The whaling issue: Conservation, confusion, and casuistry

Morishita’s “multiple analysis”of the whaling issue [Morishita J. Multiple analysis of the whaling issue: Understanding the dispute by a matrix. Marine Policy 2006;30:802–8] is essentially a restatement of the Government of Japan’s whaling policy, which confuses the issue through selective use of data, unsubstantiated facts, and the vilification of opposing perspectives. Here, we deconstruct the major problems with Morishita’s article and provide an alternative view of the whaling dispute. For many people in this debate, the issue is not that some whales are not abundant, but that the whaling industry cannot be trusted to regulate itself or to honestly assess the status of potentially exploitable populations. This suspicion has its origin in Japan’s poor use of science, its often implausible stock assessments, its insistence that culling is an appropriate way to manage marine mammal populations, and its relatively recent falsification of whaling and fisheries catch data combined with a refusal to accept true transparency in catch and market monitoring. Japanese policy on whaling cannot be viewed in isolation, but is part of a larger framework involving a perceived right to secure unlimited access to global marine resources. Whaling is inextricably tied to the international fisheries agreements on which Japan is strongly dependent; thus, concessions made at the IWC would have potentially serious ramifications in other fora.

Effects of replica running shoes upon external forces and muscle activity during running

Twelve participants ran (9 km . h(-1)) to test two types of running shoes: replica and original shoes. Ground reaction force, plantar pressure and electromyographic activity were recorded. The shoes were tested randomly and on different days. Comparisons between the two experimental conditions were made by analysis of variance (ANOVA) test (P <= 0.05). The time to first peak, loading rate of the first peak and impulse of the first 75 ms of stance were significantly different between the shoes (P <= 0.05), revealing an increase of impact forces for the replica shoes. The peak plantar pressure values were significantly higher (P <= 0.05) when wearing replica shoes. During running, the contact area was significantly smaller (P <= 0.05) for the replica shoe. The electromyographic activity of the analysed muscles did not show changes between the two shoes in running. These findings suggest that the use of replica running shoes can increase the external load applied to the human body, but may not change the muscle activity pattern during locomotion. This new mechanical situation may increase the risk of injuries in these movements.

Essays on Unemployment Insurance

Can the potential availability of unemployment insurance (UI) affect the behavior of employed workers and the duration of their employment spells? After discussing few straightforward reasons why UI may affect employment duration, I apply a regression kink design (RKD) to address this question using linked employer-employee data from the Brazilian labor market. Exploiting the UI schedule, I find that potential benefit level significantly affects the duration of employment spells. This effect is local to low skilled workers and, surprisingly, indicates that a 1\% increase in unemployment benefits increases job duration by around 0.3\%. Such result is driven by the fact that higher UI decreases the probability of job quits, which are not covered by UI in Brazil. These estimates are robust to permutation tests and a number of falsification tests. I develop a reduced-form welfare formula to assess the economic relevance of this result. Based on that, I show that the positive effect on employment duration implies in a higher optimal benefit level. Moreover, the formula shows that the elasticity of employment duration impacts welfare just with the same weight as the well-known elasticity of unemployment duration to benefit level.

Modelling and simulating in systems biology: an approach based on multi-agent systems

Systems Biology is an innovative way of doing biology recently raised in bio-informatics contexts, characterised by the study of biological systems as complex systems with a strong focus on the system level and on the interaction dimension. In other words, the objective is to understand biological systems as a whole, putting on the foreground not only the study of the individual parts as standalone parts, but also of their interaction and of the global properties that emerge at the system level by means of the interaction among the parts. This thesis focuses on the adoption of multi-agent systems (MAS) as a suitable paradigm for Systems Biology, for developing models and simulation of complex biological systems. Multi-agent system have been recently introduced in informatics context as a suitabe paradigm for modelling and engineering complex systems. Roughly speaking, a MAS can be conceived as a set of autonomous and interacting entities, called agents, situated in some kind of nvironment, where they fruitfully interact and coordinate so as to obtain a coherent global system behaviour. The claim of this work is that the general properties of MAS make them an effective approach for modelling and building simulations of complex biological systems, following the methodological principles identified by Systems Biology. In particular, the thesis focuses on cell populations as biological systems. In order to support the claim, the thesis introduces and describes (i) a MAS-based model conceived for modelling the dynamics of systems of cells interacting inside cell environment called niches. (ii) a computational tool, developed for implementing the models and executing the simulations. The tool is meant to work as a kind of virtual laboratory, on top of which kinds of virtual experiments can be performed, characterised by the definition and execution of specific models implemented as MASs, so as to support the validation, falsification and improvement of the models through the observation and analysis of the simulations. A hematopoietic stem cell system is taken as reference case study for formulating a specific model and executing virtual experiments.

Law and science: risk assessment and risk management in the WTO agreement on the application of sanitary and phytosanitary measures

Assessing and managing risks relating to the consumption of food stuffs for humans and to the environment has been one of the most complex legal issues in WTO law, ever since the Agreement on Sanitary and Phytosanitary Measures was adopted at the end of the Uruguay Round and entered into force in 1995. The problem was expounded in a number of cases. Panels and the Appellate Body adopted different philosophies in interpreting the agreement and the basic concept of risk assessment as defined in Annex A para. 4 of the Agreement. Risk assessment entails fundamental question on law and science. Different interpretations reflect different underlying perceptions of science and its relationship to the law. The present thesis supported by the Swiss National Research Foundation undertakes an in-depth analysis of these underlying perceptions. The author expounds the essence and differences of positivism and relativism in philosophy and natural sciences. He clarifies the relationship of fundamental concepts such as risk, hazards and probability. This investigation is a remarkable effort on the part of lawyer keen to learn more about the fundamentals based upon which the law – often unconsciously – is operated by the legal profession and the trade community. Based upon these insights, he turns to a critical assessment of jurisprudence both of panels and the Appellate Body. Extensively referring and discussing the literature, he deconstructs findings and decisions in light of implied and assumed underlying philosophies and perceptions as to the relationship of law and science, in particular in the field of food standards. Finding that both positivism and relativism does not provide adequate answers, the author turns critical rationalism and applies the methodologies of falsification developed by Karl R. Popper. Critical rationalism allows combining discourse in science and law and helps preparing the ground for a new approach to risk assessment and risk management. Linking the problem to the doctrine of multilevel governance the author develops a theory allocating risk assessment to international for a while leaving the matter of risk management to national and democratically accountable government. While the author throughout the thesis questions the possibility of separating risk assessment and risk management, the thesis offers new avenues which may assist in structuring a complex and difficult problem

A case study approach to estimating the burden of research misconduct in publicly funded medical research

The economic impact of research misconduct in medical research has been unexplored. While research misconduct in publicly funded medical research has increasingly been the object of discussion, public policy debate, government and institutional action, and scientific research, the costs of research misconduct have been unexamined. The author develops a model to estimate the per case cost of research misconduct, specifically the costs of fabrication, falsification, and plagiarism, in publicly funded medical research. Using the database of Research Misconduct Findings maintained by the Office of Research Integrity, Department of Health and Human Services, the model is used to estimate costs of research misconduct in public funded medical research among faculty during the period 2000-2005.^

La reconstrucción histórica en el "Revisionismo" de David Irving

En este trabajo se plantea, más allá de examinar las tesis principales del "revisionismo", la propia naturaleza del conocimiento histórico. ¿Son válidas todas las interpretaciones de un hecho histórico? ¿Se trata en tales casos de "otra lectura", de una "versión alternativa", es decir, de otra apreciación de los datos disponibles? ¿Cómo saber cuando hay mala interpretación deliberada o falsificación de la evidencia? ¿Puede detectarse si la argumentación tendenciosa es deshonesta? El "revisionismo histórico" se ha definido a sí mismo como una corriente historiográfica que ofrece otra versión de Hitler y su régimen. Cerca de una veintena de autores, desde los años cuarenta del siglo XX, se adscriben en esta tendencia, algunos de los cuales han desplegado una sostenida actividad y han logrado una llamativa repercusión en los medios de difusión. Este es el caso de David Irving. Autor de más de treinta libros, artículos, conferencias y discursos dedicados al III Reich, ha pasado largos años de su vida rastreando y estudiando archivos alemanes. Pero muy lejos de constituir un nuevo enfoque historiográfico del nazismo, el "revisionismo" de David Irving está imbuido de política e ideología y sus métodos de trabajo incluyen la adulteración y la distorsión intencional de la historia.

Las perplejidades de un lector modelo: Ensayo y ficción en Ricardo Piglia

A partir de la lectura de una serie de atribuciones erróneas que atraviesa tres ensayos de Ricardo Piglia sobre Macedonio Fernández, este artículo sugiere una hipótesis sobre los alcances de la estrategia de "ficcionalización de la crítica" que caracteriza la ensayística de Piglia y ensaya una evaluación de la reducción, que se opera en ésta, del acontecimiento de la ficción a un efecto de falsificación previsto por una instancia autorial. En el curso de esa tentativa evaluadora, se proponen algunas diferencias entre la ensayística de Piglia y la de Jorge Luis Borges.

En busca del vino genuino. Origen y consecuencias de la Ley Nacional de Vinos de 1904

En el marco de la crisis vitivinícola de principios del siglo XX, se generó, entre los agentes implicados en esa actividad, una discusión sobre sus causas y posibles soluciones. Uno de los cambios propiciados fue la renovación de la legislación que regulaba la agroindustria. Este artículo analiza la génesis de la nueva ley de vinos, sancionada en 1904, con el nº 4363, que reguló la actividad hasta fines de la década de 1930 y constituyó un avance en la definición de vino genuino y otorgó herramientas más eficaces al Estado para reprimir la falsificación del vino. Sin embargo, reforzó el modelo de producción de vino en masa y dejó "espacios" de control vacíos que fueron denunciados por otros sectores relacionados con la agroindustria.

Las perplejidades de un lector modelo: Ensayo y ficción en Ricardo Piglia

A partir de la lectura de una serie de atribuciones erróneas que atraviesa tres ensayos de Ricardo Piglia sobre Macedonio Fernández, este artículo sugiere una hipótesis sobre los alcances de la estrategia de "ficcionalización de la crítica" que caracteriza la ensayística de Piglia y ensaya una evaluación de la reducción, que se opera en ésta, del acontecimiento de la ficción a un efecto de falsificación previsto por una instancia autorial. En el curso de esa tentativa evaluadora, se proponen algunas diferencias entre la ensayística de Piglia y la de Jorge Luis Borges.

En busca del vino genuino. Origen y consecuencias de la Ley Nacional de Vinos de 1904

En el marco de la crisis vitivinícola de principios del siglo XX, se generó, entre los agentes implicados en esa actividad, una discusión sobre sus causas y posibles soluciones. Uno de los cambios propiciados fue la renovación de la legislación que regulaba la agroindustria. Este artículo analiza la génesis de la nueva ley de vinos, sancionada en 1904, con el nº 4363, que reguló la actividad hasta fines de la década de 1930 y constituyó un avance en la definición de vino genuino y otorgó herramientas más eficaces al Estado para reprimir la falsificación del vino. Sin embargo, reforzó el modelo de producción de vino en masa y dejó "espacios" de control vacíos que fueron denunciados por otros sectores relacionados con la agroindustria.

En busca del vino genuino. Origen y consecuencias de la Ley Nacional de Vinos de 1904

En el marco de la crisis vitivinícola de principios del siglo XX, se generó, entre los agentes implicados en esa actividad, una discusión sobre sus causas y posibles soluciones. Uno de los cambios propiciados fue la renovación de la legislación que regulaba la agroindustria. Este artículo analiza la génesis de la nueva ley de vinos, sancionada en 1904, con el nº 4363, que reguló la actividad hasta fines de la década de 1930 y constituyó un avance en la definición de vino genuino y otorgó herramientas más eficaces al Estado para reprimir la falsificación del vino. Sin embargo, reforzó el modelo de producción de vino en masa y dejó "espacios" de control vacíos que fueron denunciados por otros sectores relacionados con la agroindustria.

Las perplejidades de un lector modelo: Ensayo y ficción en Ricardo Piglia

A partir de la lectura de una serie de atribuciones erróneas que atraviesa tres ensayos de Ricardo Piglia sobre Macedonio Fernández, este artículo sugiere una hipótesis sobre los alcances de la estrategia de "ficcionalización de la crítica" que caracteriza la ensayística de Piglia y ensaya una evaluación de la reducción, que se opera en ésta, del acontecimiento de la ficción a un efecto de falsificación previsto por una instancia autorial. En el curso de esa tentativa evaluadora, se proponen algunas diferencias entre la ensayística de Piglia y la de Jorge Luis Borges.

Score optimization and template updating in a biometric technique for authentication in mobiles based on gestures

This article focuses on the evaluation of a biometric technique based on the performance of an identifying gesture by holding a telephone with an embedded accelerometer in his/her hand. The acceleration signals obtained when users perform gestures are analyzed following a mathematical method based on global sequence alignment. In this article, eight different scores are proposed and evaluated in order to quantify the differences between gestures, obtaining an optimal EER result of 3.42% when analyzing a random set of 40 users of a database made up of 80 users with real attempts of falsification. Moreover, a temporal study of the technique is presented leeding to the need to update the template to adapt the manner in which users modify how they perform their identifying gesture over time. Six updating schemes have been assessed within a database of 22 users repeating their identifying gesture in 20 sessions over 4 months, concluding that the more often the template is updated the better and more stable performance the technique presents.

Propuesta, implementación y evaluación de la biometría de firma en el aire como sistema de verificación en teléfonos móviles

En esta tesis doctoral se propone una técnica biométrica de verificación en teléfonos móviles consistente en realizar una firma en el aire con la mano que sujeta el teléfono móvil. Los acelerómetros integrados en el dispositivo muestrean las aceleraciones del movimiento de la firma en el aire, generando tres señales temporales que pueden utilizarse para la verificación del usuario. Se proponen varios enfoques para la implementación del sistema de verificación, a partir de los enfoques más utilizados en biometría de firma manuscrita: correspondencia de patrones, con variantes de los algoritmos de Needleman-Wusch (NW) y Dynamic Time Warping (DTW), modelos ocultos de Markov (HMM) y clasificador estadístico basado en Máquinas de Vector Soporte (SVM). Al no existir bases de datos públicas de firmas en el aire y con el fin de evaluar los métodos propuestos en esta tesis doctoral, se han capturado dos con distintas características; una con falsificaciones reales a partir del estudio de las grabaciones de usuarios auténticos y otra con muestras de usuarios obtenidas en diferentes sesiones a lo largo del tiempo. Utilizando estas bases de datos se han evaluado una gran cantidad de algoritmos para implementar un sistema de verificación basado en firma en el aire. Esta evaluación se ha realizado de acuerdo con el estándar ISO/IEC 19795, añadiendo el caso de verificación en mundo abierto no incluido en la norma. Además, se han analizado las características que hacen que una firma sea suficientemente segura. Por otro lado, se ha estudiado la permanencia de las firmas en el aire a lo largo del tiempo, proponiendo distintos métodos de actualización, basados en una adaptación dinámica del patrón, para mejorar su rendimiento. Finalmente, se ha implementado un prototipo de la técnica de firma en el aire para teléfonos Android e iOS. Los resultados de esta tesis doctoral han tenido un gran impacto, generando varias publicaciones en revistas internacionales, congresos y libros. La firma en el aire ha sido nombrada también en varias revistas de divulgación, portales de noticias Web y televisión. Además, se han obtenido varios premios en competiciones de ideas innovadoras y se ha firmado un acuerdo de explotación de la tecnología con una empresa extranjera. ABSTRACT This thesis proposes a biometric verification technique on mobile phones consisting on making a signature in the air with the hand holding a mobile phone. The accelerometers integrated in the device capture the movement accelerations, generating three temporal signals that can be used for verification. This thesis suggests several approaches for implementing the verification system, based on the most widely used approaches in handwritten signature biometrics: template matching, with a lot of variations of the Needleman- Wusch (NW) and Dynamic Time Warping (DTW) algorithms, Hidden Markov Models (HMM) and Supported Vector Machines (SVM). As there are no public databases of in-air signatures and with the aim of assessing the proposed methods, there have been captured two databases; one. with real falsification attempts from the study of recordings captured when genuine users made their signatures in front of a camera, and other, with samples obtained in different sessions over a long period of time. These databases have been used to evaluate a lot of algorithms in order to implement a verification system based on in-air signatures. This evaluation has been conducted according to the standard ISO/IEC 19795, adding the open-set verification scenario not included in the norm. In addition, the characteristics of a secure signature are also investigated, as well as the permanence of in-air signatures over time, proposing several updating strategies to improve its performance. Finally, a prototype of in-air signature has been developed for iOS and Android phones. The results of this thesis have achieved a high impact, publishing several articles in SCI journals, conferences and books. The in-air signature deployed in this thesis has been also referred in numerous media. Additionally, this technique has won several awards in the entrepreneurship field and also an exploitation agreement has been signed with a foreign company.