L'art de sentir et de juger en materie de gout ...: tome premier [-second] /

BNP

A tract upon dyspepsy, or indigestion, and the hypochondriac disease : and upon the inflammatory or regular gout, and the atonic, irregular, or flying gout ... /

Mode of access: Internet.

Temple du Gout et poésies melées /

Mode of access: Internet.

A dissertation on gout; exhibiting a new view of the origin, nature, cause, cure, and prevention of that afflicting disease; illustrated and confirmed by a variety of original and communicated cases.

Mode of access: Internet.

Perse traduit en vers françois et accomodé au gout présent,

Latin text and French verse translation on opposite pages.

Le menage universel de la ville et des champs, et le jardinier : accommodez au gout du tems; ou la maniere facile d'aprêter tout ce qui est necessaire ...

Engraved frontispiece.

Le menage des champs, et le jardinier françois accomodez au gout du temps : dans lesquelles on peut apprendre facilement à aprêter tout ce qui est necessaire pour l'usage de la vie à la campagne ... avec un traité de la chasse & de la pêche.

Goldsmiths'-Kress no. 04667.3-2, suppl.

Nouvelle bibliothèque d'un homme de gout : ou tableau de la littérature ancienne et moderne, dans lequel on fait connoître l'espirt de tous les livres qui ont paru dans tous les genres jusqu'en 1797; avec un jugement sommaire et impartial sur chaque ouvrage, et l'indication des différentes éditions qui en ont été faites, tant en France qu'en pays étranger /

Mode of access: Internet.

Nouvelle bibliothèque d'un homme de gout, ou Tableau de la littérature ancienne et moderne, étrangere & nationale, dans lequel on expose le sujet, & l'on fait connoître l'esprit de tous les livres qui ont paru dans tous les siecles, sur tous les genres, & dans toutes les langue, avec un jugement court, précis, clair et impartial,

First edition in 2 vols., Avignon, 1772, has title: Bibliothèque d'un homme de goût.

Les ornemens de la mémoire, ou Les traits brillans des poëtes Francais les plus célébres; avec des dissertations sur chaque genre de style. Ouvrage propre a orner l'esprit de la jeunesse, et a former son gout.

Mode of access: Internet.

Catalogue d'un cabinet exquis de desseins, tant en couleurs, que lavez & au crayon; de presque tous les plus fameux maîtres des paysbas. Formé avec gout, pendant plus de cinquante années, et délaissé par monsieur Sybrand Feitama. Dont la vente se sera le lundi 16 d'Octobre 1758, & jours suivans ...

Priced in manuscript.

Normal HPRT coding region in a male with gout due to HPRT deficiency (Brief Communication)

A deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT; EC 2.4.2.8) is associated with a spectrum of disease that ranges from gouty arthritis (OMIM 300323) to the more severe Lesch-Nyhan syndrome (OMIM 300322). To date, all cases of HPRT deficiency have shown a mutation within the HPRT cDNA. In the present study of an individual with gout due to HPRT deficiency, we found a normal HPRT cDNA sequence. This is the first study to provide an example of HPRT deficiency which appears to be due to a defect in the regulation of the gene. © 2005 Elsevier Inc. All rights reserved.

A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis

Though difficult, the study of gene-environment interactions in multifactorial diseases is crucial for interpreting the relevance of non-heritable factors and prevents from overlooking genetic associations with small but measurable effects. We propose a "candidate interactome" (i.e. a group of genes whose products are known to physically interact with environmental factors that may be relevant for disease pathogenesis) analysis of genome-wide association data in multiple sclerosis. We looked for statistical enrichment of associations among interactomes that, at the current state of knowledge, may be representative of gene-environment interactions of potential, uncertain or unlikely relevance for multiple sclerosis pathogenesis: Epstein-Barr virus, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, cytomegalovirus, HHV8-Kaposi sarcoma, H1N1-influenza, JC virus, human innate immunity interactome for type I interferon, autoimmune regulator, vitamin D receptor, aryl hydrocarbon receptor and a panel of proteins targeted by 70 innate immune-modulating viral open reading frames from 30 viral species. Interactomes were either obtained from the literature or were manually curated. The P values of all single nucleotide polymorphism mapping to a given interactome were obtained from the last genome-wide association study of the International Multiple Sclerosis Genetics Consortium & the Wellcome Trust Case Control Consortium, 2. The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology. However, in line with recent data on the coexistence of common and unique strategies used by viruses to perturb the human molecular system, also other viruses have a similar potential, though probably less relevant in epidemiological terms. © 2013 Mechelli et al.

Novel ANKH amino terminus mutation (Pro5Ser) associated with early-onset calcium pyrophosphate disease with associated phosphaturia

This report describes a 32-year-old woman presenting since childhood with progressive calcium pyrophosphate disease (CPPD), characterized by severe arthropathy and chondrocalcinosis involving multiple peripheral joints and intervertebral disks. Because ANKH mutations have been previously described in familial CPPD, the proband's DNA was assessed at this locus by direct sequencing of promoter and coding regions and revealed 3 sequence variants in ANKH. Sequences of exon 1 revealed a novel isolated nonsynonymous mutation (c.13 C>T), altering amino acid in codon 5 from proline to serine (CCG>TCG). Sequencing of parental DNA revealed an identical mutation in the proband's father but not the mother. Subsequent clinical evaluation demonstrated extensive chondrocalcinosis and degenerative arthropathy in the proband's father. In summary, we report a novel mutation, not previously described, in ANKH exon 1, wherein serine replaces proline, in a case of early-onset severe CPPD associated with metabolic abnormalities, with similar findings in the proband's father.