Mary E. Wilkins Freeman.

Mode of access: Internet.

The works of the Right Honourable Lady Mary Wortley Montagu, including her correspondence, poems, and essays /

Mode of access: Internet.

Authentic and interesting memoirs of Mrs. Clarke, : from her infancy to the present time. : Likewise, a brief account of Mr. Wardle's charges, relative to His Royal Highness the Duke of York: : together with the minutes of evidence, as taken in the House of Commons. : From authentic documents. : Illustrated with a beautiful portrait of Mrs. Clarke.

"Authentic documents, &c. &c.," p. [31]-371, printed in two columns.

The triumph of virtue : the trial of Miss Mary Ann Tocker, who plead her own cause, for an alleged libel on R. Gurney, Jun. ... to which is prefixed a letter to Miss Tocker, and to which is added an address to jury-men on their duties as jurors, and especially on trials for criminal libel /

"From the third New-York edition."

The Mary Jane papers, a book for girls,

Mode of access: Internet.

The life and letters of Lady Sarah Lennox, 1745-1826, daughter of Charles, 2nd Duke of Richmond, and successively the wife of Sir Thomas Charles Bunbury, Bart., and of the Hon. George Napier; also a short political sketch of the years 1760 to 1763,

Mode of access: Internet.

Notes on the Cathedral Church of St. Mary the Blessed Virgin Salisbury (founded April 28, 1220) /

Largely written by J.M.J. Fletcher, with a chapter on "The Library, and the use of Sarum," by Christopher Wordsworth.

Data compilation on the biological response to ocean acidification: environmental and experimental context of data sets and related literature

The exponential growth of studies on the biological response to ocean acidification over the last few decades has generated a large amount of data. To facilitate data comparison, a data compilation hosted at the data publisher PANGAEA was initiated in 2008 and is updated on a regular basis (doi:10.1594/PANGAEA.149999). By January 2015, a total of 581 data sets (over 4 000 000 data points) from 539 papers had been archived. Here we present the developments of this data compilation five years since its first description by Nisumaa et al. (2010). Most of study sites from which data archived are still in the Northern Hemisphere and the number of archived data from studies from the Southern Hemisphere and polar oceans are still relatively low. Data from 60 studies that investigated the response of a mix of organisms or natural communities were all added after 2010, indicating a welcomed shift from the study of individual organisms to communities and ecosystems. The initial imbalance of considerably more data archived on calcification and primary production than on other processes has improved. There is also a clear tendency towards more data archived from multifactorial studies after 2010. For easier and more effective access to ocean acidification data, the ocean acidification community is strongly encouraged to contribute to the data archiving effort, and help develop standard vocabularies describing the variables and define best practices for archiving ocean acidification data.

Library and information science education 2.0 : guiding principles and models of best practice. Interview with Mary Anne Kennan.

In 2005, Stephen Abram, vice president of Innovation at SirsiDynix, challenged library and information science (LIS) professionals to start becoming “librarian 2.0.” In the last few years, discussion and debate about the “core competencies” needed by librarian 2.0 have appeared in the “biblioblogosphere” (blogs written by LIS professionals). However, beyond these informal blog discussions few systematic and empirically based studies have taken place. A project funded by the Australian Learning and Teaching Council fills this gap. The project identifies the key skills, knowledge, and attributes required by “librarian 2.0.” Eighty-one members of the Australian LIS profession participated in a series of focus groups. Eight themes emerged as being critical to “librarian 2.0”: technology, communication, teamwork, user focus, business savvy, evidence based practice, learning and education, and personal traits. Guided by these findings interviews with 36 LIS educators explored the current approaches used within contemporary LIS education to prepare graduates to become “librarian 2.0”. This video presents an example of ‘great practice’ in current LIS education as it strives to foster web 2.0 professionals.

Integrated genomic characterization of endometrial carcinoma

We performed an integrated genomic, transcriptomic and proteomic characterization of 373 endometrial carcinomas using array- and sequencing-based technologies. Uterine serous tumours and ∼25% of high-grade endometrioid tumours had extensive copy number alterations, few DNA methylation changes, low oestrogen receptor/progesterone receptor levels, and frequent TP53 mutations. Most endometrioid tumours had few copy number alterations or TP53 mutations, but frequent mutations in PTEN, CTNNB1, PIK3CA, ARID1A and KRAS and novel mutations in the SWI/SNF chromatin remodelling complex gene ARID5B. A subset of endometrioid tumours that we identified had a markedly increased transversion mutation frequency and newly identified hotspot mutations in POLE. Our results classified endometrial cancers into four categories: POLE ultramutated, microsatellite instability hypermutated, copy-number low, and copy-number high. Uterine serous carcinomas share genomic features with ovarian serous and basal-like breast carcinomas. We demonstrated that the genomic features of endometrial carcinomas permit a reclassification that may affect post-surgical adjuvant treatment for women with aggressive tumours.