A Companhia de Jesus e a formação da cultura sexual brasileira: um estudo histórico e documental a partir dos escritos do padre Manuel da Nóbrega

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O (re) nascer de uma nação: 'portagem' e o destino de um mulato

Pós-graduação em Letras - FCLAS

Rituais de purificação: corporeidades e religões afro-brasileiras

Pós-graduação em Ciências da Motricidade - IBRC

Estudo etnobotânico nas comunidades de Porto Limão, Porto Alambrado e Campo Alegre, na fronteira Brasil-Bolívia, Mato Grosso Brasil

Pós-graduação em Ciências Biológicas (Biologia Vegetal) - IBRC

Perfil mutacional do gene APC em pacientes com polipose adenomatosa familial no estado do Pará

O câncer colorretal é um grave problema de saúde pública na região norte, sendo a 3a neoplasia mais frequente entre os homens e a 2a entre as mulheres. Cerca de 10% destes tumores são hereditários e a polipose adenomatosa familial está entre as principais causas destes. Mutações no gene APC são responsáveis pelo desenvolvimento de tumores nestes pacientes e estão presentes desde a fase mais precoce na carcinogênese, além disso, existe uma relação entre o tipo de mutação e apresentação clínica da doença. Até o presente momento não existe uma publicação com o perfil de mutação do gene APC na região norte do país. Este trabalho tem como objetivo principal, identificar o perfil de mutações no gene APC em famílias do estado do Pará. Um total de 15 pacientes foi analisado provenientes de cinco famílias, todos atendidos no UNACON do HUJBB. Foi realizado a extração de DNA do sangue periférico e realizado um sequenciamento direto em um membro de cada família, obtendo desta forma um screening molecular e os demais membros da família foram genotipados pela técnica ARMS. A análise estatística foi realizada pelos softwares que acompanham o próprio produto. Neste estudo foram encontrados mutações nos 15 membros estudados (provenientes das 5 famílias), 40% das quais eram do tipo frameshift, 35% silenciadoras e 20% nonsense. Sendo que 60% de todas as mutações ocorreram na região MCR. Entre as três mutações mais frequentes na literatura, neste estudo foram encontradas duas: códon 1309 (em 40% dos indivíduos) e no códon 1061 (em 10% dos indivíduos). Estes números foram bem diferentes dos encontrados na literatura, reforçando o papel da miscigenação na frequência das mutações. A mutação c.3956delC foi a única encontrada em todas as famílias analisadas, o que pode comportar-se como um forte biomarcador desta síndrome. A avaliação clínica dos pacientes confirmou a correlação genótipo/fenótipo, sendo um fator determinante para o direcionamento clínico e aconselhamento genético. A plataforma confeccionada para análise de mutações pela técnica ARMS será de grande utilidade, já que conseguiu detectar mutações no 15 indivíduos estudados a um custo bem inferior que o sequenciamento direto por PCR.

Musuko: os filhos da miscigenação

This project is about a book-report, which will discuss the nipo-brazilian’s identity. The Kasato-Maru ship arrived at Santos about a hundred years ago, opening a path that would never be closed: the path between Japan and Brazil, countries both geographically and culturally opposite. Miscegenation brings the nipo-brazilian to life, a individual who does not feel entirely Brazilian or Japanese. The goal of the book is to discuss the nipo-brazilian’s identity, once known that this individual can adopt one or other culture, or even merge both. It is not intended to conclude anything, so the main objective fulfills itself in the research of the possibilities of identities through interviews, theories, Japanese immigration’s history and Brazilian’s culture

Dilemas na tradução de Muse & Drudge (Musa E Mula), de Harryette Mullen: negritude, dissonância e miscigenação

This paper aims to discuss a project of translating part of the work Muse & Drudge, by the award-winning African-American poet Harryette Mullen, into Brazilian Portuguese, with focus on a single poem. In Muse & Drudge Mullen combines cultural critique with humor, lyricism and punning, which has unfolded the frontiers between cultural and racial identity, and has put into question the opposition between popular and high culture. This work analyzes to which extent the proposed translation produces a new set of intertextual relations that might culminate in “unexpected” meanings. It is a goal to understand how the effects of such “unexpected” meanings reveal the “encounter” between the so-called racial “black/white” dichotomy, predominant in the US culture, and the notion of “miscegenation��� and “racial democracy” in Brazil.

Genetic variability of inflammatory genes in the brazilian population

Inflammatory gene variants have been associated with several diseases, including cancer, diabetes, vascular diseases, neurodegenerative diseases, arthritis, and others. Therefore, determining the population genetic composition of inflammation-related genes can be useful for the determination of general risk, prognostic and therapeutic strategies to prevent or cure specific diseases. We have aimed to identify polymorphism genotype frequencies in genes related to the inflammatory response in the Brazilian population, namely, IjBL - 62AT, IjBL - 262CT, tumor necrosis factors alpha (TNFa) - 238GA, TNFa - 308GA, lymphotoxin-alpha (LTa) + 80AC, LTa + 252AG, FAS - 670AG, and FASL - 844TC, considering the white, black, and Pardo ethnicities of the Sa˜o Paulo State. Our results suggest that the Brazilian population is under a miscegenation process at the current time, since some genotypes are not in the Hardy–Weinberg equilibrium. In addition, we conclude that the Pardo ethnicity is derived from a complex mixture of ethnicities, including the native Indian population.

O papel da tradução na construção da identidade da literatura afro-americana no Brasill

This paper discusses the role of translation in the construction of the identity of African-American literature in Brazil, by considering the relations between the Brazilian sociocultural context, infl uenced by biological and cultural miscegenation, and the particular way that the literary criticism represented by essays and translations of the Brazilian critic Sergio Milliet, published in between the 40’s and 60’s, approaches AfricanAmerican poetry, with special focus on Langston Hughes’ poems. In this paper, differences between Brazilian and American racial contexts are brought into light in regard to the discourses on miscegenation and race. It is discussed the extent to which Sergio Milliet developed a racialized identity for African-American poetry in his essays, which, however, was rebuilt through translation, in his anthology Obras Primas da Poesia Universal, with a less racialized perspective so that African-American aesthetics could sound less dissonant and regional and more inclined towards the principle of universality which characterizes the anthology composed of renowned foreign and Brazilian poets.

Mais ou menos negra? Questões de negritude, tradução e a poesia de Harryette Mullen

This paper addresses issues regarding my translation of selected poems by Harryette Mullen, a rising African-American contemporary poet, whose dense poetry works on the black oral tradition, the experimentalism of writing, the (African-American) pop music, in addition to delving into issues such as the representation of (black) female sexuality. One of the complex aspects of her poetry is the notion of miscegenation, conceived as an aesthetic argument and as a constitutive condition of the identity of multiracial Americans. This concept establishes a textuality that questions the accessible intelligibility generally expected from black American poetry, insofar as a mosaic of dissonant voices are brought to light in her text, which makes it difficult to categorize. In Brazil, especially among politically engaged Afro-Brazilians, there has been criticism towards the praise of miscegenation, since the latter has been considered to support of the myth of racial democracy. Building on these aspects, we investigate the extent to which it is a challenge to translate her poetry – based on miscegenation and hybridity as aesthetic constructs – especially when taking into account the discursive locus of readers identified with an Afro-Brazilian aesthetic, particularly critical of miscegenation. From the point of view of translation, we evaluate the extent to which her poetry could be read by the predominant cultural discourse in Brazil, inclined to favor miscegenation as an integral concept of national identity, as a seductively experimental poetry. In view of this, one wonders whether this perspective makes hers poetry “less black” for Afro-Brazilian literary standards.

Entre nativos e exóticos: a mestiçagem na construção de uma nova identidade na caprinovinocultura dos sertões

In the Northeastern Semiarid of Brazil, dynamic among creators of goats and sheep native and exotic bring a range of meanings. In addition to actual trade disputes, conflicts are waged in the realm of ideas, revealing different values and interests around the racial origin of these animals. Between these two segments lies most of the small farmers and the traditional Semiarid sheep and goat raising, based on the use of animals breed, arising from the dynamics of spontaneous crossings, own extensive creations characterized by reduced control over the herds, state which shows a marked contrast to the first two segments. Given that their influence on a traditional creations can result in improved production of small farmers, linked to different social sector research and extension have turned their efforts to construct possible arrangements that are satisfactory to the reversal of historical problems of the region, especially the use of animal miscegenation as a strategy for change. It focuses on the work of these actors, the forms of interaction between them, fulfill the role that ideas, values and attitudes in the face of the possibilities for sheep and goat raising that region.

A influência da raça nas relações de poder: uma análise sobre o município de Araraquara

Analyzing the Brazilian people's formation and its ethnic variety, the racial issue is marked by racism as a tendency of thought that gathers different human races. The miscegenation originated by the crossbreeding occurred widely among Brazil and carried with it a racial prejudice based on European theses about the population's whitening. Since the arrival of the black population to the country, in the condition of slave, their image is stuck to the stigma of inferiority in relation to white people, making it difficult to have a political influence and introduce themselves into the Brazilian dominant elite. We intent to bring the discussion about local power, coronelismo and patronage, trying to demonstrate how the dominant elite's power and resources allocation schemes, put aside the lower-class from the political scene which is even worse for the black population regarding the suffered racial prejudice. Assuming the matters described above, we argue around the insertion of the black people into the political scenario, taking the City of Araraquara -SP as target to analyze the conditions that prevents them from achieving high positions inside the public sector and develop the issue between representation, social inclusion and political participation

Distribution of the CCR5delta32 allele (gene variant CCR5) in Rondonia, Western Amazonian region, Brazil

Since around 1723, on the occasion of its initial colonization by Europeans, Rondonia has received successive waves of immigrants. This has been further swelled by individuals from northeastern Brazil, who began entering at the beginning of the twentieth century. The ethnic composition varies across the state according to the various sites of settlement of each wave of immigrants. We analyzed the frequency of the CCR5 Delta 32 allele of the CCR5 chemokine receptor, which is considered a Caucasian marker, in five sample sets from the population. Four were collected in Porto Velho, the state capital and the site of several waves of migration. Of these, two, from the Hospital de Base were comprised of HB Mothers and HB Newborns presenting allele frequencies of 3.5% and 3.1%, respectively, a third from the peri-urban neighborhoods of Candelaria/Bate-Estaca (1.8%), whereas a fourth, from the Research Center on Tropical Medicine/CEPEM (0.6%), was composed of malaria patients under treament. The fifth sample (3.4%) came from the inland Quilombola village of Pedras Negras. Two homozygous individuals (CCR5 Delta 32/CCR5 Delta 32) were detected among the HB Mother samples. The frequency of this allele was heterogeneous and higher where the European inflow was more pronounced. The presence of the allele in Pedras Negras revealed European miscegenation in a community largely comprising Quilombolas.

Prevalence of celiac disease among blood donors in Sao Paulo - the most populated city in Brazil

OBJECTIVE: Celiac disease is a permanent enteropathy caused by the ingestion of gluten, which leads to an immune-mediated inflammation of the small intestine mucosa. The prevalence of celiac disease varies among different nations and ethnic backgrounds, and its diversity is determined by genetic and environmental factors. Sao Paulo city is one of the largest cities in the world, with a vast population and an important history of internal migratory flow from other Brazilian regions, as well as immigration from other, primarily European, countries, resulting in significant miscegenation. The aim of the present study was to estimate the prevalence of adults with undiagnosed celiac disease among blood donors of Sao Paulo by collecting information on the ancestry of the population studied. METHODS: The prevalence of celiac disease was assessed by screening for positive IgA transglutaminase and IgA endomysium antibodies in 4,000 donors (volunteers) in the Fundacao Pro-Sangue Blood Center of Sao Paulo, Sao Paulo, Brazil. The antibody-positive subjects were asked to undergo a small bowel biopsy. RESULTS: Of the 4,000 subjects, twenty-four had positive tests, although both antibody tests were not always concordant. For example, ten subjects were positive for IgA tissue transglutaminase only. In twenty-one positive patients, duodenal biopsies were performed, and the diagnosis of celiac disease was confirmed in fourteen patients (Marsh criteria modified by Oberhuber). In this group, 67% claimed to have European ancestry, mainly from Italy, Portugal and Spain. CONCLUSION: The prevalence of celiac disease is at least 1: 286 among supposedly healthy blood bank volunteers in Sao Paulo, Brazil.

Prevalence of celiac disease among blood donors in São Paulo: the most populated city in Brazil

OBJECTIVE: Celiac disease is a permanent enteropathy caused by the ingestion of gluten, which leads to an immunemediated inflammation of the small intestine mucosa. The prevalence of celiac disease varies among different nations and ethnic backgrounds, and its diversity is determined by genetic and environmental factors. São Paulo city is one of the largest cities in the world, with a vast population and an important history of internal migratory flow from other Brazilian regions, as well as immigration from other, primarily European, countries, resulting in significant miscegenation. The aim of the present study was to estimate the prevalence of adults with undiagnosed celiac disease among blood donors of São Paulo by collecting information on the ancestry of the population studied. METHODS: The prevalence of celiac disease was assessed by screening for positive IgA transglutaminase and IgA endomysium antibodies in 4,000 donors (volunteers) in the Fundação Pró-Sangue Blood Center of São Paulo, São Paulo, Brazil. The antibody-positive subjects were asked to undergo a small bowel biopsy. RESULTS: Of the 4,000 subjects, twenty-four had positive tests, although both antibody tests were not always concordant. For example, ten subjects were positive for IgA tissue transglutaminase only. In twenty-one positive patients, duodenal biopsies were performed, and the diagnosis of celiac disease was confirmed in fourteen patients (Marsh criteria modified by Oberhuber). In this group, 67% claimed to have European ancestry, mainly from Italy, Portugal and Spain. CONCLUSION: The prevalence of celiac disease is at least 1:286 among supposedly healthy blood bank volunteers in São Paulo, Brazil.