947 resultados para Cooney, Michael
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no.5
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Opening statement by Mr Michael Scanlan, Secretary General of the Department of Health & Children at the meeting of the Dáil Committee of Public Accounts on 7th May 2009 Click here to download PDF 37kb
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Objective: "Michael's Game" is a card game which aims at familiarizing healthcare professionals and patients with cognitive therapy of psychotic symptoms. The present study tests the feasibility and the impact of the intervention in naturalistic settings.Methods: 135 patients were recruited in 11 centres. They were assessed pre- and post-tests with the Beck Cognitive Insight Scale (BCIS) and the Peters Delusion Inventory-21 items (PDI-21).Results: Data about 107 patients were included in the entire analyses. Significant improvements were observed on BCIS subscales as well as a reduction of severity of conviction and preoccupation scores on the PDI-21. The intervention has a moderate effect on the PDI-21 preoccupation and conviction as well as the BCIS subscales. Patients who benefit the most from the program are patients who have a low degree of self-reflectiveness and patients who are concomitantly preoccupied by their symptoms.Conclusion: The present study supports the feasibility and effectiveness of "Michael's Game" in naturalistic settings.Practical implications: The game seems to be a useful tool for patients with psychotic disorders. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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En septiembre del año 2010, el Movimiento Nacional Campesino Indígena celebraba su Primer Congreso. Bajo el lema “Somos tierra para alimentar a los pueblos” compartieron y debatieron durante tres días. De este modo, reafirmaron su lucha por la Reforma Agraria Integral y la Soberanía Alimentaria. Se manifestaron por las calles de Buenos Aires para hacer visible “el otro campo”: el de los marginados, ocultados, los pobres, los excluidos del imaginario social, nacional, y también del acceso a los bienes necesarios para el desarrollo una vida digna
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Aquesta memòria es centra en un gran tema de la química orgànica que és la catàlisi asimètrica de les addicions de Michael. Més concretament, en aquest treball s’estudia la enantioselectivitat que proporcionen dos lligand en qüestió, un d’ells basat en metalls i l’altre organocatalític, en unes reaccions de Michael. Així doncs, s’estudiaren dos tipus de sistemes. El primer cas és l’addició de Michael entre 2-tert-butoxicarbonil-1-indanona i tres acceptors de Michael diferents com són la metilvinilcetona, el Nacriloïloxazolidinona i l’azodicarboxilat de di-tert-butil, catalitzat per combinacions de metalls lantànids (majoritariament Yb) amb lligands quirals de tipus pybox. La segona part de la memòria es centra en l’estudi d’enantioinducció que proporciona un nou organocatalitzador en les addicions de Michael esmentades en l’apartat anterior. Aquest catalitzador està format pel derivat de la cincona 11-(9-mercaptononiltio)-10,11-dihidrocinconina suportat en nanopartícules d’or.
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Physical damage and disease are known to lead to changes in the oxylipin signature of plants. We searched for oxylipins produced in response to both wounding and pathogenesis in Arabidopsis leaves. Linoleic acid 9- and 13-ketodienes (KODEs) were found to accumulate in wounded leaves as well as in leaves infected with the pathogen Pseudomonas syringae pv. tomato (Pst). Quantification of the compounds showed that they accumulated to higher levels during the hypersensitive response to Pst avrRpm1 than during infection with a Pst strain lacking an avirulence gene. KODEs are Michael addition acceptors, containing a chemically reactive alpha,beta-unsaturated carbonyl group. When infiltrated into leaves, KODEs were found to induce expression of the GST1 gene, but vital staining indicated that these compounds also damaged plant cells. Several molecules typical of lipid oxidation, including malonaldehyde, also contain the alpha,beta-unsaturated carbonyl reactivity feature, and, when delivered in a volatile form, powerfully induced the expression of GST1. The results draw attention to the potential physiological importance of naturally occurring Michael addition acceptors in plants. In particular, these compounds could act directly, or indirectly via cell damage, as powerful gene activators and might also contribute to host cell death.
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[Liber physiognomiae (latin). 1486]
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[Liber physiognomiae (latin). 1477]
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[Liber physiognomiae (latin). 1486]