./m³e 16,43 mg/m³). A comunidade do zooplâncton é mais abundante nos meses de transição do que no período seco A maiores abundâncias ocorreram em geral à noite e durante as marés de sizígia. Contudo, o ciclo diário de marés, a salinidade e as fases lunares não influenciaram a variabilidade do zooplâncton como um todo, mas apenas em algumas categorias isoladamente.

Bioecologia comparada de duas espécies de Cyphomyrmex Mayr (Formicidae: Myrmicinae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fatores determinantes no resultado do tratamento do empiema pleural em crianças: drenagem pleural simples ou videotoracoscopia? Ensaio clínico controlado

Pós-graduação em Bases Gerais da Cirurgia - FMB

Dinâmica populacional do camarão Alpheus brasileiro Anker, 2012 (Decapoda: Caridea: Alpheidae) em Cananéia, extremo sul do estado de São Paulo, Brasil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Hyperacute necrotizing pneumonia and septicaemia caused by to Clostridium perfringens in Cervus timorensis: case report

Clostridia are uncommon causes of pleuropneumonia in wildlife In human and domestic animals,different hemorrhagic pneumonia with involvement of the pleura. In livestock, most cases are associated with sudden changes of diet, iatrogenic lesionscaused by invasive procedures such as thoracente thoracotomy, or traumatic percutaneous introduction of the microorganism.The clinical course of pleuropneumonia by clostridia infections may be very variable, although usually are associated with hyperacute or acute course and high mortality. The pr necrotizing pneumonia and sepsis caused by hyperacute fatal course, highlighting clinical, epidemiological, microbiological, and histopathological aspects.

Ultrassonografia transtorácica extracardíaca: revisão de Literatura

Radiography is usually the primary method of diagnosis to be used in the initial evaluation of the chest. In view of recent technological advances in ultrasound machines, noncardiac transthoracic ultrasound has become an important method of diagnosis for diseases of the lung, pleura, mediastinum and chest wall. Despite limitations due to the difficulty of efficient sound propagation in air, this exam allows fast decisions and makes sample collection safer and more effective. Knowledge of the sonographic chest anatomy is however restricted because of the artifact caused by the presence of air in lungs. When absent, it facilitates the detection of thoracic alterations. The aim of this review is to present the main abnormalities that are likely to be detected by ultrasonography.

Monoclonal antibodies anti-TGF beta 1 and anti-VEGF inhibit the experimental pleurodesis induced by silver nitrate

Background. The mechanisms underlying pleural inflammation and pleurodesis are poorly understood. We hypothesized that the cytokines transforming growth factor beta (TGF beta 1) and vascular endothelial growth factor (VEGF) play a major role in pleurodesis after intrapleural silver nitrate (SN) injection. Method. Forty rabbits received intrapleurally 0.5% SN alone or 0.5% SN + anti-TGF beta 1, anti-IL-8, or anti-VEGF. After 28 days, the animals were euthanized and macroscopic pleural adhesions, microscopic pleural fibrosis, and collagen deposition were analyzed for characterization of the degree of pleurodesis (scores 0-4). Results. Scores of pleural adhesions, pleural fibrosis, total collagen, and thin collagen fibers deposition after 28 days were significantly lower for 0.5% SN + anti-TGF beta 1 and 0.5% SN + anti-VEGF. Significant correlations were found between macroscopic adhesion and microscopic pleural fibrosis with total collagen and thin collagen fibers. Conclusions. We conclude that both TGF beta 1 and VEGF, but not IL-8, mediate the pleural inflammatory response and pleurodesis induced by SN.