Blair's outlines of ancient history : on a new plan, embracing biographical notices of illustrious persons, generalviews of the geography, population, politics, religion, military and naval affairs, arts, literature, manners, customs, and society of ancient nations, a chronological table, and a dictionary of proper names that occur in the work.

Mode of access: Internet.

L. Annaei Senecae Philosophi opera, ad optimas editiones collata. Praemittitur notitia literaria studiis societatis Bipontinae.

Mode of access: Internet.

Tables chronologiques : qui embrassent toutes les parties de l'histoire universelle, année par année, depuis la création du monde jusqu'en mil sept cent soixante-huit /

Includes indexes.

Blair's chronological and historical tables : from the creation to the present time, with additions and corrections from the most authentic writers, including the computation of St. Paul, as connecting the period from the exode to the temple.

"The present volume has been reconstructed from the folio edition by a literary friend [John Sharpe] ... the ... revision of the manuscript ... having been intrusted to myself."--Sir Henry Ellis, in preface (dated 1844) cf. also Lowndes.

Remarks on the Letter from a gentleman in Boston, to a Unitarian clergyman of that city : and the Reply, and Review of the same.

Mode of access: Internet.

Tystiolaeth y credadyn am ei hawl i'r nefoedd: neu gynnyg byr tu ag at Gysur Crist'nogol,neu lawenydd ysbrydol.A gyfiethwyd o'r trydydd argraffiad yn Saesneg,

A translation of: The Christian life.

A history of the commonwealth of Kentucky.

Narrative closes in the midst of the war of 1812.

Either interleukin-12 or interferon-gamma can correct the dendritic cell defect induced by transforming growth factor beta(1) in patients with myeloma

The poor response to immunotherapy in patients with multiple myeloma (MM) indicates that a better understanding of any defects in the immune response in these patients is required before effective therapeutic strategies can be developed. Recently we reported that high potency (CMRF44(+)) dendritic cells (DC) in the peripheral blood of patients with MM failed to significantly up-regulate the expression of the B7 co-stimulatory molecules, CD80 and CD86, in response to an appropriate signal from soluble trimeric human CD40 ligand. This defect was caused by transforming growth factor beta(1) (TGFbeta(1)) and interleukin (IL)-10, produced by malignant plasma cells, and the defect was neutralized in vitro with anti-TGFbeta(1). As this defect could impact on immunotherapeutic strategies and may be a major cause of the failure of recent trials, it was important to identify a more clinically useful agent that could correct the defect in vivo. In this study of 59 MM patients, the relative and absolute numbers of blood DC were only significantly decreased in patients with stage III disease and CD80 up-regulation was reduced in both stage I and stage III. It was demonstrated that both IL-12 and interferon-gamma neutralized the failure to stimulate CD80 up-regulation by huCD40LT in vitro. IL-12 did not cause a change in the distribution of DC subsets that were predominantly myeloid (CD11c+ and CDw123-) suggesting that there would be a predominantly T-helper cell type response. The addition of IL-12 or interferon-gamma to future immunotherapy trials involving these patients should be considered.

Transiting Exoplanet Studies and Community Targets for JWST's Early Release Science Program

The James Webb Space Telescope (JWST) will likely revolutionize transiting exoplanet atmospheric science, due to a combination of its capability for continuous, long duration observations and its larger collecting area, spectral coverage, and spectral resolution compared to existing space-based facilities. However, it is unclear precisely how well JWST will perform and which of its myriad instruments and observing modes will be best suited for transiting exoplanet studies. In this article, we describe a prefatory JWST Early Release Science (ERS) Cycle 1 program that focuses on testing specific observing modes to quickly give the community the data and experience it needs to plan more efficient and successful transiting exoplanet characterization programs in later cycles. We propose a multi-pronged approach wherein one aspect of the program focuses on observing transits of a single target with all of the recommended observing modes to identify and understand potential systematics, compare transmission spectra at overlapping and neighboring wavelength regions, confirm throughputs, and determine overall performances. In our search for transiting exoplanets that are well suited to achieving these goals, we identify 12 objects (dubbed “community targets”) that meet our defined criteria. Currently, the most favorable target is WASP-62b because of its large predicted signal size, relatively bright host star, and location in JWST's continuous viewing zone. Since most of the community targets do not have well-characterized atmospheres, we recommend initiating preparatory observing programs to determine the presence of obscuring clouds/hazes within their atmospheres. Measurable spectroscopic features are needed to establish the optimal resolution and wavelength regions for exoplanet characterization. Other initiatives from our proposed ERS program include testing the instrument brightness limits and performing phase-curve observations. The latter are a unique challenge compared to transit observations because of their significantly longer durations. Using only a single mode, we propose to observe a full-orbit phase curve of one of the previously characterized, short-orbital-period planets to evaluate the facility-level aspects of long, uninterrupted time-series observations.

Exact Solution of Bayes and Minimax Change-Detection Problems

The challenge of detecting a change in the distribution of data is a sequential decision problem that is relevant to many engineering solutions, including quality control and machine and process monitoring. This dissertation develops techniques for exact solution of change-detection problems with discrete time and discrete observations. Change-detection problems are classified as Bayes or minimax based on the availability of information on the change-time distribution. A Bayes optimal solution uses prior information about the distribution of the change time to minimize the expected cost, whereas a minimax optimal solution minimizes the cost under the worst-case change-time distribution. Both types of problems are addressed. The most important result of the dissertation is the development of a polynomial-time algorithm for the solution of important classes of Markov Bayes change-detection problems. Existing techniques for epsilon-exact solution of partially observable Markov decision processes have complexity exponential in the number of observation symbols. A new algorithm, called constellation induction, exploits the concavity and Lipschitz continuity of the value function, and has complexity polynomial in the number of observation symbols. It is shown that change-detection problems with a geometric change-time distribution and identically- and independently-distributed observations before and after the change are solvable in polynomial time. Also, change-detection problems on hidden Markov models with a fixed number of recurrent states are solvable in polynomial time. A detailed implementation and analysis of the constellation-induction algorithm are provided. Exact solution methods are also established for several types of minimax change-detection problems. Finite-horizon problems with arbitrary observation distributions are modeled as extensive-form games and solved using linear programs. Infinite-horizon problems with linear penalty for detection delay and identically- and independently-distributed observations can be solved in polynomial time via epsilon-optimal parameterization of a cumulative-sum procedure. Finally, the properties of policies for change-detection problems are described and analyzed. Simple classes of formal languages are shown to be sufficient for epsilon-exact solution of change-detection problems, and methods for finding minimally sized policy representations are described.

Catalogue des vases, colonnes, tables de marbres rares, figures de bronze, porcelaines de choix, laques, meubles précieux, pendules, lustres... et autres effets importants qui composent le cabinet de feu M. le duc d'Aumont . Par P. F. Julliot fils, & A. J. Paillet. La vente se fera le 12 D��cembre 1782...

[Vente. Art. 1782-12-12. Paris]

Nijden terwellisten sanain muoto, 2 Tim. 1:13. Sijnä järjestyxesä kuin d. Lutheruxen Catechismus sen päkappaleisa sisällänspitä, nijden enimmäin catechismuxen selittäitten johdatuxen jälkeen, edeswetänyt ja kokoonpannut yxinkertaisisa kysymyxisä ja wastauxisa. Wuonna 1782. Eric Frosterus v. past. ja cappalainen Haukiputan kappelilla, Iin pitäjäsä

Arkit: A-M8 N6

Nijden terwellisten sanain muoto, 2 Tim. 1:13. Sijnä järjestyxesä kuin d. Lutheruxen Catechismus sen päkappaleisa sisällänspitä, nijden enimmäin catechismuxen selittäitten johdatuxen jälkeen, edeswetänyt ja kokoonpannut yxinkertaisisa kysymyxisä ja wastauxisa. Wuonna 1782. Eric Frosterus v. past. ja cappalainen Haukiputan kappelilla, Iin pitäjäsä

Arkit: A-M8 N6