Felix Hoppe-Seyler's Handbuch der physiologisch- und pathologisch-chemischen Analyse für Aerzte und Studirende /

Includes bibliographical references and index.

Chimie médicinale : contenant la maniere de préparer les remedes les plus usités, et la méthode de les employer pour la guérison des maladies /

Mode of access: Internet.

Repetitorium der anorganischen chemie mit besonderer rücksicht auf die studiren den der medicin und pharmacie : mit 28 holzstichen.

Mode of access: Internet.

Incompatibilities in prescriptions.

Mode of access: Internet.

Hand book of practical assaying of drugs and galenicals ...

Mode of access: Internet.

D. Christ. Frider. Reuss ... Dispensatorium universale seu lexicon chemico-pharmaceuticum ad tempora nostra accommodatum ; Sectio prior A-L [-Sectio posterior M-Z]

Mode of access: Internet.

Druggists circular.

1907-31 have subtitle: A practical journal of pharmacy and general business organ for druggists.

Grundriss der pharmakochemie,

Mode of access: Internet.

The Druggists' circular and chemical gazette.

Includes Red book price list section (title varies slightly), issued semiannually 1897-1906.

Jahresbericht über die Fortschritte der Pharmakognosie, Pharmacie und Toxikologie.

Vols. for 1866-89 called also 26-49 in continuation of the original numbering of: Canstatt's Jahresbericht über die Fortschritte in der Pharmacie und verwandten Wissenschaften.

Absolute Configuration and Biosynthesis of Pahayokolide A from Lyngbya sp. Strain 15-2 of the Florida Everglades

Pahayokolides A-D are cytotoxic cyclic polypeptides produced by the freshwater cyanobacterium Lyngbya sp. strain 15-2 that possess an unusual β-amino acid, 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid (Athmu). The absolute configuration of pahayokolides A-D was determined using advanced Marfey’s method. It was also confirmed that a pendant N-acetyl-N-methyl leucine moiety in pahayokolide A was absent in pahayokolides B and pahayokolides C-D were conformers of pahayokolide A. Feeding experiments indicated that the biosynthesis of the Athmu sidechain arises from leucine or α-ketoisovalerate, however could not be further extended by three rounds of condensation with malonate units. Putative four peptide and one unique polyketide synthetases in Lyngbya sp. strain 15-2 were identified by using a PCR method and degenerate primers derived from conserved core sequences of known NRPSs and PKSs. Identification of one unique KS domain conflicted with the logic rule that the long side chain of Athmu was assembled by three rounds of ketide extensions if PKSs were involved. A gene cluster (pah) encoding a peptide synthetase putatively producing pahayokolide was cloned, partially sequenced and characterized. Seven modules of the non-ribosomal peptide synthetase (NRPS) were identified. Ten additional opening reading frames (ORFs) were found, responsible for peptide resistance, transport and degradation. Although the predicted substrate specificities of NRPS agreed with the structure of pahayokolide A partially, the disagreement could be explained. However, no PKS gene was found in the pah gene cluster.

Fluorine-18-labeled estrogens, progestins and corticosteroids for receptor-based imaging of breast tumors and target areas of the brain

Estrogens can be labeled with the positron-emitting radionuclide fluorine-18 (t$\sb{1/2}$ = 110 min) by fluoride ion (n-Bu$\sb4$N$\sp{18}$F) displacement of a 16$\beta$-trifluoromethanesulfonate (triflate) derivative of the corresponding estrone 3-triflate, and purification by HPLC. That sequence has been used to synthesize the 11$\beta$-methoxy 1 and 11$\beta$-ethyl 2 analogues of the breast tumor imaging agent, 16$\alpha$-($\sp{18}$F) fluoro-17$\beta$-estradiol (FES). Tissue distribution studies of 1 and 2 in immature female rats show high selectivity for target tissue (T, uterus) vs non-target (NT, muscle and lung), with T/NT ratios being 43 and 17 at one hour after injection for 1 and 2, respectively. The parent estrogen FES has previously been shown to display an intermediate value for tissue selectivity.

The Edinburgh new dispensatory ... : digested in a regular method and the different departments : enriched by the Introduction and application of the later discoveries in Natural History, Chemistry, and Medicines ... new tables of elective atractions ... and copperplates of chemical and pharmaceutical instruments ... / by gentlemen of the Faculty at Edinburgh

Mode of access: Internet.

(An) introduction to pharmaceutical & medical chemistry ...

Mode of access: Internet.