M. Tullius Cicero inde ab Idibus Martiis 710 usque ad Calendas Januarias 711 p. R. c. [microform]...

Academic program.

Organizational, direct support, and general support maintenance repairs parts and special tools list (including depot maintenance repair parts and special tools) : disperser, riot control agent, portable, M3, FSN 1040-711-8296.

"27 April 1972."

Operator and organizational maintenance manual : disperser, riot control agent, portable, M3 (FSN 1040-711-8296).

"February 1972."

Direct support and general support maintenance manual : disperser, riot control agent, portable, M3, FSN 1040-711-8296.

"February 1972."

Direct support and general support maintenance manual including repair parts and special tools lists (including depot maintenance repair parts and special tools) : rifle, 7.62-MM, M14, W/E (1005-589-1271); rifle, 7.62-MM, M14A1, W/E (1005-072-5011); bipod, rifle, M2 (1005-711-6202).

Includes index.

Political status of Puerto Rico : hearings before the Committee on Energy and Natural Resources, United States Senate, One Hundred First Congress, first session, on S. 710, S. 711, and S. 712.

"San Juan, Puerto Rico, June 16, 17, and 19, 1989"--Pt. 2.

Six new cases confirm the clinical molecular profile of complete combined 17α-hydroxylase/ 17,20-lyase deficiency in Brazil

In 2004, Costa-Santos and cols. reported 24 patients from 19 Brazilian families with 17α-hydroxylase deficiency and showed that p.W406R and p.R362C corresponded to 50% and 32% of CYP17A1 mutant alleles, respectively. The present report describes clinical and molecular data of six patients from three inbred Brazilian families with 17α-hydroxlyse deficiency. All patients had hypogonadism, amenorrhea and hypertension at diagnosis. Two sisters were found to be 46,XY with both gonads palpable in the inguinal region. All patients presented hypergonadotrophic hypogonadism, with high levels of ACTH (> 104 ng/mL), suppressed plasmatic renin activity, low levels of potassium (< 2.8 mEq/L) and elevated progesterone levels (> 4.4 ng/mL). Three of them, including two sisters, were homozygous for p.W406R mutation and the other three (two sisters and one cousin) were homozygous for p.R362C. The finding of p.W406R and p.R362C in the CYP17A1 gene here reported in additional families, confirms them as the most frequent mutations causing complete combined 17α-hydroxylase/17,20-lyase deficiency in Brazilian patients.

Antibacterial modified diketopiperazines from two ascidians of the genus Didemnum

The chemical investigation of the crude extract of an ascidian of the genus Didemnumled to the isolation of the modified diketopiperazine rodriguesines A (1) and (2) as a mixture of homologues, which could be identified by analysis of spectroscopic data including MS/MS experiments. The investigation of a second Didemnumsp. led to the isolation of N-acetyl-rodriguesine A (3) and N-acetyl-rodriguesine B (4). The absolute configuration of compounds 1and 2could be established by hydrolysis and Marfey's analysis and comparison with literature data reported for compound 3, previously obtained as a synthetic product. The mixture of 1and 2displayed moderate antibiotic activity against a clinical isolate of Streptococcus mutansand against S. mutansUA159 and Staphylococcus aureusATCC6538.