Maturity of Concrete: Field Implementation, MLR-96-1, 1996

The result and experience of field implementation of the maturity method on 14 portland cement concrete (PCC) paving and patching projects during 1995 are summarized in this report. The procedure for developing reference PCC maturity-strength curve of concrete is discussed. Temperature measurement as well as effects of datum temperature, entrained air content and type of aggregate on maturity-strength relationship are examined. Some limitations of the maturity method are discussed. The available field experience and results indicate that the maturity method provides a simple approach to determine strength of concrete, and can be easily implemented in field paving and patching projects. The use of the maturity method may result in reduced project construction time.

Laboratory Study of the Leachate from Crushed Portland Cement Concrete Base Material, MLR-96-04, 1999

Since the 1980s, the Iowa Department of Transportation has increased its use of recycled Portland Cement Concrete (PCC) as drainable base material below some new pavements. Water flowing out of the longitudinal drains on projects having recycled PCC drainable bases was found to have a high pH value. The high pH water impedes vegetation growth and becomes a contributing factor to soil erosion at the drain outlet. In addition, the high pH water contributes to the growth of crystalline deposits on the drain outlet wire mesh rodent guard and in some cases caused it to become completely blocked. This research determined which of three choices of recycled PCC drainable base material, gradation, and design would give the lowest pH value in the drain discharge water. The drainable base material having its fines separated out and placed as a 2-in. (5.1-mm) bottom layer, below the remaining coarse material, generally gave pH values around 11.2 while other designs tested gave pH values around 11.5.

Estudio de la calidad del aceite de oliva virgen de la Denominación de Origen «Les Garrigues» (Lleida) durante la campaña 1995/96

Departamento de Tecnología de Alimentos, Escuela Técnica Superior de Ingeniería Agraria, Universidad de Lleida. Centro UdL-IRTA. Avda. Alcalde Revira Roure, 177. 25198 Lleida, España. RESUMEN Estudio de la calidad del aceite de oliva virgen de la Denominación de Origen «Les Garrigues» (Lleida) durante la campaña 1995/96. La Denominación de Origen «Les Garrigues» se sitúa en el extremo meridional de la provincia de Lleida. La gran mayoría del aceite producido en esta D.O. corresponde a la categoría de virgen extra y posee unas características organolépticas muy peculiares, derivadas del fruto de origen, la variedad «Arbequina» y de su cuidada elaboración. La aplicación en la zona de modemas técnicas de cultivo del olivo y las nuevas tecnologías de extracción del aceite, hacen necesario un estudio de su composición en campañas sucesivas, con el fin de determinar si la calidad se pudiera ver afectada. El presente trabajo se centra en la caracterización de los aceites producidos en la D.O. «Les Garrigues» durante la campaña 1995/96. Los aceites obtenidos presentan un grado de acidez medio de 0.17%, índice de peróxidos de 6.9 meq/kg de aceite y un K270 de 0.21, valores todos ellos dentro de los criterios de calidad que establece la Reglamentación de la D.O. El contenido medio de polifenoles totales en el aceite es de 152 ppm, observándose una gran variabilidad entre las almazaras muestreadas. La concentración de clorofilas va de 15 mg/kg de aceite, al inicio de campaña, a 6 mg/kg al final de la misma. La concentración de carotenoides se reduce paralelamente, pasando de 12.6 a 4.6 mg/kg de aceite, al final de campaña. El color, en base a la escala visual ABT y a las coordenadas CIELAB, se mantiene dentro de los tonos del amarillo y no presenta diferencias importantes entre aceites de principio y final de campaña.

Once-daily dolutegravir versus darunavir plus ritonavir for treatment-naive adults with HIV-1 infection (FLAMINGO): 96 week results from a randomised, open-label, phase 3b study.

BACKGROUND: The primary analysis of the FLAMINGO study at 48 weeks showed that patients taking dolutegravir once daily had a significantly higher virological response rate than did those taking ritonavir-boosted darunavir once daily, with similar tolerability. We present secondary efficacy and safety results analysed at 96 weeks. METHODS: FLAMINGO was a multicentre, open-label, phase 3b, non-inferiority study of HIV-1-infected treatment-naive adults. Patients were randomly assigned (1:1) to dolutegravir 50 mg or darunavir 800 mg plus ritonavir 100 mg, with investigator-selected combination tenofovir and emtricitabine or combination abacavir and lamivudine background treatment. The main endpoints were plasma HIV-1 RNA less than 50 copies per mL and safety. The non-inferiority margin was -12%. If the lower end of the 95% CI was greater than 0%, then we concluded that dolutegravir was superior to ritonavir-boosted darunavir. This trial is registered with ClinicalTrials.gov, number NCT01449929. FINDINGS: Of 595 patients screened, 488 were randomly assigned and 484 included in the analysis (242 assigned to receive dolutegravir and 242 assigned to receive ritonavir-boosted darunavir). At 96 weeks, 194 (80%) of 242 patients in the dolutegravir group and 164 (68%) of 242 in the ritonavir-boosted darunavir group had HIV-1 RNA less than 50 copies per mL (adjusted difference 12·4, 95% CI 4·7-20·2; p=0·002), with the greatest difference in patients with high viral load at baseline (50/61 [82%] vs 32/61 [52%], homogeneity test p=0·014). Six participants (three since 48 weeks) in the dolutegravir group and 13 (four) in the darunavir plus ritonavir group discontinued because of adverse events. The most common drug-related adverse events were diarrhoea (23/242 [10%] in the dolutegravir group vs 57/242 [24%] in the darunavir plus ritonavir group), nausea (31/242 [13%] vs 34/242 [14%]), and headache (17/242 [7%] vs 12/242 [5%]). INTERPRETATION: Once-daily dolutegravir is associated with a higher virological response rate than is once-daily ritonavir-boosted darunavir. Dolutegravir compares favourably in efficacy and safety to a boosted darunavir regimen with nucleoside reverse transcriptase inhibitor background treatment for HIV-1-infected treatment-naive patients. FUNDING: ViiV Healthcare and Shionogi & Co.

Psalmi 96

Soitinnus: lauluäänet (sopraano, tenori), poikakuoro, kamariorkesteri.

Kadettien käsityksiä ja odotuksia tulevasta kouluttajan tehtävästä – Kyselytutkimus 96. kadettikurssin maasotalinjan kadeteille kesällä 2011

Tutkimuksen tarkoitus oli selvittää millaisin odotuksin kadetit siirtyvät työelämään, mikä heidän mielestä hyvä kouluttajuus on, sekä millaisia kehittämistarpeita he näkevät Kadettikoulun tämän päivän kouluttajakoulutuksessa. Tutkimuksessa käytettiin laadullisia menetelmiä. Tutkimus suoritettiin sähköpostikyselytutkimuksena kesällä 2011, 96 kadettikurssin kadettien opiskellessa toista vuottaan Kadettikoulussa. Tutkimukseen osallistui 25 kadettia (32 %) maasotalinjasta. Tutkimus osoitti, että kadetit haluavat haastavia, monipuolisia ja mielenkiintoisia tehtäviä missä he voivat kehittää itseään kouluttajina ja sotilaina. Hyvässä kouluttajassa kadetit arvostivat eniten vanhoja tuttuja ominaisuuksia, kuten esimerkillisyyttä ja ammattitaitoa. Kadettikoulun kouluttajakoulutus sai sekä risuja että ruusuja. Suurimpana kehittämistarpeena nähtiin liian vähäinen käytännön harjoittelu. Tutkimuksen perusteella voidaan tehdä johtopäätös, että kadeteilla on oikea asenne työelämään ja kaikki mahdollisuudet kehittyä hyviksi kouluttajiksi.

Consentimento Informado Normatizado pela Resolução 196/96: Conhecimento e Opinião de Pesquisadores Brasileiros

Introdução : a Resolução 196/96, do Conselho Nacional de Saúde (Ministério da Saúde), apresenta as diretrizes regulamentadoras mais abrangentes acerca de pesquisas envolvendo seres humanos no Brasil, incluindo o conteúdo do termo de consentimento. Objetivo: apresentar o conhecimento e opinião de pesquisadores brasileiros sobre o conteúdo da Resolução 196/96 do Conselho Nacional de Saúde em relação ao consentimento informado. Sujeitos e Métodos: 46 responsáveis pela área de ginecologia em universidades, 4 diretores de centros de pesquisa e 31 pesquisadores, que participaram de um estudo sobre regulação da fecundidade nos 12 meses anteriores a setembro de 2000, completaram um questionário auto-respondido. Para a análise dos dados foi utilizado o teste de chi². Resultados: a maioria dos participantes: declarou conhecer a Resolução e que a considerava adequada, embora difícil de ser cumprida; opinou que todas as pesquisas deviam ter um termo de consentimento; sabia que o termo deve assegurar o sigilo. Significativamente mais pesquisadores do que responsáveis/diretores sabiam que o termo tinha que ser elaborado pelo pesquisador principal, em duas vias. Mais responsáveis/diretores do que pesquisadores disseram que os participantes sempre devem assinar ou colocar a impressão digital no termo e consideraram que a forma de ressarcimento das despesas decorrentes de participar no estudo deve sempre constar no documento. Conclusões: apesar da difusão dada à Resolução 196/96, nem todos os sujeitos deste estudo a conheciam, mesmo estando ligados a uma universidade ou centro de pesquisa. A maioria foi favorável aos conteúdos exigidos pela Resolução para o consentimento informado.

Lisäluettelo ohjekirjeen N:o 96 liitteessä olevaan leipäkorttien jaossa noudatettavaan ammattiryhmittelyyn

17 x 26 cm

Tilläggsförteckning till den i instruktionsbrev N:o 96 förefintliga yrkesförteckningen, viken bör iakttagas vid distributionen av brödkort

17 x 26 cm

Les sept merveilles du n° 7 : parodie électro-physico-magnético-burlesco-féerico-dramatico-comique en 9 tableaux dont un prologue et un entr'acte. [suivi de ] L'ami François : comédie-vaudeville en 1 acte. Livr. 96 / par MM. Cormon et Eugène Grangé ; par MM. Bourdois et Émile Colliot

Collection : Théâtre contemporain illustré ; 96e et 97e livraisons

Les sept merveilles du n° 7 : parodie électro-physico-magnético-burlesco-féerico-dramatico-comique en 9 tableaux dont un prologue et un entr'acte. [suivi de ] L'ami François : comédie-vaudeville en 1 acte. Livr. 96 / par MM. Cormon et Eugène Grangé ; par MM. Bourdois et Émile Colliot

Collection : Théâtre contemporain illustré ; 96e et 97e livraisons