A correct statement and review of the trial of Joseph T. Buckingham for an alledged libel on the Rev. John N. Maffit, before the Hon. Josiah Quincy, judge of the Municipal court, Dec. 16, 1822.

Mode of access: Internet.

John Bachman, the pastor of St. John's Lutheran Church, Charleston.

Life and letters, ed. by C.L. Bachman.

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression

Uromodulin (UMOD) mutations are responsible for three autosomal dominant tubulo-interstitial nephropathies including medullary cystic kidney disease type 2 (MCKD2), familial juvenile hyperuricemic nephropathy and glomerulocystic kidney disease. Symptoms include renal salt wasting, hyperuricemia, gout, hypertension and end-stage renal disease. MCKD is part of the 'nephronophthisis-MCKD complex', a group of cystic kidney diseases. Both disorders have an indistinguishable histology and renal cysts are observed in either. For most genes mutated in cystic kidney disease, their proteins are expressed in the primary cilia/basal body complex. We identified seven novel UMOD mutations and were interested if UMOD protein was expressed in the primary renal cilia of human renal biopsies and if mutant UMOD would show a different expression pattern compared with that seen in control individuals. We demonstrate that UMOD is expressed in the primary cilia of renal tubules, using immunofluorescent studies in human kidney biopsy samples. The number of UMOD-positive primary cilia in UMOD patients is significantly decreased when compared with control samples. Additional immunofluorescence studies confirm ciliary expression of UMOD in cell culture. Ciliary expression of UMOD is also confirmed by electron microscopy. UMOD localization at the mitotic spindle poles and colocalization with other ciliary proteins such as nephrocystin-1 and kinesin family member 3A is demonstrated. Our data add UMOD to the group of proteins expressed in primary cilia, where mutations of the gene lead to cystic kidney disease.

Reports of the secretary of the Treasury of the United States,

Reports for 1801-1828 were also reprinted in 2 vols. with the reports of Alexander Hamilton on public credit, on a national bank, on manufactures, and on the establishment of a mint, prefixed. Washington, Printed by D. Green, 1828-29.

The Quarterly review.

Editors: 1809-24, William Gifford.--1824-26, J.T. Coleridge.--1826-53, J.G. Lockhart.--1853-60, Whitwell Elwin.--1860-67, William Macpherson.--1867-93, William Smith.--1894, John Murray, 1894-99, R.E. Prothero.--1899- G.W. Prothero.

Scott and his circle,

Mode of access: Internet.

Review of a pamphlet on the trust deed of the Hanover Church.

The Boston Athenaeum, in its Catalogue, suggests Lyman Beecher as possible author. Richard H. Shoemaker's A checklist of American imprints for 1828 mentions Beecher and Benjamin Wisner as possible authors.

The birds of America,

Contains bibliographies.

The Scripture testimony to the Messiah : an inquiry with a view to a satisfactory determination of the doctrine taught in the Holy Scriptures concerning the person of Christ : including a careful examination of the Rev. Thomas Belsham's calm inquiry, and of other Unitarian works on the same subject /

Vol. 2 Printed for B. J. Holdsworth and sold by Hatchard & Son and others.

The duty and doctrine of baptism : in thirteen sermons /

Shaw-Shoemaker

Sermons /

Shaw-Shoemaker

Four discourses on the sacrifice and priesthood of Jesus Christ : and on atonement and redemption /

Includes index.

The story of Commander Allen Gardiner, R.N., with sketches of missionary work in South America.

Mode of access: Internet.

Memoirs of Sir Walter Scott,

On back of cover: Author's edition with Turner's plates.

Memorial addresses on the life and character of James B. Beck (a Senator from Kentucky) delivered in the Senate and House of Representatives August 23 and September 13, 1890.

Mode of access: Internet.