995 resultados para Keller, Albert von, 1844-1920.


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UANL

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BACKGROUNDS: Cyclophosphamide and high-dose steroids have been used as limited induction therapy in progressive IgA nephropathy (IgAN) to reduce the loss of renal function and proteinuria. We evaluated the effect of cyclophosphamide pulses (CyP) and mycophenolic acid (MPA) as sequential therapy on renal function in patients with progressive IgAN. METHODS: Twenty patients with progressive IgAN and advanced renal failure (median GFR 22 ml/min per 1.73 m2) and further disease activity (triangle downGFR -0.8 ml/min per month) after cyclophosphamide (CyP; n = 18) or steroid pulse therapy (n = 2) were treated with mycophenolate mofetil 1 g per day for a median of 27 months. RESULTS: The monthly loss of renal function was significantly reduced in linear regression analysis from -2.4 ml/min before CyP to -0.12 ml/min with CyP/MPA (p = 0.0009). Estimated renal survival time was significantly prolonged by a median of 65 months (p = 0.0014). Proteinuria decreased significantly from 1.7 to 0.4 g/l during MPA treatment (p = 0.015). In Cox regression analysis, only proteinuria >1.0 g/l was an independent risk factor for doubling of creatinine during CyP/MPA treatment (p = 0.03). CONCLUSION: A sequential therapy with CyP/MPA may arrest or slow down the loss of renal function and reduces proteinuria even in patients who passed the so called 'point of no return' with progressive IgAN.

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Welsch (Projektbearbeiter): Berlin, 16. Oktober 1848: Aus einer Arbeiterdemonstration entwickeln sich Barrikadenkämpfe mit der Bürgerwehr. Insgesamt 12 Tote, zahlreiche Verwundete

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u.a.: Besuch der Tante Frau Wüstenfeld in Frankfurt; Philosophie; Kontakt mit Jörg Herwegh und Richard Wagner; Studium der Rechtswissenschaft, Medizin und Philologie; Buddhismus; Lehrwerk der Tibetischen und Mongolischen Sprache von Isaac Jacob Schmidt in Petersburg; Tranksrit-, Zend-, Parsi- und Tibetische Manuskripte im Britischen Museum; 2. Auflage der "Welt als Wille und Vorstellung" von 1844 in der Stadtbibliothek Zürich; Metaphysik der Geschlechtsliebe; Manuskript "Geschichte der Geschlechtsliebe"; Immanuel Kant; Über die vierfache Wurzel des Satzes vom zureichenden Grunde;

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Reprinted from Globus, v. 79, no. 19.

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1. ptie. Monuments de la vallée du Polvar-Roud.--2. ptie. Monuments de Persépolis.--3. ptie. La sculpture persépolitaine.--4. ptie. Les monuments voutés de l'époque achéménide.--5. ptie. Monuments parthes et sassanides.

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National Highway Safety Bureau, Washington, D.C.