Memory in children with temporal lobe epilepsy is at least partially explained by executive dysfunction

An association between memory and executive dysfunction (ED) has been demonstrated in patients with mixed neurological disorders. We aimed to investigate the impact of ED in memory tasks of children with temporal lobe epilepsy (TLE). We evaluated 36 children with TLE and 28 controls with tests for memory, learning, attention, mental flexibility, and mental tracking. Data analysis was composed of comparison between patients and controls in memory and executive function; correlation between memory and executive function tests; and comparison between patients with mild and severe ED in memory tests. Children with TLE had worse performance in focused attention, immediate and delayed recall, phonological memory, mental tracking, planning, and abstraction. Planning, abstraction, and mental tracking were correlated with visual and verbal memory. Children with severe ED had worse performance in verbal and visual memory and learning tests. This study showed that ED was related to memory performance in children with TLE. (C) 2012 Elsevier Inc. All rights reserved.

Musicians' working memory for tones, words, and pseudowords

Studies investigating factors that influence tone recognition generally use recognition tests, whereas the majority of the studies on verbal material use self-generated responses in the form of serial recall tests. In the present study we intended to investigate whether tonal and verbal materials share the same cognitive mechanisms, by presenting an experimental instrument that evaluates short-term and working memories for tones, using self-generated sung responses that may be compared to verbal tests. This paradigm was designed according to the same structure of the forward and backward digit span tests, but using digits, pseudowords, and tones as stimuli. The profile of amateur singers and professional singers in these tests was compared in forward and backward digit, pseudoword, tone, and contour spans. In addition, an absolute pitch experimental group was included, in order to observe the possible use of verbal labels in tone memorization tasks. In general, we observed that musical schooling has a slight positive influence on the recall of tones, as opposed to verbal material, which is not influenced by musical schooling. Furthermore, the ability to reproduce melodic contours (up and down patterns) is generally higher than the ability to reproduce exact tone sequences. However, backward spans were lower than forward spans for all stimuli (digits, pseudowords, tones, contour). Curiously, backward spans were disproportionately lower for tones than for verbal material-that is, the requirement to recall sequences in backward rather than forward order seems to differentially affect tonal stimuli. This difference does not vary according to musical expertise.

The growth of glioblastoma orthotopic xenografts in nude mice is directly correlated with impaired object recognition memory

Cognitive dysfunction is found in patients with brain tumors and there is a need to determine whether it can be replicated in an experimental model. In the present study, the object recognition (OR) paradigm was used to investigate cognitive performance in nude mice, which represent one of the most important animal models available to study human tumors in vivo. Mice with orthotopic xenografts of the human U87MG glioblastoma cell line were trained at 9, 14, and 18days (D9, D14, and D18, respectively) after implantation of 5×10(5) cells. At D9, the mice showed normal behavior when tested 90min or 24h after training and compared to control nude mice. Animals at D14 were still able to discriminate between familiar and novel objects, but exhibited a lower performance than animals at D9. Total impairment in the OR memory was observed when animals were evaluated on D18. These alterations were detected earlier than any other clinical symptoms, which were observed only 22-24days after tumor implantation. There was a significant correlation between the discrimination index (d2) and time after tumor implantation as well as between d2 and tumor volume. These data indicate that the OR task is a robust test to identify early behavior alterations caused by glioblastoma in nude mice. In addition, these results suggest that OR task can be a reliable tool to test the efficacy of new therapies against these tumors.

La memoria de Malvinas y la "batalla por la marca" : Bahía Blanca, la guerra de Malvinas, y la refundación nacional (1982-2012)

El presente artículo pretende analizar los significados y representaciones condensados en los emprendimientos para establecer lugares de la memoria de Malvinas en Bahía Blanca desde 1982 hasta el 2012, contextualizándolos en las luchas por la memoria de la guerra a nivel local y nacional. Hace foco en tres iniciativas para construir memoriales de Malvinas en esta ciudad del sudoeste bonaerense -que se imaginó históricamente como la "Capital del sur argentino" y "Puerta de la Patagonia"-, haciendo hincapié en los actores que se involucraron en las "batallas por la marca", sus objetivos y proyectos, así como en las coyunturas de activación memorial.

Frank Willaert, Herman Braet, Thom Mertens y Theo Venckeleer, eds., Medieval Memory. Image and Text , Turnhout: Brepols, Fédération Internationale des Instituts d'Études Médiévales, Textes et Études duMoyen Âge, 27, 2004

Fil: Disalvo, Santiago Aníbal. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

La memoria de Malvinas y la "batalla por la marca" : Bahía Blanca, la guerra de Malvinas, y la refundación nacional (1982-2012)

El presente artículo pretende analizar los significados y representaciones condensados en los emprendimientos para establecer lugares de la memoria de Malvinas en Bahía Blanca desde 1982 hasta el 2012, contextualizándolos en las luchas por la memoria de la guerra a nivel local y nacional. Hace foco en tres iniciativas para construir memoriales de Malvinas en esta ciudad del sudoeste bonaerense -que se imaginó históricamente como la "Capital del sur argentino" y "Puerta de la Patagonia"-, haciendo hincapié en los actores que se involucraron en las "batallas por la marca", sus objetivos y proyectos, así como en las coyunturas de activación memorial.

La memoria de Malvinas y la "batalla por la marca" : Bahía Blanca, la guerra de Malvinas, y la refundación nacional (1982-2012)

El presente artículo pretende analizar los significados y representaciones condensados en los emprendimientos para establecer lugares de la memoria de Malvinas en Bahía Blanca desde 1982 hasta el 2012, contextualizándolos en las luchas por la memoria de la guerra a nivel local y nacional. Hace foco en tres iniciativas para construir memoriales de Malvinas en esta ciudad del sudoeste bonaerense -que se imaginó históricamente como la "Capital del sur argentino" y "Puerta de la Patagonia"-, haciendo hincapié en los actores que se involucraron en las "batallas por la marca", sus objetivos y proyectos, así como en las coyunturas de activación memorial.

Frank Willaert, Herman Braet, Thom Mertens y Theo Venckeleer, eds., Medieval Memory. Image and Text , Turnhout: Brepols, Fédération Internationale des Instituts d'Études Médiévales, Textes et Études duMoyen Âge, 27, 2004

Fil: Disalvo, Santiago Aníbal. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

Frank Willaert, Herman Braet, Thom Mertens y Theo Venckeleer, eds., Medieval Memory. Image and Text , Turnhout: Brepols, Fédération Internationale des Instituts d'Études Médiévales, Textes et Études duMoyen Âge, 27, 2004

Fil: Disalvo, Santiago Aníbal. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

La memoria de Malvinas y la "batalla por la marca" : Bahía Blanca, la guerra de Malvinas, y la refundación nacional (1982-2012)

El presente artículo pretende analizar los significados y representaciones condensados en los emprendimientos para establecer lugares de la memoria de Malvinas en Bahía Blanca desde 1982 hasta el 2012, contextualizándolos en las luchas por la memoria de la guerra a nivel local y nacional. Hace foco en tres iniciativas para construir memoriales de Malvinas en esta ciudad del sudoeste bonaerense -que se imaginó históricamente como la "Capital del sur argentino" y "Puerta de la Patagonia"-, haciendo hincapié en los actores que se involucraron en las "batallas por la marca", sus objetivos y proyectos, así como en las coyunturas de activación memorial.

Obtención de la función receptora en las estaciones sísmicas de banda ancha del Instituto Geográfico Nacional.

La estructura de velocidad en los primeros metros debajo de una estación sísmica produce un cierto efecto sobre el sismograma que ésta registra, dicho efecto se denomina función receptora. Si se conoce esta función, es posible, mediante modelización, obtener esa estructura de velocidad. La onda P que genera un telesismo, queda “atrapada” en los últimos kilómetros de su trayectoria en la estructura próxima a la estación que la registra, reverberando entre las discontinuidades de la misma y convirtiéndose, en algunas partes, en onda S. La diferencia de registro existente entre el sismograma del rayo no atrapado (componente vertical del registro) y el producido por este fenómeno (componente radial), sería la función receptora. En este proyecto, se pretende obtener mediante la técnica de Langston (1979),las funciones receptoras de las 55 estaciones que forman la Red Sísmica de banda ancha del Instituto Geográfico Nacional, con el fin de que en trabajos venideros, sea posible conocer de una manera más realista, la estructura de la corteza terrestre bajo el territorio español. Para la obtención de estas funciones, será necesario trabajar con un conjunto de sismogramas registrados por estaciones de banda ancha a partir de telesismos cuyos parámetros focales reúnan una serie de condiciones, definidas y detalladas ampliamente en esta memoria. Tras un proceso de selección, que será constante a lo largo de todo este trabajo,se van a emplear para el cálculo de las funciones receptoras, un total de 5231 sismogramas, generados por 186 telesismos. Para terminar, a modo de ejemplo y con el objetivo de mostrar la finalidad para la que se ha llevado a cabo este proyecto, se procederá a realizar la inversión de la función receptora obtenida para una de las estaciones sísmicas de la red, obteniendo así, un modelo de velocidades aproximado de la estructura de la litosfera existente bajo dicha estación. Abstract: The speed structure in the first layers under a seismic station produces an effect on the seismogram that is registered. This effect is known as receiver function. It is possible to obtain the speed structure if this function is detected through modelling. The P wave, which generates a teleseism, gets trapped in the final kilometres of its trajectory in the nearby station structure, reverberating among its discontinuities and turning into a S wave. The registered difference between the not caught ray seismogram (vertical component of the register) and the one that is produced by this phenomenon (radial component) would be known as receiver function. This project aims to obtain, through the Langston technique (1979), the receiver function of the 55 stations that make up the Broadband Seismic Network of the National Geography Institute to get to know, in a more realistic way, the structure of the Earth’s crust under the Spanish territory. In order to obtain these functions, it will be necessary to work with a number of seismograms registered by the broadband stations whose focal parameters meet the requirements that are well defined and detailed in the development of this memory. After selecting the appropriate data, that would be constant throughout the development of this project, we are going to apply a total of 5231 seismograms obtained by 186 teleseism to calculate the receivers functions. To conclude, and with the aim of demonstrating the purposes and uses that lie behind the development of this project, we will reverse the receiver function for one of the seismic stations, obtaining a approximate speeds’ model of the lithosphere structure that can be found under the previously mentioned station.

Corrientes en la organización nacional /

Vol. 10 includes discourses and tributes to the memory of Pujol, with biographical data.

Plato on Oblivion. About Memory and Forgetfullness in the Platonic Dialogues

The aim of this paper is to tackle the role of oblivion in the Plato’s dialogues. It takes as work texts the dialogues where the anamnesis doctrine is exposed, and from these writings, but also attending to several other ones, the connexions between oblivion and other Platonic issues, as, e. g., language, memory, experience or love are explored, in order to clarify their relations of mutual dependence. In this way, we attempt to find out in the Platonic oblivion a philosophical sense, which is not disdainful in comparison with the sense and the relevance that the readers of all times have granted to anamnesis; for anamnesis and oblivion are inseparable indeed.

A Mismatch-Based Model for Memory Reconsolidation and Extinction in Attractor Networks

OSAN, R. , TORT, A. B. L. , AMARAL, O. B. . A mismatch-based model for memory reconsolidation and extinction in attractor networks. Plos One, v. 6, p. e23113, 2011.

A Mismatch-Based Model for Memory Reconsolidation and Extinction in Attractor Networks

OSAN, R. , TORT, A. B. L. , AMARAL, O. B. . A mismatch-based model for memory reconsolidation and extinction in attractor networks. Plos One, v. 6, p. e23113, 2011.