914 resultados para Leonard, Clifford M.


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Last Will and Testament of Owen Clifford (copy) of the Township of Grantham, Sept. 23, 1870.

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Indenture between Richard Leonard, sheriff of the District of Niagara (regarding lands seized from John Donald McKay) to Robert Dickson. The land consists of ½ an acre located in Lot no. 96 in the Town of Niagara – instrument no. 8600. This was recorded on May 4th, 1832 in Book N, folio 276- 277 in the registry of Lincoln and Haldimand Counties, Oct. 13, 1824.

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In his February 10, 2012 interview with Robert Ryals, Leonard Hewell “Kip” Carter details growing up in the South during segregation and the Civil Rights Movement, as well as his life as political aide/campaign treasurer to Newt Gingrich. Included are details of his college education at UNC-Chapel Hill – classes, professor, and the Red Scare. Carter shares the history of his friendship and working relationship with Newt Gingrich, the scandals Gingrich faced, and the ultimate end of their relationship. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program.

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Foram estudadas as respostas plásticas em duas espécies nativas. em G. hymenifolia, não foram verificadas modificações morfológicas significativas, exceto quanto ao conteúdo de amido de reserva, que foram menores nos lotes capacidade de campo desnutrido (CCD) e alagamento desnutrido (ALD). em Genipa americana os indivíduos do lote (CCN - capacidade de campo nutrido) exibiram raízes adventícias com aerênquima distinto, mais freqüentes nas plantas do lote controle submetidas ao alagamento (ALN - alagado nutrido). Nessa última espécie, nos lotes ALN, verificou-se o surgimento de aerênquima lisógeno no caule, além da hipertrofia lenticelar. A diversidade de respostas às condições de alagamento, aliada à uma larga ocorrência de populações de Genipa americana em áreas sazonalmente inundadas, como por exemplo no Pantanal de Miranda-MS, sugere um complexo de interações entre caractes adaptativos morfológicos e fisiológicos, sendo o potencial gênico fundamental neste tipo de resposta.

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Z(2)-gradings of Clifford algebras are reviewed and we shall be concerned with an alpha-grading based on the structure of inner automorphisms, which is closely related to the spacetime splitting, if we consider the standard conjugation map automorphism by an arbitrary, but fixed, splitting vector. After briefly sketching the orthogonal and parallel components of products of differential forms, where we introduce the parallel [orthogonal] part as the space [time] component, we provide a detailed exposition of the Dirac operator splitting and we show how the differential operator parallel and orthogonal components are related to the Lie derivative along the splitting vector and the angular momentum splitting bivector. We also introduce multivectorial-induced alpha-gradings and present the Dirac equation in terms of the spacetime splitting, where the Dirac spinor field is shown to be a direct sum of two quaternions. We point out some possible physical applications of the formalism developed.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Ciências Sociais - FFC

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Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits marked intertumoural heterogeneity, with at least four distinct molecular variants, previous attempts to identify targets for therapy have been underpowered because of small samples sizes. Here we report somatic copy number aberrations (SCNAs) in 1,087 unique medulloblastomas. SCNAs are common in medulloblastoma, and are predominantly subgroup-enriched. The most common region of focal copy number gain is a tandem duplication of SNCAIP, a gene associated with Parkinson's disease, which is exquisitely restricted to Group 4 alpha. Recurrent translocations of PVT1, including PVT1-MYC and PVT1-NDRG1, that arise through chromothripsis are restricted to Group 3. Numerous targetable SCNAs, including recurrent events targeting TGF-beta signalling in Group 3, and NF-kappa B signalling in Group 4, suggest future avenues for rational, targeted therapy.

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M.

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Signatur des Originals: S 36/F01023

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Signatur des Originals: S 36/F01024

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Signatur des Originals: S 36/F08254