994 resultados para Harold B. Crosby


Relevância:

80.00% 80.00%

Publicador:

Resumo:

Issued also as House doc. 429, U.S., 63d Cong., 2d sess

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Includes bibliography.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

With a supplement by Charlotte L. Melvin on The story of Aroostook, Maine's last frontier.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Added t.p.: The life of David Hume, Esq. written by himself: v. 1, p. [v]-xviii.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Cover title.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

40.00% 40.00%

Publicador:

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Various memorial addresses.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

This is part of the finding aid to the Graduate School and University Center (GSUC) Archives. Record Group V-B is the papers of Harold M. Proshansky from when he was president of the GSUC (1972-1990).

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Pygmalion (1913), by George Bernard Shaw (1856-1950), has many studies in literary criticism. However, this study brings a new interpretation to Shaw s play based on Harold Bloom s theory and methodology, that is, the anxiety of influence and the dialectic of revisionism. Through the analysis of poetic influence and the dialectic of love, we can see that Pygmalion represents an apophrades in relation to William Shakespeare s The Taming of the Shrew (1593) and Ovid s myth of Pygmalion and Galatea in Metamorphosis (c. 14), which creates a family romance between the three stories. Shaw s play surpasses The Taming of the Shrew when it shows the possibility of the relation between this parent poem and Ovid s myth, which it is also its parent poem, and because it represents a strong misreading of Shakespeare s play as well as of Ovid s myth.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Apolipoprotein B (apoB) mRNA editing catalyzed by apoB mRNA editing catalytic subunit 1 (APOBEC-1) has been proposed to be a nuclear process. To test this hypothesis, the subcellular distribution of hemagglutinin-(HA) tagged APOBEC-1 expressed in transiently transfected hepatoma cells was determined by indirect immunofluorescence microscopy. HA-APOBEC-1 was detected in both the nucleus and cytoplasm of rat and human hepatoma cells. Mutagenesis of APOBEC-1 demonstrated that the N-terminal 56 amino acids (1–56) were necessary for the nuclear distribution of APOBEC-1, but this region did not contain a functional nuclear localization signal (NLS). However, we identified a 24-amino acid domain in the C terminus of APOBEC-1 with characteristics of a cytoplasmic retention signal (CRS) or a nuclear export signal (NES). These data suggest, therefore, that the nuclear import of APOBEC-1 may not be mediated by a positive NLS; rather, it may be achieved by overcoming the effect of a CRS/NES. We also demonstrated that the nuclear distribution of APOBEC-1 occurred only in cell lines that were capable of editing apoB RNA. We propose that the cellular distribution of APOBEC-1 is determined by multiple domains within this protein, and a nuclear localization of the enzyme may be regulated by cell type-specific factors that render these cells uniquely editing competent.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Hepatitis B viruses (HBV) and related viruses, classified in the Hepadnaviridae family, are found in a wide variety of mammals and birds. Although the chimpanzee has been the primary experimental model of HBV infection, this species has not been considered a natural host for the virus. Retrospective analysis of 13 predominantly wild-caught chimpanzees with chronic HBV infection identified a unique chimpanzee HBV strain in 11 animals. Nucleotide and derived amino acid analysis of the complete HBV genome and the gene coding for the hepatitis B surface antigen (S gene) identified sequence patterns that could be used to reliably identify chimpanzee HBV. This analysis indicated that chimpanzee HBV is distinct from known human HBV genotypes and is closely related to HBVs previously isolated from a chimpanzee, gibbons, gorillas, and orangutans.