The Formation and Circulation of Early Yanzi Lore, Fourth Century B.C. - Third Century A.D.

Thesis (Ph.D.)--University of Washington, 2016-06

Frederick II et Louis XV, d'apres des documents nouveaux; 1742-1744.

I. La retraite de Prague. Mort de Fleury; Louis XV veut gouverner lui-même. Évacuation de la Bavière; bataille de Dettingue. appendice.--II. Mission de Voltaire à Berlin. Louis XV à l'armée. La maladie du roi. Appendice.

History of the reign of Philip the Second, king of Spain.

Mode of access: Internet.

Cystic Fibrosis from Laboratory to Bedside: The Role of A20 in NF-κB-Mediated Inflammation

Cystic fibrosis (CF) is a lifelong, inflammatory multi-organ disease and the most common lethal, genetic condition in Caucasian populations, with a median survival rate of 41.5 years. Pulmonary disease, characterized by infective exacerbations, bronchiectasis and increasing airway insufficiency is the most serious manifestation of this disease process, currently responsible for over 80% of CF deaths. Chronic dysregulation of the innate immune and host inflammatory response has been proposed as a mechanism central to this genetic condition, primarily driven by the nuclear factor κB (NF-κB) pathway. Chronic activation of this transcription factor complex leads to the production of pro-inflammatory cytokines and mediators such as IL-6, IL-8 and TNF-α. A20 has been described as a central and inducible negative regulator of NF-κB. This intracellular molecule negatively regulates NF-κB-driven pro-inflammatory signalling upon toll-like receptor activation at the level of TRAF6 activation. Silencing of A20 increases cellular levels of p65 and induces a pro-inflammatory state. We have previously shown that A20 expression positively correlates with lung function (FEV1%) in CF. Despite improvement in survival rates in recent years, advancements in available therapies have been incremental. We demonstrate that the experimental use of naturally occurring plant diterpenes such as gibberellin on lipopolysaccharide-stimulated cell lines reduces IL-8 release in an A20-dependent manner. We discuss how the use of a novel bio-informatics gene expression connectivity-mapping technique to identify small molecule compounds that similarly mimic the action of A20 may lead to the development of new therapeutic approaches capable of reducing chronic airway inflammation in CF. 

The King of Saxony's journey through England and Scotland in the year 1844.

Mode of access: Internet.

Original ancedotes of Frederick the Great, king of Prussia, and of his family, his court, his ministers, his academies, and his literary friends.

Mode of access: Internet.

The life and times of Cleopatra, queen of Egypt; a study in the origin of the Roman empire,

pt. I. Cleopatra and Cæsar.--pt. II. Cleopatra and Antony.

The history of the reign of Philip the Second, king of Spain.

Mode of access: Internet.

Original anecdotes of Frederick the Great, King of Prussia, and of his family, his court, his ministers, his academies, and his literary friends; collected during a familiar intercourse of twenty years with that prince.

Mode of access: Internet.

De Aula Attica literarum artiumque fautrice commentationis historicae.

On reel 265 beginning frame no. 94.

Artaxerxes III Ochus and his reign : with special consideration of the Old Testament sources bearing upon the period ... /

"An inaugural dissertation submitted to the Philosophical Faculty of the University of Bern in candidacy for the doctor's degree."

History of Darius the Great /

Added t.-p., with illuminated border.

The religion of ancient Rome;

"Works bearing on the early religion of Rome": p. [114]

History of Darius the Great.

Mode of access: Internet.

History of Cleopatra, queen of Egypt.

Mode of access: Internet.