Desenvolvimento de um sistema de verificação dosimétrica tridimensional utilizando Solução Fricke gel na aplicação para a verificação da Radioterapia em Arco Modulado Volumétrico (VMAT) nos tratamentos com movimentação do alvo pela respiração

Tese (Doutorado em Tecnologia Nuclear)

Mental health: How well are occupational therapists equipped for a changed practice environment?

No Abstract

Occurrence of Diodon eydouxii (Actinopterygii: Diodontidae), in the Azores and comparison with Pacific specimens

A specimen of porcupine fish was collected by a fisherman at Terceira Island, Azores (north-eastern Atlantic), and identified as the pelagic porcupinefish, Diodon eydouxii Brisout de Barneville, 1846, a species recently recorded for the first time from the Azores. This record, together with an examination of the first reported specimen, allowed us to compare the external morphology with Pacific specimens. The possibility of this species to be relatively common in the Azores is discussed.

Avaliação de um biodosímetro de radiação ionizante - Comparação Dosimétrica

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade de Nova de Lisboa para complementar os requerimentos para a obtenção do grau de Mestre em Engenharia Biomédica

Experimental Model of Gene Transfection in Healthy Canine Myocardium: Perspectives of Gene Therapy for Ischemic Heart Disease

OBJECTIVE: To assess the transfection of the gene that encodes green fluorescent protein (GFP) through direct intramyocardial injection. METHODS: The pREGFP plasmid vector was used. The EGFP gene was inserted downstream from the constitutive promoter of the Rous sarcoma virus. Five male dogs were used (mean weight 13.5 kg), in which 0.5 mL of saline solution (n=1) or 0.5 mL of plasmid solution containing 0.5 µg of pREGFP/dog (n=4) were injected into the myocardium of the left ventricular lateral wall. The dogs were euthanized 1 week later, and cardiac biopsies were obtained. RESULTS: Fluorescence microscopy showed differences between the cells transfected and not transfected with pREGFP plasmid. Mild fluorescence was observed in the cardiac fibers that received saline solution; however, the myocardial cells transfected with pREGFP had overt EGFP expression. CONCLUSION: Transfection with the EGFP gene in healthy canine myocardium was effective. The reproduction of this efficacy using vascular endothelial growth factor (VEGF) instead of EGFP aims at developing gene therapy for ischemic heart disease.

Der Tropfen als Reaktor : emulsionsgestützte Fällung von Nanopartikeln am Beispiel der Synthese von Zinkoxid

Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014